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Xenobiotica
the fate of foreign compounds in biological systems
Volume 20, 1990 - Issue 5
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Original Article

The use of single sample clearance estimates to probe hepatic drug metabolism: handprinting the influence of cigarette smoking on human hepatic drug metabolism

K. A. Bachmann Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, Ohio, 43606, USA
,
M. Nunlee Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, Ohio, 43606, USA
,
M. Martin The Department of Pathology, Medical College of Ohio, Toledo, Ohio, 43606, USA
,
J. Schwartz St. Vincent Medical Center, Toledo, Ohio, 43606, USA
,
L. Jauregui St. Vincent Medical Center, Toledo, Ohio, 43606, USA
&
R. B. Forney The Department of Pathology, Medical College of Ohio, Toledo, Ohio, 43606, USA
Pages 537-547 | Received 01 Aug 1989, Accepted 20 Dec 1989, Published online: 27 Aug 2009

Citations (5)

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Read on this site (3)

K. A. Bachmann & L. Jauregui. (1993) Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo. Xenobiotica 23:3, pages 307-315.
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K. A. Bachmann, M. S. Madhira & G. O. Rankin. (1992) The effects of cobalt chloride, SKF-525A, and N-(3,5-dichlorophenyl)succinimide on in vivo hepatic mixed function oxidase activity as determined by single-sample plasma clearances. Xenobiotica 22:1, pages 27-31.
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K. A. Bachmann, M. Nunlee, M. Martin & L. Jaregui. (1991) The use of single sample clearance estimates to probe hepatic drug metabolism: Handprinting the influence of phenobarbitone on human hepatic drug metabolism. Xenobiotica 21:10, pages 1385-1392.
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Articles from other publishers (2)

O. Pelkonen & D. D. Breimer. 1994. Pharmacokinetics of Drugs. Pharmacokinetics of Drugs 289 332 .
S. WANWIMOLRUK, S. M. WONG, P. F. COVILLE, S. VIRIYAYUDHAKORN & S. THITIARCHAKUL. (1993) Cigarette smoking enhances the elimination of quinine. British Journal of Clinical Pharmacology 36:6, pages 610-614.
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