Citations (34)
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Urs A. Boelsterli, Hyman J. Zimmerman & Anke Kretz-Rommel. (1995) Idiosyncratic Liver Toxicity of Nonsteroidal Antiinflammatory Drugs: Molecular Mechanisms and Pathology. Critical Reviews in Toxicology 25:3, pages 207-235.
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Hildegard Spahn Langguth & Leslie Z. Benet. (1992) Acyl Glucuronides Revisited: Is the Glucuronidation Proces a Toxification as Well as a Detoxification Mechanism?. Drug Metabolism Reviews 24:1, pages 5-47.
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R. G. Dickinson, R. K. Verbeeck & A. R. King. (1991) Absence of phenolic glucuronidation and enhanced hydroxylation of diflunisal in the homozygous Gunn rat. Xenobiotica 21:11, pages 1535-1546.
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Articles from other publishers (31)
Markus Walles, Alan P. Brown, Alfred Zimmerlin & Peter End. (2020) New Perspectives on Drug-Induced Liver Injury Risk Assessment of Acyl Glucuronides. Chemical Research in Toxicology 33:7, pages 1551-1560.
Crossref
Crossref
Urs A. Boelsterli. 2013. Drug-Induced Liver Disease. Drug-Induced Liver Disease
343
367
.
Howard Horng, Hilde Spahn-Langguth & Leslie Z. Benet. 2013. Drug-Induced Liver Disease. Drug-Induced Liver Disease
35
70
.
Hsiu-Ying Yu & Yu-Zen Shen. (2002) Concentration-dependent disposition of glucuronide metabolite of valproate. Journal of Pharmacy and Pharmacology 54:5, pages 633-639.
Crossref
Crossref
Bernard Testa & Stefanie D. Krämer. (2008) The Biochemistry of Drug Metabolism – An Introduction. Chemistry & Biodiversity 5:11, pages 2171-2336.
Crossref
Crossref
Kuniko Mitamura, Mitsuru Sogabe, Hironori Sakanashi, Saai Watanabe, Toshihiro Sakai, Yoshihiro Yamaguchi, Tateaki Wakamiya & Shigeo Ikegawa. (2007) Analysis of bile acid glutathione thioesters by liquid chromatography/electrospray ionization–tandem mass spectrometry. Journal of Chromatography B 855:1, pages 88-97.
Crossref
Crossref
Urs Boelsterli. 2007. Mechanistic Toxicology. Mechanistic Toxicology
63
116
.
. 2002. Handbook of Essential Pharmacokinetics, Pharmacodynamics and Drug Metabolism for Industrial Scientists. Handbook of Essential Pharmacokinetics, Pharmacodynamics and Drug Metabolism for Industrial Scientists
121
168
.
Shigeo Ikegawa, Ni Made Ria Isriyanthi, Masanori Nagata, Kenji Yahata, Hiromi Ito, Nariyasu Mano & Junichi Goto. (2001) The Enantioselective Immunoaffinity Extraction of an Optically Active Ibuprofen-Modified Peptide Fragment. Analytical Biochemistry 296:1, pages 63-72.
Crossref
Crossref
Philip Smith. 1999. Handbook of Drug Metabolism. Handbook of Drug Metabolism
1
47
.
Shigeo Ikegawa, Naoaki Murao, Junji Oohashi & Junichi Goto. (1998) Separatory determination of diastereomeric ibuprofen glucuronides in human urine by liquid chromatography/electrospray ionization-mass spectrometry. Biomedical Chromatography 12:6, pages 317-321.
Crossref
Crossref
Lynette C Kirkwood, Roger L Nation & Andrew A Somogyi*. (2008) GLUCURONIDATION OF DIHYDROCODEINE BY HUMAN LIVER MICROSOMES AND THE EFFECT OF INHIBITORS. Clinical and Experimental Pharmacology and Physiology 25:3‐4, pages 266-270.
Crossref
Crossref
Andreas Kirschning, Monika Ries, Silvie Domann, Wolfgang Martin, Wolfgang Albrecht, Peter Arnold & Stefan Laufer. (1997) Synthesis and biological identification of the acyl glucuronide of the antiinflammatory drug ML-3000. Bioorganic & Medicinal Chemistry Letters 7:7, pages 903-906.
Crossref
Crossref
Andrew R. King & Ronald G. Dickinson. (1996) The utility of the bile-exteriorized rat as a source of reactive acyl glucuronides: Studies with zomepirac. Journal of Pharmacological and Toxicological Methods 36:3, pages 131-136.
Crossref
Crossref
Ronald G. Dickinson & Andrew R. King. (2007) VESICO‐HEPATO‐RENAL CYCLING OF ACIDIC DRUGS VIA THEIR REACTIVE ACYL GLUCURONIDE METABOLITES? STUDIES WITH DIFLUNISAL IN RATS. Clinical and Experimental Pharmacology and Physiology 23:8, pages 665-668.
Crossref
Crossref
Simon Worrall & Ronald G. Dickinson. (1995) Rat serum albumin modified by diflunisal acyl glucuronide is emmunogenic in rats. Life Sciences 56:22, pages 1921-1930.
Crossref
Crossref
Adrienne M. Williams, Simon Worrall, John De Jersey & Ronald G. Dickinson. (1995) Studies on the reactivity of acyl glucuronides—VIII. Generation of an antiserum for the detection of diflunisal-modified proteins in diflunisal-dosed rats. Biochemical Pharmacology 49:2, pages 209-217.
Crossref
Crossref
Peter J. Hayball. (2004) Formation and reactivity of acyl glucuronides: The influence of chirality. Chirality 7:1, pages 1-9.
Crossref
Crossref
Adrienne M. Williams & Ronald G. Dickinson. (1994) Studies on the reactivity of acyl glucuronides—VI. Biochemical Pharmacology 47:3, pages 457-467.
Crossref
Crossref
Gary D. Bowers, Peter J. Eddershaw, Soraya Y. Hughes, Gary R. Manchee, Janet Oxford & D. E. Games. (2005) Characterization of glucuronic acid conjugates of a novel angiotensin receptor antagonist. Rapid Communications in Mass Spectrometry 8:2, pages 217-221.
Crossref
Crossref
M. Barjavel, P. Sandouk, M. Plotkine & J-M. Scherrmann. (1994) Morphine and morphine metabolite kinetics in the rat brain as assessed by transcortical microdialysis. Life Sciences 55:16, pages 1301-1308.
Crossref
Crossref
C. Fenselau. 1994. Conjugation—Deconjugation Reactions in Drug Metabolism and Toxicity. Conjugation—Deconjugation Reactions in Drug Metabolism and Toxicity
367
389
.
Haiyung Cheng & William J. Jusko. (2006) Pharmacokinetics of reversible metabolic systems. Biopharmaceutics & Drug Disposition 14:9, pages 721-766.
Crossref
Crossref
Ronald G. Dickinson & Andrew R. King. (1993) Studies on the reactivity of acyl glucuronides—V. Glucuronide-derived covalent binding of diflunisal to bladder tissue of rats and its modulation by urinary pH and β-glucuronidase. Biochemical Pharmacology 46:7, pages 1175-1182.
Crossref
Crossref
RG Dickinson, AR King, GE McKinnon, WD Hooper, MJ Eadie & GK Herkes. (2012) Studies on the renal excretion of the acyl glucuronide, phenolic glucuronide and sulphate conjugates of diflunisal.. British Journal of Clinical Pharmacology 35:6, pages 609-613.
Crossref
Crossref
Andrew R. King & Ronald G. Dickinson. (1993) Studies on the reactivity of acyl glucuronides—IV. Biochemical Pharmacology 45:5, pages 1043-1047.
Crossref
Crossref
Peter L. M. Jansen, Gerard J. Mulder, Brian Burchell & Karl Walter Bock. (1992) New developments in glucuronidation research: Report of a workshop on “Glucuronidation, its role in health and disease”. Hepatology 15:3, pages 532-544.
Crossref
Crossref
Adrienne M. Williams, Simon Worrall, John de Jersey & Ronald G. Dickinson. (1992) Studies on the reactivity of acyl glucuronides—III. Biochemical Pharmacology 43:4, pages 745-755.
Crossref
Crossref
Ronald G. Dickinson & Andrew R. King. (1991) Studies on the reactivity of acyl glucuronides—II. Biochemical Pharmacology 42:12, pages 2301-2306.
Crossref
Crossref
Andrew R. King & Ronald G. Dickinson. (1991) Studies on the reactivity of acyl glucuronides—I. Biochemical Pharmacology 42:12, pages 2289-2299.
Crossref
Crossref
RG Dickinson, RK Verbeeck, AR King, AC Restifo & SM Pond. (1991) Diflunisal and its conjugates in patients with renal failure.. British Journal of Clinical Pharmacology 31:5, pages 546-550.
Crossref
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