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Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 1
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Original Article

The in vitro uptake and metabolism of lignocaine, procainamide and pethidine by tissues of the hindquarters of sheep

R. N. Upton Department of Anaesthesia and Intensive Care, The Flinders University of South Australia, Flinders Medical Centre, Bedford Park, SA, 5042, Australia
,
L. E. Mather Department of Anaesthesia and Intensive Care, The Flinders University of South Australia, Flinders Medical Centre, Bedford Park, SA, 5042, Australia
&
W. B. Runciman Department of Anaesthesia and Intensive Care, The Flinders University of South Australia, Flinders Medical Centre, Bedford Park, SA, 5042, Australia
Pages 1-12 | Received 13 Nov 1989, Accepted 25 May 1990, Published online: 27 Aug 2009

Citations (6)

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R. N. Upton, C. Nancarrow, C. F. McLean, L. E. Mather & W. B. Runciman. (1991) The in vivo blood, fat and muscle concentrations of lignocaine and bupivacaine in the hindquarters of sheep. Xenobiotica 21:1, pages 13-22.
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Articles from other publishers (5)

Yoo-Seong Jeong & William J Jusko. (2023) A Complete Extension of Classical Hepatic Clearance Models Using Fractional Distribution Parameter in Physiologically Based Pharmacokinetics . Journal of Pharmaceutical Sciences.
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Kathleen M. Antony, Jacquelyn H. Adams, Laura Jacques, Scott Hetzel, Richard J. Chappell, Sarah E. Gnadt & Amye J. Tevaarwerk. (2021) Lidocaine patches for postcesarean pain control in obese women: a pilot randomized controlled trial. American Journal of Obstetrics & Gynecology MFM 3:1, pages 100281.
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Laurence E. Mather. (2001) Anatomical-Physiological Approaches in Pharmacokinetics and Pharmacodynamics. Clinical Pharmacokinetics 40:10, pages 707-722.
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Raquel F. Reinoso, Brian A. Telfer & Malcolm Rowland. (2000) Use of a single-pass in situ perfused rat hindlimb to study tissue distribution kinetics. Journal of Pharmacological and Toxicological Methods 43:3, pages 191-198.
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Anne C. Heatherington & Malcolm Rowland. (1994) Estimation of reference space in the perfused rat hindlimb. European Journal of Pharmaceutical Sciences 2:4, pages 261-270.
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