Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 2
Submit an article Journal homepage
24
Views
14
CrossRef citations to date
0
Altmetric
Original Article

Human liver sulphotransferase and UDP-glucuronosyltransferase: Structure-activity relationship for phenolic substrates

A. Temellini Department of Experimental Biomedicine, Medical School, University of Pisa, 56100, Pisa, Italy
,
M. Franchi Department of Experimental Biomedicine, Medical School, University of Pisa, 56100, Pisa, Italy
,
L. Giuliani Department of Surgery, Medical School, University of Pisa, 56100, Pisa, Italy
&
G. M. Pacifici Department of Experimental Biomedicine, Medical School, University of Pisa, 56100, Pisa, Italy
Pages 171-177 | Received 14 Feb 1990, Accepted 10 Aug 1990, Published online: 27 Aug 2009

Citations (14)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

M. E. Bollard, E. Holmes, C. A. Blackledge, J. C. Lindon, I. D. Wilson & J. K. Nicholson. (1996) 1H and 19F-nmr spectroscopic studies on the metabolism and urinary excretion of mono- and disubstituted phenols in the rat. Xenobiotica 26:3, pages 255-273.
Read now
E. Holmes, B. C. Sweatman, M. E. Bollard, C. A. Blackledge, C. R. Beddell, I. D. Wilson, J. C. Lindon & J. K. Nicholson. (1995) Prediction of urinary sulphate and glucuronide conjugate excretion for substituted phenols in the rat using quantitative structure-metabolism relationships. Xenobiotica 25:12, pages 1269-1281.
Read now
J. Jodynis-Liebert. (1993) Metabolism of 1-(4-hydroxy-3-methoxyphenyl)-2-propanone, a smoke flavour ketone, in rat. Xenobiotica 23:6, pages 693-701.
Read now
G. M. Pacifici, L. Vannucci, C. Bencini, G. Tusini & F. Mosca. (1991) Sulphation of hydroxybiphenyls in human tissues. Xenobiotica 21:9, pages 1113-1118.
Read now

Articles from other publishers (10)

Kai Yang, Zhi-Wei Fu, Yun-Feng Cao, Sai-Nan Li, Zuo Du, Xiao-Yu Sun, Yong-Zhe Liu, Kun Yang & Zhong-Ze Fang. (2018) New insights for risks of chlorophenols (CPs) exposure: Inhibition of UDP-glucuronosyltransferases (UGTs). Chemosphere 206, pages 9-16.
Crossref
Jianlong Peng, Jing Lu, Qiancheng Shen, Mingyue Zheng, Xiaomin Luo, Weiliang Zhu, Hualiang Jiang & Kaixian Chen. (2014) In silico site of metabolism prediction for human UGT-catalyzed reactions . Bioinformatics 30:3, pages 398-405.
Crossref
P.A Smith, M.J Sorich, L.S.C Low, R.A McKinnon & J.O Miners. (2004) Towards integrated ADME prediction: past, present and future directions for modelling metabolism by UDP-glucuronosyltransferases. Journal of Molecular Graphics and Modelling 22:6, pages 507-517.
Crossref
Christel M. Olsen, Elise T. M. Meussen-Elholm, Mari Samuelsen, Jørn A. Holme & Jan K. Hongslo. (2003) Effects of the Environmental Oestrogens Bisphenol A, Tetrachlorobisphenol A, Tetrabromobisphenol A, 4-Hydroxybiphenyl and 4,4′-Dihydroxybiphenyl on Oestrogen Receptor Binding, Cell Proliferation and Regulation of Oestrogen Sensitive Proteins in the Human. Pharmacology & Toxicology 92:4, pages 180-188.
Crossref
Makiko Shimizu, Yoshiaki Matsumoto, Masahiro Tatsuno & Masamichi Fukuoka. (2003) Glucuronidation of Propofol and Its Analogs by Human and Rat Liver Microsomes.. Biological and Pharmaceutical Bulletin 26:2, pages 216-219.
Crossref
Sarvesh C. Vashishtha, Edward M. Hawes, Denis J. McCann, Omar Ghosheh & Lawrence Hogg. (2002) Quaternary Ammonium-Linked Glucuronidation of 1-Substituted Imidazoles by Liver Microsomes: Interspecies Differences and Structure-Metabolism Relationships. Drug Metabolism and Disposition 30:10, pages 1070-1076.
Crossref
Brian T. Ethell, Sean Ekins, Jibo Wang & Brian Burchell. (2002) Quantitative Structure Activity Relationships for the Glucuronidation of Simple Phenols by Expressed Human UGT1A6 and UGT1A9. Drug Metabolism and Disposition 30:6, pages 734-738.
Crossref
Corwin Hansch, David Hoekman, A. Leo, David Weininger & Cynthia D. Selassie. (2002) Chem-Bioinformatics:  Comparative QSAR at the Interface between Chemistry and Biology. Chemical Reviews 102:3, pages 783-812.
Crossref
GIAN MARIA PACIFICI & GIOVANNA MARCHI. (1993) Interindividual variability of phenol- and catechol-sulphotransferases in platelets from adults and newborns. British Journal of Clinical Pharmacology 36:6, pages 593-597.
Crossref
G. M. Pacifici, M. Eligi & L. Giuliani. (1993) (+) and (?) terbutaline are sulphated at a higher rate in human intestine than in liver. European Journal of Clinical Pharmacology 45:5, pages 483-487.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.