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Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 3
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Research Article

Comparison of the rat liver microsomal metabolism of the enantiomers of warfarin and 4′-nitrowarfarin (Acenocoumarol)

J. J. R. Hermans Department of Pharmacology, University of Limburg, Maastricht, The Netherlands
&
H. H. W. Thijssen Department of Pharmacology, University of Limburg, Maastricht, The Netherlands
Pages 295-307 | Received 25 Jan 1990, Accepted 07 Sep 1990, Published online: 22 Sep 2008

Citations (11)

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J. Brian Houston & David J. Carlile. (1997) Prediction of Hepatic Clearance from Microsomes, Hepatocytes, and Liver Slices. Drug Metabolism Reviews 29:4, pages 891-922.
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Articles from other publishers (10)

Rianne M.F. van Schie, Talitha I. Verhoef, Anthonius de Boer, Felix J.M. van der Meer, William K. Redekop, Tom Schalekamp & Anke-Hilse Maitland-van der Zee. 2015. Preventive and Predictive Genetics: Towards Personalised Medicine. Preventive and Predictive Genetics: Towards Personalised Medicine 307 328 .
Anthony Long. (2013) Drug metabolism in silico – the knowledge-based expert system approach. Historical perspectives and current strategies. Drug Discovery Today: Technologies 10:1, pages e147-e153.
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Bernard Testa & Stefanie D. Krämer. (2007) The Biochemistry of Drug Metabolism – An Introduction. Chemistry & Biodiversity 4:3, pages 257-405.
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Mike Ufer. (2005) Comparative Pharmacokinetics of Vitamin K Antagonists. Clinical Pharmacokinetics 44:12, pages 1227-1246.
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Sarah J. Griffin & J. Brian Houston. (2004) COMPARISON OF FRESH AND CRYOPRESERVED RAT HEPATOCYTE SUSPENSIONS FOR THE PREDICTION OF IN VITRO INTRINSIC CLEARANCE. Drug Metabolism and Disposition 32:5, pages 552-558.
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S.A. SMITH, S.L. KRAFT, D.C. LEWIS & L.C. FREEMAN. (2008) Plasma pharmacokinetics of warfarin enantiomers in cats. Journal of Veterinary Pharmacology and Therapeutics 23:6, pages 329-337.
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S.A. SMITH, S.L. KRAFT, D.C. LEWIS & L.C. FREEMAN. (2000) Plasma pharmacokinetics of warfarin enantiomers in cats. Journal of Veterinary Pharmacology and Therapeutics 23:6, pages 329-337.
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J.J.R. Hermans & H.H.W. Thijssen. (1993) Human liver microsomal metabolism of the enantiomers of warfarin and acenocoumarol: P450 isozyme diversity determines the differences in their pharmacokinetics. British Journal of Pharmacology 110:1, pages 482-490.
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Eugène H.J.M. Jansen & P. de Fluiter. (1992) Detection of the enzymatic activity of cytochrome P-450 enzymes by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 580:1-2, pages 325-346.
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R.Scott Obach, David C. Spink, Norman Chen & Laurence S. Kaminsky. (1992) Azidowarfarin photoaffinity probes of purified rat liver cytochrome P4501A1. Archives of Biochemistry and Biophysics 294:1, pages 215-222.
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