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Xenobiotica
the fate of foreign compounds in biological systems
Volume 19, 1989 - Issue 11
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Research Article

Propofol: Assay and regional mass balance in the sheep

L. E. Mather Department of Anaesthesia and Intensive Care, Flinders Medical Centre, The Flinders University of South Australia, Adelaide, SA, 5042, Australia
,
D. G. Selby Department of Anaesthesia and Intensive Care, Flinders Medical Centre, The Flinders University of South Australia, Adelaide, SA, 5042, Australia
,
W. B. Runciman Department of Anaesthesia and Intensive Care, Flinders Medical Centre, The Flinders University of South Australia, Adelaide, SA, 5042, Australia
&
C. F. McLean Department of Anaesthesia and Intensive Care, Flinders Medical Centre, The Flinders University of South Australia, Adelaide, SA, 5042, Australia
Pages 1337-1347 | Received 25 Aug 1988, Accepted 13 Feb 1989, Published online: 22 Sep 2008

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M. Grossherr, A. Hengstenberg, L. Dibbelt, B.-W. Igl, R. Noel, A. v. d. Knesebeck, P. Schmucker & H. Gehring. (2009) Blood gas partition coefficient and pulmonary extraction ratio for propofol in goats and pigs. Xenobiotica 39:10, pages 782-787.
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P. A. Gray, G. R. Park, I. D. Cockshott, E. J. Douglas, B. Shuker & P. J. Simons. (1992) Propofol metabolism in man during the anhepatic and reperfusion phases of liver transplantation. Xenobiotica 22:1, pages 105-114.
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P. J. Simons, I. D. Cockshott, E. J. Douglas, E. A. Gordon, S. Knott & R. J. Ruane. (1991) Distribution in female rats of an anaesthetic intravenous dose of 14C-propofol. Xenobiotica 21:10, pages 1325-1335.
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Articles from other publishers (30)

Amanda M. Kleiman & Keith E. Littlewood. 2019. Principles and Practice of Anesthesia for Thoracic Surgery. Principles and Practice of Anesthesia for Thoracic Surgery 131 149 .
Minako Ishii-Maruhama, Hitoshi Higuchi, Mai Nakanou, Yuka Honda-Wakasugi, Akiko Yabuki-Kawase, Shigeru Maeda & Takuya Miyawaki. (2018) In vitro changes in the proportion of protein-unbound-free propofol induced by valproate. Journal of Anesthesia 32:5, pages 688-693.
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Mauricio Deschk, Juliana T Wagatsuma, Marcelo A Araújo, Guilherme GF Santos, Sergio SR Júnior, Caio JX Abimussi, Carlos E Siqueira, Jéssica CL Motta, Silvia HV Perri & Paulo SP Santos. (2016) Continuous infusion of propofol in calves: bispectral index and hemodynamic effects. Veterinary Anaesthesia and Analgesia 43:3, pages 309-315.
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Luciane Tourem Gressler, Fernando Jonas Sutili, Sílvio Teixeira da Costa, Thaylise Vey Parodi, Tanise da Silva Pês, Gessi Koakoski, Leonardo José Gil Barcellos & Bernardo Baldisserotto. (2014) Hematological, morphological, biochemical and hydromineral responses in Rhamdia quelen sedated with propofol. Fish Physiology and Biochemistry 41:2, pages 463-472.
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Lauren Yeazell & Keith Littlewood. 2011. Principles and Practice of Anesthesia for Thoracic Surgery. Principles and Practice of Anesthesia for Thoracic Surgery 103 119 .
M. Grossherr, A. Hengstenberg, T. Meier, L. Dibbelt, B.W. Igl, A. Ziegler, P. Schmucker & H. Gehring. (2009) Propofol concentration in exhaled air and arterial plasma in mechanically ventilated patients undergoing cardiac surgery. British Journal of Anaesthesia 102:5, pages 608-613.
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Carolyn M McKune, Robert J Brosnan, Michael J Dark & Gary J Haldorson. (2008) Safety and efficacy of intramuscular propofol administration in rats. Veterinary Anaesthesia and Analgesia 35:6, pages 495-500.
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K. Takata, T. Kurita, Y. Morishima, K. Morita, M. Uraoka & S. Sato. (2008) Do the kidneys contribute to propofol elimination?. British Journal of Anaesthesia 101:5, pages 648-652.
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Lysa P. Posner, Makoto Asakawa & Hollis N. Erb. (2008) Use of propofol for anesthesia in cats with primary hepatic lipidosis: 44 cases (1995–2004). Journal of the American Veterinary Medical Association 232:12, pages 1841-1843.
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Logan J. Voss, Guy Ludbrook, Cliff Grant, Richard Upton & James W. Sleigh. (2007) A Comparison of Pharmacokinetic/Pharmacodynamic versus Mass-Balance Measurement of Brain Concentrations of Intravenous Anesthetics in Sheep. Anesthesia & Analgesia 104:6, pages 1440-1446.
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D. Takizawa, E. Sato, H. Hiraoka, A. Tomioka, K. Yamamoto, R. Horiuchi & F. Goto. (2005) Changes in apparent systemic clearance of propofol during transplantation of living related donor liver. British Journal of Anaesthesia 95:5, pages 643-647.
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Stephen A Greene. (2003) Protocols for anesthesia of cattle. Veterinary Clinics of North America: Food Animal Practice 19:3, pages 679-693.
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Da Zheng, Richard N. Upton & Allison M. Martinez. (2003) The Contribution of the Coronary Concentrations of Propofol to Its Cardiovascular Effects in Anesthetized Sheep. Anesthesia & Analgesia, pages 1589-1597.
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T. Tsubokawa, K. Yamamoto, A. Komuro, S. Ishizuka & T. Kobayashi. (2003) Propofol pharmacokinetics in a dwarfism patient. Acta Anaesthesiologica Scandinavica 47:4, pages 488-490.
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B.M.Q. Weaver, G.E. Staddon & W.W. Mapleson. (2001) Tissue/blood and tissue/water partition coefficients for propofol in sheep † ‡. British Journal of Anaesthesia 86:5, pages 693-703.
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R. N. UptonG. L. Ludbrook & C. Grant. (2019) The Cerebral and Systemic Kinetics of Thiopentone and Propofol in Halothane Anaesthetized Sheep. Anaesthesia and Intensive Care 29:2, pages 117-123.
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Takumi Taniguchi, Ken Yamamoto, Nobuko Ohmoto, Keisuke Ohta & Tsutomu Kobayashi. (2000) Effects of propofol on hemodynamic and inflammatory responses to endotoxemia in rats. Critical Care Medicine 28:4, pages 1101-1106.
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Ken Yamamoto, Tsunehisa Tsubokawa, Toshihiro Yagi, Shuichi Ishizuka, Shigeo Ohmura & Tsutomu Kobayashi. (1999) The influence of hypoxia and hyperoxia on the kinetics of propofol emulsion. Canadian Journal of Anesthesia/Journal canadien d'anesthésie 46:12, pages 1150-1155.
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Rn Upton & Dj Doolette. (1999) KINETIC ASPECTS OF DRUG DISPOSITION IN THE LUNGS. Clinical and Experimental Pharmacology and Physiology 26:5-6, pages 381-391.
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Paul A. Dickinson & Glyn Taylor. (1998) Route dependent pulmonary first-pass metabolism of a series of biphenylacetic acid esters in rats. European Journal of Pharmaceutical Sciences 6:1, pages 11-18.
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HUI‐CHU LIN, RAM C. PUROHIT & TOM A. POWE. (2008) Anesthesia in Sheep With Propofol or With Xylazine‐Ketamine Followed by Halothane. Veterinary Surgery 26:3, pages 247-252.
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William J. Tranquilli & Kurt A. Grimm. (1996) Pharmacology of Drugs used for Anesthesia and Sedation. Veterinary Clinics of North America: Food Animal Practice 12:3, pages 501-529.
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G. L. Ludbrook, R. N. Upton, C. Grant & E. C. Gray. (2019) Brain and Blood Concentrations of Propofol after Rapid Intravenous Injection in Sheep, and Their Relationships to Cerebral Effects. Anaesthesia and Intensive Care 24:4, pages 445-452.
Crossref
Robert H. Dowrie, William F. Ebling, Jaap W. Mandema & Donald R. Stanski. (1996) High-performance liquid chromatographic assay of propofol in human and rat plasma and fourteen rat tissues using electrochemical detection. Journal of Chromatography B: Biomedical Sciences and Applications 678:2, pages 279-288.
Crossref
Shou-Zen Fan, Hsiu-Ying Yu, Yung-Liang Chen & Chien-Chiang Liu. (1995) Propofol Concentration Monitoring in Plasma or Whole Blood by Gas Chromatography and High-Performance Liquid Chromatography. Anesthesia & Analgesia 81:1, pages 175-178.
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Shou-Zen Fan, Hsiu-Ying Yu, Yung-Liang Chen & Chien-Chiang Liu. (1995) Propofol Concentration Monitoring in Plasma or Whole Blood by Gas Chromatography and High-Performance Liquid Chromatography. Anesthesia & Analgesia 81:1, pages 175-178.
Crossref
Carol A. Moote. (1994) ANESTHESIA FOR RENAL TRANSPLANTATION. Anesthesiology Clinics of North America 12:4, pages 691-715.
Crossref
P.L. Stetson, E.F. Domino & J.R. Sneyd. (1993) Determination of plasma propofol levels using gas chromatography—mass spectrometry with selected-ion monitoring. Journal of Chromatography B: Biomedical Sciences and Applications 620:2, pages 260-267.
Crossref
I.G. Handel, B.M.Q. Weaver, G.E. Staddon & J.I. Cruz Madorran. (1991) OBSERVATIONS ON THE PHARMACOKINETICS OF PROPOFOL IN SHEEP. Journal of Veterinary Anaesthesia 18, pages 143-154.
Crossref
J.W. Sear. (1991) RECENT ADVANCES IN INTRAVENOUS ANAESTHESIA. Journal of Veterinary Anaesthesia 18, pages 9-15.
Crossref

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