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Xenobiotica
the fate of foreign compounds in biological systems
Volume 20, 1990 - Issue 11
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Original Article

Autoinduction of rifabutin metabolism in man

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Pages 1113-1119 | Received 20 Sep 1989, Accepted 01 Apr 1990, Published online: 27 Aug 2009

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Read on this site (8)

Susan S. Schiffman & Kristina I. Rother. (2013) Sucralose, A Synthetic Organochlorine Sweetener: Overview Of Biological Issues. Journal of Toxicology and Environmental Health, Part B 16:7, pages 399-451.
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Margherita Strolin Benedetti, Rhys Whomsley, Italo Poggesi, Willi Cawello, François-Xavier Mathy, Marie-Laure Delporte, Peggy Papeleu & Jean-Baptiste Watelet. (2009) Drug metabolism and pharmacokinetics. Drug Metabolism Reviews 41:3, pages 344-390.
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G. Krishna, A. Parsons, B. Kantesaria & T. Mant. (2007) Evaluation of the pharmacokinetics of posaconazole and rifabutin following co-administration to healthy men. Current Medical Research and Opinion 23:3, pages 545-552.
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M. STROLIN BENEDETTI & M. BANI. (1999) METABOLISM-BASED DRUG INTERACTIONS INVOLVING ORAL AZOLE ANTIFUNGALS IN HUMANS*. Drug Metabolism Reviews 31:3, pages 665-717.
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J.N. Zhang, X.G. Liu, M. Zhu, F.C.K. Chiu & R.C. Li. (1998) Assessment of Presystemic Factors on the Oral Bioavailability of Rifampicin Following Multiple Dosing. Journal of Chemotherapy 10:5, pages 354-359.
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T. MAE, K. HOSOE, T. YAMAMOTO, T. HIDAKA, T. OHASHI, J. M. KLEEMAN & P. E. ADAMS. (1998) Effect of a new rifamycin derivative, rifalazil, on liver microsomal enzyme induction in rat and dog. Xenobiotica 28:8, pages 759-766.
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Nadja Heurlin & Björn Petrini. (1993) Treatment of Non-tuberculous Mycobacterial Infections in Patients without AIDS. Scandinavian Journal of Infectious Diseases 25:5, pages 619-623.
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Articles from other publishers (25)

Colin W. Howden, Shailja Shah, Salil N. Pendse, Elliot Offman, June S. Almenoff & Kely L. Sheldon. (2023) Physiologically‐based pharmacokinetic modelling to predict intragastric rifabutin concentrations in the treatment of Helicobacter pylori infection . Alimentary Pharmacology & Therapeutics 58:2, pages 159-167.
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Matthew C Phillips, Noah Wald-Dickler, Katherine Loomis, Brian M Luna & Brad Spellberg. (2020) Pharmacology, Dosing, and Side Effects of Rifabutin as a Possible Therapy for Antibiotic-Resistant Acinetobacter Infections. Open Forum Infectious Diseases 7:11.
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Congrong Niu, Yujin Wang, Xiaofeng Zhao, Sam Tep, Eisuke Murakami, Raju Subramanian, Bill Smith & Yurong Lai. (2019) Organic Anion-Transporting Polypeptide Genes Are Not Induced by the Pregnane X Receptor Activator Rifampin: Studies in Hepatocytes In Vitro and in Monkeys In Vivo. Drug Metabolism and Disposition 47:12, pages 1433-1442.
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Junko Tanuma, Kazumi Sano, Katsuji Teruya, Koji Watanabe, Takahiro Aoki, Haruhito Honda, Hirohisa Yazaki, Kunihisa Tsukada, Hiroyuki Gatanaga, Yoshimi Kikuchi & Shinichi Oka. (2013) Pharmacokinetics of Rifabutin in Japanese HIV-Infected Patients with or without Antiretroviral Therapy. PLoS ONE 8:8, pages e70611.
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Jiezhong Chen & Kenneth Raymond. (2006) Roles of rifampicin in drug-drug interactions: underlying molecular mechanisms involving the nuclear pregnane X receptor. Annals of Clinical Microbiology and Antimicrobials 5:1.
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Vincent Launay-Vacher, Hassane Izzedine & Gilbert Deray. (2005) Pharmacokinetic Considerations in the Treatment of Tuberculosis in Patients with Renal Failure. Clinical Pharmacokinetics 44:3, pages 221-235.
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William J. Burman, Keith Gallicano & Charles Peloquin. (2001) Comparative Pharmacokinetics and Pharmacodynamics of the Rifamycin Antibacterials. Clinical Pharmacokinetics 40:5, pages 327-341.
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M. BREDA, M.STROLIN BENEDETTI, M. BANI, C. PELLIZZONI, I. POGGESI, G. BRIANCESCHI, M. ROCCHETTI, L. DOLFI, D. SASSELLA & R. RIMOLDI. (1999) EFFECT OF RIFABUTIN ON ETHAMBUTOL PHARMACOKINETICS IN HEALTHY VOLUNTEERS. Pharmacological Research 40:4, pages 351-356.
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Benedetta Reinach, Georges de Sousa, Philippe Dostert, Robert Ings, Jean Gugenheim & Roger Rahmani. (1999) Comparative effects of rifabutin and rifampicin on cytochromes P450 and UDP-glucuronosyl-transferases expression in fresh and cryopreserved human hepatocytes. Chemico-Biological Interactions 121:1, pages 37-48.
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Marc LeBel, Eric Masson, Edith Guilbert, Dave Colborn, Francois Paquet, Sylvie Allard, François Vallée & Prem K. Narang. (2013) Effects of Rifabutin and Rifampicin on the Pharmacokinetics of Ethinylestradiol and Norethindrone. The Journal of Clinical Pharmacology 38:11, pages 1042-1050.
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Glen Apseloff, George Foulds, Lucia LaBoy‐Goral, Susan Willavize & John Vincent. (2013) Comparison of Azithromycin and Clarithromycin in Their Interactions with Rifabutin in Healthy Volunteers. The Journal of Clinical Pharmacology 38:9, pages 830-835.
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Allen Cato, John Cavanaugh, Harry Shi, Ann Hsu, John Leonard & Richard Granneman. (1998) The effect of multiple doses of ritonavir on the pharmacokinetics of rifabutin*. Clinical Pharmacology & Therapeutics 63:4, pages 414-421.
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R C Li, P K Narang, J Sahai, W Cameron & J R Bianchine. (1997) Rifabutin absorption in the gut unaltered by concomitant administration of didanosine in AIDS patients. Antimicrobial Agents and Chemotherapy 41:7, pages 1566-1570.
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Marie T Borin, James H Chambers, Barbara J Carel, William W Freimuth, Sophia Aksentijevich & Antoni A Piergies. (1997) Pharmacokinetic study of the interaction between rifabutin and delavirdine mesylate in HIV-1 infected patients. Antiviral Research 35:1, pages 53-63.
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C B Trapnell, C Jamis-Dow, R W Klecker & J M Collins. (1997) Metabolism of rifabutin and its 25-desacetyl metabolite, LM565, by human liver microsomes and recombinant human cytochrome P-450 3A4: relevance to clinical interaction with fluconazole. Antimicrobial Agents and Chemotherapy 41:5, pages 924-926.
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Eugenia Iatsimirskaia, Samir Tulebaev, Elena Storozhuk, Ilya Utkin, Douglas Smith, Nicholas Gerber & Tatiana Koudriakova. (1997) Metabolism of rifabutin in human enterocyte and liver microsomes: Kinetic parameters, identification of enzyme systems, and drug interactions with macrolides and antifungal agents*. Clinical Pharmacology & Therapeutics 61:5, pages 554-562.
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Helga Bartels & Rainer Bartels. (1996) Determination of rifabutin by high-performance liquid chromatography using on-line concentration and column switching. Journal of Chromatography B: Biomedical Sciences and Applications 686:2, pages 235-240.
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R C LiS NightingaleR C LewisD C ColbornP K Narang. (1996) Lack of effect of concomitant zidovudine on rifabutin kinetics in patients with AIDS-related complex. Antimicrobial Agents and Chemotherapy 40:6, pages 1397-1402.
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M Strolin BenedettiP Dostert. (1994) Induction and autoinduction properties of rifamycin derivatives: a review of animal and human studies.. Environmental Health Perspectives 102:suppl 9, pages 101-105.
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Daniel S. Maddix, Kimberly B. Tallian & Paul S. Mead. (2016) Rifabutin: A Review with Emphasis on its Role in the Prevention of Disseminated Mycobacterium Avium Complex Infection . Annals of Pharmacotherapy 28:11, pages 1250-1254.
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L.J. Gonzalez-Montaner, S. Natal, P. Yongchaiyud, P. Olliaro, E. Abbate, C. Mosca, G. Casado, M. Di Lonardo, G. Gerhart-Filho, I. Betjel, S. Ferreira-Lima, A.Pereira Narinho, R. Lopez, A. Carlos-Moreira, A. Santana, A.Cruz Filho, M. Magahaes, A. Marinho, N. Cavabarra-Cardoso, R. Branao-Montero, B. Prijanonda, C. Nuchprayoon, J. Punnotok, T. Chakorn, M. Carpentieri, L. Dolfi & A. Maniero. (1994) Rifabutin for the treatment of newly-diagnosed pulmonary tuberculosis: a multinational, randomized, comparative study versus rifampicin. Tubercle and Lung Disease 75:5, pages 341-347.
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David E. Martin & Ralph H. Raasch. (2016) Rifabutin: A New Rifamycin for the Prevention of Atypical Mycobacterial Infection. Journal of Pharmacy Technology 10:5, pages 197-203.
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Margitta Albinus, Gudrun Amschler, Uwe Amschler, Erwin von Angerer, Wolfgang Barthel, Andrea Bauer, Kurt Bauer, Jürgen Beckmann, Winfried Beil, Jürgen Beitz, Petra Berscht, Thorsten Beyrich, Katja Binder, Roswitha Böhme, Hans-Hubertus Borchert, Franz Bracher, Helmut Bräunlich, Kerstin Brinkmann, Franz von Bruchhausen, Kay Brune, Axel Büge, Wolfram Christ, Monika Cimbollek, Rolf Daniels, Gerd Dannhardt, Hans-Jürgen Duchstein, Siegfried Ebel, Kurt Eger, Peter Emig, Thomas Erker, Maria S. Fernandez-Alfonso, August Wilhelm Frahm, Margarete Frahm, Klaus-Jürgen Freundt, Detlef Geffken, Ulrich Geis, Erika Glusa, Berthold Göber, Jochen Gödicke, Margarete Goppelt-Strübe, Wilhelm Gössling, Annette Graul, Sibylle Greiner, Adolf Grisk, Michael Grosam, Markus von Gruchalla, Michael Gütschow, Axel Haberkorn, Eberhard Hackenthal, Annette Häfner, Boris Haluszczynski, Achim Harder, Sabine Hartmann, Susanne Hartmann, Dieter Heber, Gerhard Heinemeyer, Andreas Hensel, Sibylle Hoedt-Schmidt, Hermann Hoffmann, Ute Hoffmann-Schollmayer, Ulrike Holzgrabe, Martin Hug, Wolfgang Ibrom, Elisabeth Inkmann, Jens Jürgens, Brigitte Kaiser, Dieter-Abbo Kalbhen, Nasser Khudeir, Werner Kiefer, Doris Kleinsorge, Christoph Klett, Stephanie Klett, Martin Klingmüller, H.-P. Klöcking, Gerd Kobal, Axel Kramer, Mareta Kreher, Gottfried Kreutz, Reinhard Kroker, Dorothea Landsiedel-Maier, Jochen Lehmann, Marion Sylvia Lehner, Stefan Leiner, Hans Löwe, Johannes Mann, Detlef Manns, Wolfgang Matthiessen, Andreas Maurer, Wolfgang Meindl, Klaus Menges, Paul Messinger, Hans-Jürgen Mest, Frank Peter Meyer, J. Mollière, Rudolf Morgenstern, Wolfgang Morick, Joachim Mössner, Christa Müller, Daniel Müller, Klaus Müller, Walter Müller, Alexander Mülsch, Tilo Netzer, Michael Neugebauer, Ulf Niemeyer, Peter Nuhn, Bernd Nürnberg, Joachim Oertel, Michael Oettel, Hartmut Oßwald, Robert Ott, Tilmann Ott, Thomas Otzen, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Martina Pickert, Andreas Pies, Klaus Pietrzik, Detlef Preiss, Helmut Priewer, Olaf Queckenberg, Eberhard Reimann, Jörg Remien, Rainer Rettig, Andreas Reymann, Joachim Richter, Hans Rommelspacher, Ulrich Rose, Gerhard Rücker, Klaus Schaefer, Helmut Schlager, Werner Schleicher, Hildegard Schleinitz, Wolfgang Schlichter, Helmut Schmidhammer, Gerhard Schmidt, Timo Schmidt, Johannes Schräder, Thomas Schulz, Gert Schulze, Peter Schwanz, Helmut Schwilden, Monika Serke, Gisela Skopp, Marcus Spohn, Ralf Stahlmann, Johannes-Peter Stasch, Christian Steffen, Jürgen Steinmeyer, Karl-Heinz Surborg, Ulf Sürig, Istvan Szelenyi, Reinhard Troschütz, Michael Verborg, Eugen J. Verspohl, Franz-Josef Volk, Heinz Walther, Horst Weber, Judith Wede, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Hilke Winterhoff, Reinhold Wintersteiger, Frauke Woltmann, Diaa Youssef & A. Ziegler. 1994. Hagers Handbuch der Pharmazeutischen Praxis. Hagers Handbuch der Pharmazeutischen Praxis 485 543 .
S.L. Chan, W.W. Yew, W.K. Ma, D.J. Girling, V.R. Aber, D. Felmingham, B.W. Allen & D.A. Mitchison. (1992) The early bactericidal activity of rifabutin measured by sputum viable counts in Hong Kong patients with pulmonary tuberculosis. Tubercle and Lung Disease 73:1, pages 33-38.
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M. Breda, E. Pianezzola, M. Strolin Benedetti, C. Efthymiopoulos, M. Carpentieri, D. Sassella & R. Rimoldi. (1992) A STUDY OF THE EFFECTS OF RIFABUTIN ON ISONIAZID PHARMACOKINETICS AND METABOLISM IN HEALTHY VOLUNTEERS. Drug Metabolism and Drug Interactions 10:4.
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