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Xenobiotica
the fate of foreign compounds in biological systems
Volume 20, 1990 - Issue 2
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Research Article

Human biliary metabolites of isotretinoin: identification, quantification, synthesis, and biological activity

F. M. Vane Research Division, Hoffmann-La Roche Inc., Nutley, NJ, 07110, USA
,
C. J. L. Bugge Research Division, Hoffmann-La Roche Inc., Nutley, NJ, 07110, USA; Radian Corporation, PO Box 9948, Austin, TX, 78766, USA
,
L. C. Rodriguez Research Division, Hoffmann-La Roche Inc., Nutley, NJ, 07110, USA; Sandoz Research Institute, Route 10E, Hanover, NJ, 07936, USA
,
M. Rosenberger Research Division, Hoffmann-La Roche Inc., Nutley, NJ, 07110, USA
&
T. I. Doran Research Division, Hoffmann-La Roche Inc., Nutley, NJ, 07110, USA
Pages 193-207 | Received 15 Mar 1989, Accepted 25 Jul 1989, Published online: 22 Sep 2008

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A. Treiber, P. L. M. Van Giersbergen & J. Dingemanse. (2003) In vivo and in vitro disposition profile of tezosentan, an intravenous dual endothelin receptor antagonist, in humans. Xenobiotica 33:4, pages 399-414.
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Donald L. Hill & Brahma P. Sani. (1991) Metabolic Disposition and Development of New Chemopreventive Retinoids. Drug Metabolism Reviews 23:3-4, pages 413-438.
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Articles from other publishers (10)

Nina Isoherranen & Guo Zhong. (2019) Biochemical and physiological importance of the CYP26 retinoic acid hydroxylases. Pharmacology & Therapeutics 204, pages 107400.
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Rana Mohsen Elewa & Christos C. Zouboulis. 2011. Nutrition and Skin. Nutrition and Skin 7 23 .
Anders Vahlquist. 2007. Retinoids and Carotenoids in Dermatology. Retinoids and Carotenoids in Dermatology 55 68 .
D. Belsito, D. Bickers, M. Bruze, P. Calow, H. Greim, J.M. Hanifin, A.E. Rogers, J.H. Saurat, I.G. Sipes & H. Tagami. (2007) A toxicologic and dermatologic assessment of ionones when used as fragrance ingredients. Food and Chemical Toxicology 45:1, pages S130-S167.
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Melih Akyol & Sedat ??z??elik. (2005) Non-Acne Dermatologic Indications for Systemic Isotretinoin. American Journal of Clinical Dermatology 6:3, pages 175-184.
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Carsten K Schmidt, Jutta Volland, Gerd Hamscher & Heinz Nau. (2002) Characterization of a new endogenous vitamin A metabolite. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1583:2, pages 237-251.
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T.B. Adams, J.B. Hallagan, J.M. Putnam, T.L. Gierke, J. Doull, I.C. Munro, P. Newberne, P.S. Portoghese, R.L. Smith, B.M. Wagner, C.S. Weil, L.A. Woods & R.A. Ford. (1996) The FEMA GRAS assessment of alicyclic substances used as flavour ingredients. Food and Chemical Toxicology 34:9, pages 763-828.
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. (1996) Clinical development plan: 13-cis-Retinoic acid. Journal of Cellular Biochemistry 63:S26, pages 168-201.
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Ronald Wyss. (1995) Chromatographic and electrophoretic analysis of biomedically important retinoids. Journal of Chromatography B: Biomedical Sciences and Applications 671:1-2, pages 381-425.
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Thomas I. Doran, Robin Baff, Pamela Jacobs & Emmanual Pacia. (1991) Characterization of Human Sebaceous Cells In Vitro. Journal of Investigative Dermatology 96:3, pages 341-348.
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