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Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 2
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Original Article

Cimetidine: An inhibitor and an inducer of rat liver microsomal cytochrome P-450

A. W. E. Wright Department of Biochemistry, University of Queensland, Queensland, 4072, Austalia
,
D. J. Winzor Department of Biochemistry, University of Queensland, Queensland, 4072, Austalia
&
P. E. B. Reilly Department of Biochemistry, University of Queensland, Queensland, 4072, Austalia
Pages 193-203 | Received 28 Feb 1990, Accepted 30 Jul 1990, Published online: 27 Aug 2009

Citations (6)

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Y.K. Leung & J.W. Ho. (2001) Effects of Vitamins and Common Drugs on Reduction of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone in Rat Microsomes. Archives of Physiology and Biochemistry 109:2, pages 175-179.
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Articles from other publishers (5)

S.Abolfazl Mostafavi & Robert T. Foster. (2003) Influence of cimetidine co-administration on the pharmacokinetics of acebutolol enantiomers and its metabolite diacetolol in a rat model: the effect of gastric pH on double-peak phenomena. International Journal of Pharmaceutics 255:1-2, pages 81-86.
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F Caballero, E Gerez, A Batlle & E Vazquez. (2002) Interaction of cimetidine with P450 in a mouse model of hepatocarcinogenesis initiation. British Journal of Cancer 86:4, pages 630-635.
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Orishiki Mitsuru, Matsuo Yoshinori, Nishioka Mikio & Ichikawa Yoshiyuki. (1994) In vivo administration of H2 blockers, cimetidine and ranitidine, reduced the contents of the cytochrome P450IID (CYP2D) subfamily and their activities in rat liver microsomes. International Journal of Biochemistry 26:6, pages 751-758.
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M.J. Seaton & E.S. Vesell. (1993) Variables affecting nicotine metabolism. Pharmacology & Therapeutics 60:3, pages 461-500.
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Julia H. Fentem & Jeffrey R. Fry. (1991) Effect of cimetidine on the metabolism of coumarin by rat, gerbil and human liver microsomes. Biochemical Pharmacology 42:7, pages 1508-1510.
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