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Xenobiotica
the fate of foreign compounds in biological systems
Volume 20, 1990 - Issue 5
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Original Article

Age-related changes in biotransformation of azoxymethane and methylazoxymethanol in vitro

T. F. McMahon Department of Pharmacology and Toxicology, University of Maryland at Baltimore, Baltimore, MD, USA; Experimental Toxicology Branch, N1EHS, PO Box 12233, MD C3-02, Research Triangle ParkNC, 27709
,
J. O. Peggins Department of Pharmacology and Toxicology, University of Maryland at Baltimore, Baltimore, MD, USA
,
M. M. Centra Department of Pharmacology and Toxicology, University of Maryland at Baltimore, Baltimore, MD, USA
&
M. Weiner Department of Pharmacology and Toxicology, University of Maryland at Baltimore, Baltimore, MD, USA
Pages 501-513 | Received 10 Nov 1988, Accepted 20 Dec 1989, Published online: 27 Aug 2009

Citations (8)

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Zhi‐Ying Zheng & Carol Bernstein. (1992) Bile salt/acid induction of DNA damage in bacterial cells: Effect of taurine conjugation. Nutrition and Cancer 18:2, pages 157-164.
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RisaL. Kandell & Carol Bernstein. (1991) Bile salt/acid induction of DNA damage in bacterial and mammalian cells: Implications for colon cancer. Nutrition and Cancer 16:3-4, pages 227-238.
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Articles from other publishers (6)

Martina Perše & Anton Cerar. (2011) Morphological and Molecular Alterations in 1,2 Dimethylhydrazine and Azoxymethane Induced Colon Carcinogenesis in Rats. Journal of Biomedicine and Biotechnology 2011, pages 1-14.
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H. Chung, D. Wu, R. Gay, S. N. Han, B. Goldin, R. Bronson, J. Mason, D. E. Smith & S. N. Meydani. (2003) Effect of Age on Susceptibility to Azoxymethane-Induced Colonic Aberrant Crypt Foci Formation in C57BL/6JNIA Mice. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 58:5, pages B400-B405.
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J.H Exon & E.H South. (2003) Effects of sphingomyelin on aberrant colonic crypt foci development, colon crypt cell proliferation and immune function in an aging rat tumor model. Food and Chemical Toxicology 41:4, pages 471-476.
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W. Klinger. (1996) Biotransformation of Drugs and other Xenobiotics during Postnatal development. Experimental and Toxicologic Pathology 48, pages 1-88.
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L. S. Birnbaum. 1993. Cytochrome P450. Cytochrome P450 477 492 .
R. V. Gorenkov, P. N. Lyubchenko, É. A. Bendikov, V. B. Potapova, A. V. Petrakov & V. V. Ul'yanova. (1992) Antipyrin metabolism and hepatic ultrastructure of rats during isolated and combined exposure to trichlorodiphenyl and dioctyl phthalate. Bulletin of Experimental Biology and Medicine 113:3, pages 370-374.
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