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Shu-Feng Zhou, Bo Wang, Li-Ping Yang & Jun-Ping Liu. (2010) Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2. Drug Metabolism Reviews 42:2, pages 268-354.
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Leonard Kamen, Herbert R. Henney$suffix/text()$suffix/text() & Jacob D. Runyan. (2008) A practical overview of tizanidine use for spasticity secondary to multiple sclerosis, stroke, and spinal cord injury. Current Medical Research and Opinion 24:2, pages 425-439.
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Articles from other publishers (21)
Vamshi Krishna Jogiraju, Tycho Heimbach, Yuliana Toderika & David R. Taft. (2021) Physiologically based pharmacokinetic modeling of altered tizanidine systemic exposure by CYP1A2 modulation: Impact of drug-drug interactions and cigarette consumption. Drug Metabolism and Pharmacokinetics 37, pages 100375.
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Jingchao Guo, Xiaohui Zhu, Sara Badawy, Awais Ihsan, Zhenli Liu, Changqing Xie & Xu Wang. (2021) Metabolism and Mechanism of Human Cytochrome P450 Enzyme 1A2. Current Drug Metabolism 22:1, pages 40-49.
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Dino Luethi, Marius C. Hoener, Stephan Krähenbühl, Matthias E. Liechti & Urs Duthaler. (2019) Cytochrome P450 enzymes contribute to the metabolism of LSD to nor-LSD and 2-oxo-3-hydroxy-LSD: Implications for clinical LSD use. Biochemical Pharmacology 164, pages 129-138.
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Gary W. Jay & Robert L. Barkin. (2017) Primary Headache Disorders- Part 2: Tension-type headache and medication overuse headache. Disease-a-Month 63:12, pages 342-367.
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C. W. Locuson, P. Williams, J. M. Adcock & J. S. Daniels. (2016) Evaluation of tizanidine as a marker of canine CYP1A2 activity. Journal of Veterinary Pharmacology and Therapeutics 39:2, pages 122-130.
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Ya-Wen Hsiao, Carl Petersson, Mats A. Svensson & Ulf Norinder. (2012) A Pragmatic Approach Using First-Principle Methods to Address Site of Metabolism with Implications for Reactive Metabolite Formation. Journal of Chemical Information and Modeling 52:3, pages 686-695.
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Peter John, Islam Ullah Khan, Mehmet Akkurt, Muhammad Shahid Ramzan & Shahzad Sharif. (2011)
5-Chloro-
N
-(4,5-dihydro-1
H
-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine (tizanidine)
. Acta Crystallographica Section E Structure Reports Online 67:4, pages o838-o839.
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H. R. HenneyIIIIII & J. D. Runyan. (2008) A clinically relevant review of tizanidine hydrochloride dose relationships to pharmacokinetics, drug safety and effectiveness in healthy subjects and patients. International Journal of Clinical Practice 62:2, pages 314-324.
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Janne T. Backman, Marika T. Schröder & Pertti J. Neuvonen. (2007) Effects of gender and moderate smoking on the pharmacokinetics and effects of the CYP1A2 substrate tizanidine. European Journal of Clinical Pharmacology 64:1, pages 17-24.
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Janne T. Backman, Marjo J. Karjalainen, Mikko Neuvonen, Jouko Laitila & Pertti J. Neuvonen. (2006) Rofecoxib is a potent inhibitor of cytochrome P450 1A2: studies with tizanidine and caffeine in healthy subjects. British Journal of Clinical Pharmacology 62:3, pages 345-357.
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Jaymin Shah, Keith A. Wesnes, Rosemary A. Kovelesky & Herbert R. HenneyIIIIII. (2006) Effects of food on the single-dose pharmacokinetics/pharmacodynamics of tizanidine capsules and tablets in healthy volunteers. Clinical Therapeutics 28:9, pages 1308-1317.
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Janne T. Backman, Marika T. Granfors & Pertti J. Neuvonen. (2006) Rifampicin is only a weak inducer of CYP1A2-mediated presystemic and systemic metabolism: studies with tizanidine and caffeine. European Journal of Clinical Pharmacology 62:6, pages 451-461.
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Neeraj Kaul, S.R. Dhaneshwar, Himani Agrawal, Abhijit Kakad & Bharat Patil. (2005) Application of HPLC and HPTLC for the simultaneous determination of tizanidine and rofecoxib in pharmaceutical dosage form. Journal of Pharmaceutical and Biomedical Analysis 37:1, pages 27-38.
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Marika T. Granfors, Janne T. Backman, Jouko Laitila & Pertti J. Neuvonen. (2004) Tizanidine is mainly metabolized by cytochrome P450 1A2 in vitro. British Journal of Clinical Pharmacology 57:3, pages 349-353.
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Kazuyuki Imanaga, Zen'ichiro Wajima, Tetsuo Inoue & Ryo Ogawa. (2004) Effect of Oral Tizanidine on Local-anesthetic Infiltration Pain during Epidural Catheterization. Journal of Nippon Medical School 71:2, pages 105-110.
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K.R Mahadik, A.R Paradkar, Himani Agrawal & Neeraj Kaul. (2003) Stability-indicating HPTLC determination of tizanidine hydrochloride in bulk drug and pharmaceutical formulations. Journal of Pharmaceutical and Biomedical Analysis 33:4, pages 545-552.
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Zen’ichiro Wajima, Tatsusuke Yoshikawa, Akira Ogura, Kazuyuki Imanaga, Toshiya Shiga, Tetsuo Inoue & Ryo Ogawa. (2002) Oral Tizanidine, an α2-Adrenoceptor Agonist, Reduces the Minimum Alveolar Concentration of Sevoflurane in Human Adults. Anesthesia & Analgesia 95:2, pages 393-396.
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Zen’ichiro Wajima, Tatsusuke Yoshikawa, Akira Ogura, Kazuyuki Imanaga, Toshiya Shiga, Tetsuo Inoue & Ryo Ogawa. (2002) Oral Tizanidine, an α2-Adrenoceptor Agonist, Reduces the Minimum Alveolar Concentration of Sevoflurane in Human Adults. Anesthesia & Analgesia 95:2, pages 393-396.
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Howard S. Smith & Amy E. Barton. (2016) Tizanidine in the management of spasticity and musculoskeletal complaints in the palliative care population. American Journal of Hospice and Palliative Medicine® 17:1, pages 50-58.
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Margitta Albinus, Gudrun Amschler, Uwe Amschler, Erwin von Angerer, Wolfgang Barthel, Andrea Bauer, Kurt Bauer, Jürgen Beckmann, Winfried Beil, Jürgen Beitz, Petra Berscht, Thorsten Beyrich, Katja Binder, Roswitha Böhme, Hans-Hubertus Borchert, Franz Bracher, Helmut Bräunlich, Kerstin Brinkmann, Franz von Bruchhausen, Kay Brune, Axel Büge, Wolfram Christ, Monika Cimbollek, Rolf Daniels, Gerd Dannhardt, Hans-Jürgen Duchstein, Siegfried Ebel, Kurt Eger, Peter Emig, Thomas Erker, Maria S. Fernandez-Alfonso, August Wilhelm Frahm, Margarete Frahm, Klaus-Jürgen Freundt, Detlef Geffken, Ulrich Geis, Erika Glusa, Berthold Göber, Jochen Gödicke, Margarete Goppelt-Strübe, Wilhelm Gössling, Annette Graul, Sibylle Greiner, Adolf Grisk, Michael Grosam, Markus von Gruchalla, Michael Gütschow, Axel Haberkorn, Eberhard Hackenthal, Annette Häfner, Boris Haluszczynski, Achim Harder, Sabine Hartmann, Susanne Hartmann, Dieter Heber, Gerhard Heinemeyer, Andreas Hensel, Sibylle Hoedt-Schmidt, Hermann Hoffmann, Ute Hoffmann-Schollmayer, Ulrike Holzgrabe, Martin Hug, Wolfgang Ibrom, Elisabeth Inkmann, Jens Jürgens, Brigitte Kaiser, Dieter-Abbo Kalbhen, Nasser Khudeir, Werner Kiefer, Doris Kleinsorge, Christoph Klett, Stephanie Klett, Martin Klingmüller, H.-P. Klöcking, Gerd Kobal, Axel Kramer, Mareta Kreher, Gottfried Kreutz, Reinhard Kroker, Dorothea Landsiedel-Maier, Jochen Lehmann, Marion Sylvia Lehner, Stefan Leiner, Hans Löwe, Johannes Mann, Detlef Manns, Wolfgang Matthiessen, Andreas Maurer, Wolfgang Meindl, Klaus Menges, Paul Messinger, Hans-Jürgen Mest, Frank Peter Meyer, J. Mollière, Rudolf Morgenstern, Wolfgang Morick, Joachim Mössner, Christa Müller, Daniel Müller, Klaus Müller, Walter Müller, Alexander Mülsch, Tilo Netzer, Michael Neugebauer, Ulf Niemeyer, Peter Nuhn, Bernd Nürnberg, Joachim Oertel, Michael Oettel, Hartmut Oßwald, Robert Ott, Tilmann Ott, Thomas Otzen, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Martina Pickert, Andreas Pies, Klaus Pietrzik, Detlef Preiss, Helmut Priewer, Olaf Queckenberg, Eberhard Reimann, Jörg Remien, Rainer Rettig, Andreas Reymann, Joachim Richter, Hans Rommelspacher, Ulrich Rose, Gerhard Rücker, Klaus Schaefer, Helmut Schlager, Werner Schleicher, Hildegard Schleinitz, Wolfgang Schlichter, Helmut Schmidhammer, Gerhard Schmidt, Timo Schmidt, Johannes Schräder, Thomas Schulz, Gert Schulze, Peter Schwanz, Helmut Schwilden, Monika Serke, Gisela Skopp, Marcus Spohn, Ralf Stahlmann, Johannes-Peter Stasch, Christian Steffen, Jürgen Steinmeyer, Karl-Heinz Surborg, Ulf Sürig, Istvan Szelenyi, Reinhard Troschütz, Michael Verborg, Eugen J. Verspohl, Franz-Josef Volk, Heinz Walther, Horst Weber, Judith Wede, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Hilke Winterhoff, Reinhold Wintersteiger, Frauke Woltmann, Diaa Youssef & A. Ziegler. 1994. Hagers Handbuch der Pharmazeutischen Praxis. Hagers Handbuch der Pharmazeutischen Praxis
765
1129
.
Jean-Michel Kauffmann, Beatriz Lopez Ruiz, Mercedes Ferrandis Gotori & Gaston J. Patriarche. (1992) Electrochemical behaviour of tizanidine at solid electrodes. Journal of Pharmaceutical and Biomedical Analysis 10:10-12, pages 763-767.
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