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Xenobiotica
the fate of foreign compounds in biological systems
Volume 20, 1990 - Issue 2
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Research Article

The stereoselectivity of 1,2-phenylethanediol and mandelic acid metabolism and disposition in the rat

L. Drummond Health and Safety Executive, Occupational Medicine and Hygiene Laboratories, 403 Edgware Road, London, NW2 6LN, UK
,
J. Caldwell Department of Pharmacology and Toxicology, St Mary's Hospital Medical School, Norfolk Place, London, W2 1PG, UK
&
H. K. Wilson Health and Safety Executive, Occupational Medicine and Hygiene Laboratories, 403 Edgware Road, London, NW2 6LN, UK
Pages 159-168 | Received 08 Mar 1989, Accepted 14 Sep 1989, Published online: 22 Sep 2008

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T. NAITOH, S. KAWAGUCHI, M. KAKIKI, H. OHE, A. KAJIWARA & T. HORIE. (1998) Species differences and mechanism of the epimerization of a new MAO-A inhibitor. Xenobiotica 28:3, pages 269-280.
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I.F. Mao, M.L. Chen & E.W. Lo. (1996) Simultaneous Determination of Urinary Metabolites of Toluene, Xylene, Styrene and Ethyl Benzene by Solid-Phase Extraction Technique and High-Performance Liquid Chromatographic/Photo Diode Array Detection. International Journal of Environmental Analytical Chemistry 64:1, pages 1-9.
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Susan Jenkins Sumner & Timothy R. Fennell. (1994) Review of the Metabolic Fate of Styrene. Critical Reviews in Toxicology 24:sup1, pages S11-S33.
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Articles from other publishers (20)

Otsile O. Mojanaga, K. Ravi Acharya & Matthew D. Lloyd. 2023. Modern Methods of Drug Design and Development. Modern Methods of Drug Design and Development 1 37 .
Fuxin Chen, Qiaoxiu Bai, Qingfeng Wang, Suying Chen, Xiaoxian Ma, Changlong Cai, Danni Wang, Ahsan Waqas & Pin Gong. (2020) Stereoselective Pharmacokinetics and Chiral Inversions of Some Chiral Hydroxy Group Drugs. Current Pharmaceutical Biotechnology 21:15, pages 1632-1644.
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Yang Zhang, Chen Su, Jinxiu Lei, Lu Chen, Haihong Hu, Su Zeng & Lushan Yu. (2019) Studies on the L-2-hydroxy-acid oxidase 2 catalyzed metabolism of S-mandelic acid and its analogues. Drug Metabolism and Pharmacokinetics 34:3, pages 187-193.
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Prantu Dutta, Pranjal Kalita & Pranjal K. Baruah. (2016) Room Temperature Ring Opening of Epoxides Over Triflic Acid Functionalized Cage Like Mesoporous Materials. ChemistrySelect 1:8, pages 1650-1657.
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Maksims Yevglevskis, Catherine R. Bowskill, Chloe C. Y. Chan, Justin H.-J. Heng, Michael D. Threadgill, Timothy J. Woodman & Matthew D. Lloyd. (2014) A study on the chiral inversion of mandelic acid in humans. Org. Biomol. Chem. 12:34, pages 6737-6744.
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Claudio Bruno, Giovanni Lentini, Angelo Lovece, Maria Maddalena Cavalluzzi, Alessia Carocci, Alessia Catalano & Carlo Franchini. (2013) Microwave-Assisted Synthesis of -Mandelic Acid- , Optical Resolution, and Absolute Configuration Determination . Journal of Chemistry 2013, pages 1-6.
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Ling-Bo Gao, Jin-Zhao Wang, Tong-Wei Yao & Su Zeng. (2012) Study on the metabolic mechanism of chiral inversion of S-Mandelic acid in vitro. Chirality 24:1, pages 86-95.
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Sayantani Das & Tewodros Asefa. (2011) Epoxide Ring-Opening Reactions with Mesoporous Silica-Supported Fe(III) Catalysts. ACS Catalysis 1:5, pages 502-510.
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Jin‐Zhao Wang, Xin‐Yan Lu, Na‐Ping Zhao, Yi‐Yu Cheng & Su Zeng. (2007) Simultaneous determination of phenylglyoxylic acid, mandelic acid, styrene glycol and hippuric acid in primary culture of rat hepatocytes incubate by high‐performance liquid chromatography. Biomedical Chromatography 21:5, pages 497-501.
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Xin Yan-Fei, Zhou Xiang-Jun, Lu Jie & Wang Yong-Xiang. (2007) Inhibitory Effects of Benzoate on Chiral Inversion and Clearance of N G -Nitro-Arginine in Conscious Rats . Drug Metabolism and Disposition 35:3, pages 331-334.
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Li Cao, Jintae Lee, Wilfred Chen & Thomas K. Wood. (2006) Enantioconvergent production of ( R )‐1‐phenyl‐1,2‐ethanediol from styrene oxide by combining the Solanum tuberosum and an evolved Agrobacterium radiobacter AD1 epoxide hydrolases . Biotechnology and Bioengineering 94:3, pages 522-529.
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Yan-Fei Xin, Xiang-Jun Zhou, Xi Cheng & Yong-Xiang Wang. (2005) Renal d-Amino Acid Oxidase Mediates Chiral Inversion of N G -Nitro-d-arginine . Journal of Pharmacology and Experimental Therapeutics 312:3, pages 1090-1096.
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Neal Davies. 2004. Chirality in Drug Design and Development. Chirality in Drug Design and Development.
. (2001) Enantiomers and separation. Chromatographia 54:S1, pages S7-S14.
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Stephen WrenStephen Wren, T. A. Berger, K.-S. Boos, H. Engelhardt, E. R. Adlard, I. W. Davies, K. D. Altria & R. Stock. 2001. The Separation of Enantiomers by Capillary Electrophoresis. The Separation of Enantiomers by Capillary Electrophoresis 7 14 .
Yong-Xiang Wang, Xing Cheng & Catherine C.Y. Pang. (1999) Bilateral kidney ligation abolishes pressor response to NG-nitro-d-arginine. European Journal of Pharmacology 366:2-3, pages 175-179.
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D.B Matthews, R.H Hinton, B Wright, I.D Wilson & D Stevenson. (1997) Bioanalysis of p-trifluoromethylmandelic acid and Mosher's acid by chiral gas chromatography and fluorine nuclear magnetic resonance to study chiral inversion: application to rat urine samples. Journal of Chromatography B: Biomedical Sciences and Applications 695:2, pages 279-285.
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T Naitoh, M Kakiki, S Kawaguchi, Y Kagei & T Horie. (1997) Stereoselective determination of a new antidepressant, E2011, and its diastereoisomer as a metabolite by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 694:1, pages 153-161.
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Brian L. Goodwin, Colin R.J. Ruthven & Merton Sandler. (1997) Metabolism of phenylethanolamines and 2-oxo-2-phenylethylamines in the rat. General Pharmacology: The Vascular System 28:4, pages 535-543.
Crossref
John Caldwell. (1995) Stereochemical determinants of the nature and consequences of drug metabolism. Journal of Chromatography A 694:1, pages 39-48.
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