Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 20, 1990 - Issue 8
30
Views
8
CrossRef citations to date
0
Altmetric
Original Article

Absorption, distribution and excretion of lacidipine, a dihydropyridine calcium antagonist, in rat and dog

, , , &
Pages 765-777 | Received 08 Sep 1989, Accepted 07 Mar 1990, Published online: 27 Aug 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

P. Grossi, M. Pellegatti, G. Vigelli, J. Ayrton, B. A. Duncan & J. Maltas. (1992) Lacidipine metabolism in rat and dog: identification and synthesis of main metabolites. Xenobiotica 22:8, pages 899-916.
Read now

Articles from other publishers (7)

Qiang Fu, Bo Li, Dong Zhang, Mingming Fang, Jingbo Shao, Mengran Guo, Zhibin Guo, Mo Li, Jin Sun & Yinglei Zhai. (2015) Comparative studies of the in vitro dissolution and in vivo pharmacokinetics for different formulation strategies (solid dispersion, micronization, and nanocrystals) for poorly water-soluble drugs: A case study for lacidipine. Colloids and Surfaces B: Biointerfaces 132, pages 171-176.
Crossref
Chunnuan Wu, Longfa Kou, Panqin Ma, Lifang Gao, Bo Li, Ran Li, Cong Luo, Jianzhong Shentu, Zhonggui He & Jin Sun. (2015) Interspecies prediction of oral pharmacokinetics of different lacidipine formulations from dogs to human: physiologically based pharmacokinetic modelling combined with biorelevant dissolution. RSC Advances 5:26, pages 19844-19852.
Crossref
Shahab Bohlooli, Fariborz Keyhanfar & Massoud Mahmoudian. (2004) Pharmacokinetics of mebudipine, a new calcium antagonist, following single intravenous and oral administrations in rats. Biopharmaceutics & Drug Disposition 25:4, pages 187-191.
Crossref
Toshihiro Wajima, Kazuya Fukumura, Yoshitaka Yano & Takayoshi Oguma. (2003) Prediction of Human Pharmacokinetics from Animal Data and Molecular Structural Parameters using Multivariate Regression Analysis: Oral Clearance. Journal of Pharmaceutical Sciences 92:12, pages 2427-2440.
Crossref
Yuan H Zhao, Michael H Abraham, Joelle Le, Anne Hersey, Chris N Luscombe, Gordon Beck, Brad Sherborne & Ian Cooper. (2003) Evaluation of rat intestinal absorption data and correlation with human intestinal absorption. European Journal of Medicinal Chemistry 38:3, pages 233-243.
Crossref
F. Bernini, M. Canavesi, E. Bernardini, N. Scurati, S. Bellosta & R. Fumagalli. (2009) Effect of lacidipine on cholesterol esterification: in vivo and in vitro studies . British Journal of Pharmacology 122:6, pages 1209-1215.
Crossref
M. Pellegatti, S. Braggio, S. Sartori, F. Franceschetti & G.F. Bolelli. (1992) Validation of a high-performance liquid chromatographic—radioimmunoassay method for the determination of lacidipine in plasma. Journal of Chromatography B: Biomedical Sciences and Applications 573:1, pages 105-111.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.