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Xenobiotica
the fate of foreign compounds in biological systems
Volume 20, 1990 - Issue 3
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Original Article

The mechanism of aphidicolin bioinactivation by rat liver in vitro systems

R. E. Edelson Department of Chemistry, University of Virginia, McCormick Road, Charlottesville, VA, 22901, USA
,
P. D. Gorycki Department of Chemistry, University of Virginia, McCormick Road, Charlottesville, VA, 22901, USA
&
T. L. Macdonald Department of Chemistry, University of Virginia, McCormick Road, Charlottesville, VA, 22901, USA
Pages 273-287 | Received 31 May 1989, Accepted 02 Oct 1989, Published online: 27 Aug 2009

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Monika Höltje, Anja Richartz, Barbara Zdrazil, Anja Schwanke, Branislav Dugovic, Caterina Murruzzu, Hans-Ulrich Reißig, Hans Christian Korting, Burkhard Kleuser, Hans-Dieter Höltje & Monika Schäfer-Korting. (2010) Human polymerase α inhibitors for skin tumors. Part 2. Modeling, synthesis and influence on normal and transformed keratinocytes of new thymidine and purine derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry 25:2, pages 250-265.
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Articles from other publishers (10)

Eva Bínová, David Bína & Eva Nohýnková. (2021) DNA content in Acanthamoeba during two stress defense reactions: Encystation, pseudocyst formation and cell cycle. European Journal of Protistology 77, pages 125745.
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Siwen Niu, Jin-Mei Xia, Zengpeng Li, Long-He Yang, Zhi-Wei Yi, Chun-Lan Xie, Guizhen Peng, Zhu-Hua Luo, Zongze Shao & Xian-Wen Yang. (2019) Aphidicolin Chemistry of the Deep-Sea-Derived Fungus Botryotinia fuckeliana MCCC 3A00494 . Journal of Natural Products 82:8, pages 2307-2331.
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James R. Hanson. (2018) Aphidicolin: Its Chemistry and Biosynthesis. Journal of Chemical Research 42:8, pages 395-401.
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Eva Vesela, Katarina Chroma, Zsofia Turi & Martin Mistrik. (2017) Common Chemical Inductors of Replication Stress: Focus on Cell‐Based Studies. Biomolecules 7:4, pages 19.
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Ting Han, Maria Goralski, Emanuela Capota, Shae B Padrick, Jiwoong Kim, Yang Xie & Deepak Nijhawan. (2016) The antitumor toxin CD437 is a direct inhibitor of DNA polymerase α. Nature Chemical Biology 12:7, pages 511-515.
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Andrey G. Baranovskiy, Nigar D. Babayeva, Yoshiaki Suwa, Jianyou Gu, Youri I. Pavlov & Tahir H. Tahirov. (2014) Structural basis for inhibition of DNA replication by aphidicolin. Nucleic Acids Research 42:22, pages 14013-14021.
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Alexey Yu. Nyporko. 2014. Application of Computational Techniques in Pharmacy and Medicine. Application of Computational Techniques in Pharmacy and Medicine 95 135 .
C. Jagger, M. Tate, P. A. Cahill, C. Hughes, A. W. Knight, N. Billinton & R. M. Walmsley. (2008) Assessment of the genotoxicity of S9-generated metabolites using the GreenScreen HC GADD45a-GFP assay. Mutagenesis 24:1, pages 35-50.
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E. Davoli, M. Zucchetti, M. D'Incalci, C. Sessa, F. Cavalli & R. Fanelli. (1993) Mass spectrometric identification and analysis of some aphidicolin metabolites in cancer patients. Biological Mass Spectrometry 22:6, pages 351-357.
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James R. Hanson, Peter B. Hitchcock, Andrew G. Jarvis, Elsa M. Rodriguez-Perez & Arnold H. Ratcliffe. (1992) Aphidicolane metabolites of Cephalosporium aphidicola. Phytochemistry 31:3, pages 799-803.
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