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Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 1
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Original Article

Metronidazole and antipyrine metabolism in the rat: Clearance determination from one saliva sample

S. Loft Department of Pharmacology, University of Copenhagen, Denmark
,
A. J. Nielsen Department of Pharmacology, University of Copenhagen, Denmark
,
B. E. Borg Department of Pharmacology, University of Copenhagen, Denmark
&
H. E. Poulsen Department of Pharmacology, University of Copenhagen, Denmark
Pages 33-46 | Received 07 Jan 1990, Accepted 22 Jun 1990, Published online: 27 Aug 2009

Citations (8)

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I. B. Jeding, S. Loft & H. E. Poulsen. (1993) Non-induction of extrahepatic antipyrine and metronidazole metabolism evaluated from partially hepatectomized rats. Xenobiotica 23:4, pages 411-418.
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Articles from other publishers (7)

Mankes Russell F & Silver Charles D. (2016) Hospital Antibiotic Wasting and Evaluation of Potential Ecologic Effects. Annals of Environmental Science and Toxicology 1:1, pages 012-022.
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L. J LANGMAN. (2007) The Use of Oral Fluid for Therapeutic Drug Management: Clinical and Forensic Toxicology. Annals of the New York Academy of Sciences 1098:1, pages 145-166.
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W. CYBULSKI, P. LARSSON, H. TJÄLVE, H. KOWALSKA‐PYLKA, M. SYLLA & S. SEMENIUK. (2008) Disposition of metronidazole in hens (Gallus gallus) and quails (Coturnix coturnix japonica) : pharmacokinetics and whole‐body autoradiography . Journal of Veterinary Pharmacology and Therapeutics 19:5, pages 352-358.
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IVENS A. SIEGEL. (1993) The Role of Saliva in Drug Monitoring. Annals of the New York Academy of Sciences 694:1 Saliva as a D, pages 86-90.
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Gilbert O. Kokwaro, Sabariah Ismail, Anthony P. Glazier, Stephen A. Ward & Geoffrey Edwards. (1993) Effect of malaria infection and endotoxin-induced fever on the metabolism of antipyrine and metronidazole in the rat. Biochemical Pharmacology 45:6, pages 1243-1249.
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S. Loft, J. Otte, H.E. Poulsen & H. Sørensen. (1992) Influence of intact and myrosinase-treated indolyl glucosinolates on the metabolism in vivo of metronidazole and antipyrine in the rat. Food and Chemical Toxicology 30:11, pages 927-935.
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Steffen Loft, Victoria Otton, Martin S. Lennard, Geoffrey T. Tucker & Henrik E. Poulsen. (1991) Characterization of metronidazole metabolism by human liver microsomes. Biochemical Pharmacology 41:8, pages 1127-1134.
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