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Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 1
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Original Article

The in vivo blood, fat and muscle concentrations of lignocaine and bupivacaine in the hindquarters of sheep

R. N. Upton Department of Anaesthesia and Intensive Care, The Flinders University of South Australia, Flinders Medical Centre, Bedford Park, SA, 5042, Australia
,
C. Nancarrow Department of Anaesthesia and Intensive Care, The Flinders University of South Australia, Flinders Medical Centre, Bedford Park, SA, 5042, Australia
,
C. F. McLean Department of Anaesthesia and Intensive Care, The Flinders University of South Australia, Flinders Medical Centre, Bedford Park, SA, 5042, Australia
,
L. E. Mather Department of Anaesthesia and Intensive Care, The Flinders University of South Australia, Flinders Medical Centre, Bedford Park, SA, 5042, Australia
&
W. B. Runciman Department of Anaesthesia and Intensive Care, The Flinders University of South Australia, Flinders Medical Centre, Bedford Park, SA, 5042, Australia
Pages 13-22 | Received 13 Nov 1989, Accepted 30 Jul 1990, Published online: 27 Aug 2009

Citations (14)

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R. N. Upton, L. E. Mather & W. B. Runciman. (1991) The in vitro uptake and metabolism of lignocaine, procainamide and pethidine by tissues of the hindquarters of sheep. Xenobiotica 21:1, pages 1-12.
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Articles from other publishers (13)

Kathleen M. Antony, Jacquelyn H. Adams, Laura Jacques, Scott Hetzel, Richard J. Chappell, Sarah E. Gnadt & Amye J. Tevaarwerk. (2021) Lidocaine patches for postcesarean pain control in obese women: a pilot randomized controlled trial. American Journal of Obstetrics & Gynecology MFM 3:1, pages 100281.
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Krysta L. Martin, Maaike O. Clapham, Jennifer L. Davis, Ronald E. Baynes, Zhoumeng Lin, Thomas W. Vickroy, Jim E. Riviere & Lisa A. Tell. (2018) Extralabel drug use in small ruminants. Journal of the American Veterinary Medical Association 253:8, pages 1001-1009.
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Susan E. Copeland, Leigh A. Ladd, Xiao-Qing Gu & Laurence E. Mather. (2008) The Effects of General Anesthesia on Whole Body and Regional Pharmacokinetics of Local Anesthetics at Toxic Doses. Anesthesia & Analgesia 106:5, pages 1440-1449.
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Laurence E. Mather. (2001) Anatomical-Physiological Approaches in Pharmacokinetics and Pharmacodynamics. Clinical Pharmacokinetics 40:10, pages 707-722.
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Raquel F. Reinoso, Brian A. Telfer & Malcolm Rowland. (2000) Use of a single-pass in situ perfused rat hindlimb to study tissue distribution kinetics. Journal of Pharmacological and Toxicological Methods 43:3, pages 191-198.
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Laurence E. Mather, Yi Fei Huang, Bernadette Veering & Marie E. Pryor. (1998) Systemic and Regional Pharmacokinetics of Levobupivacaine and Bupivacaine Enantiomers in Sheep. Anesthesia & Analgesia 86:4, pages 805-811.
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Laurence E. Mather, Yi Fei Huang, Bernadette Veering & Marie E. Pryor. (1998) Systemic and Regional Pharmacokinetics of Levobupivacaine and Bupivacaine Enantiomers in Sheep. Anesthesia & Analgesia 86:4, pages 805-811.
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Anne C. Heatherington & Malcolm Rowland. (1995) Discrepancies in pharmacokinetic parameter estimation between bolus and infusion studies in the perfused rat hindlimb. Journal of Pharmacokinetics and Biopharmaceutics 23:5, pages 441-462.
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Laurence E. Mather, Peter McCall & P. Larry McNicol. (1995) Bupivacaine Enantiomer Pharmacokinetics After Intercostal Neural Blockade in Liver Transplantation Patients. Anesthesia & Analgesia 80:2, pages 328-335.
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Laurence E. Mather, Peter McCall & P. Larry McNicol. (1995) Bupivacaine Enantiomer Pharmacokinetics After Intercostal Neural Blockade in Liver Transplantation Patients. Anesthesia & Analgesia 80:2, pages 328-335.
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Anne C. Heatherington & Malcolm Rowland. (1994) Estimation of reference space in the perfused rat hindlimb. European Journal of Pharmaceutical Sciences 2:4, pages 261-270.
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Richard N. Upton. (1994) An analysis of errors arising from the direct use of mass balance principles to describe regional drug uptake and elution. Journal of Pharmacokinetics and Biopharmaceutics 22:4, pages 309-321.
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Parminder Singh & Michael S. Roberts. (1994) Dermal and Underlying Tissue Pharmacokinetics of Lidocaine after topical application. Journal of Pharmaceutical Sciences 83:6, pages 774-782.
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