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Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 5
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Original Article

Age-related changes in metabolism of diethofencarb: Relationship between metabolism in rat and hepatic drug-metabolizing enzyme activities

K. Saito Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd, 1-98, 3-Chome, Kasugade-Naka, Konohana-Ku, Osaka, 544, Japan
,
H. Kaneko Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd, 1-98, 3-Chome, Kasugade-Naka, Konohana-Ku, Osaka, 544, Japan
,
K. Sato Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd, 1-98, 3-Chome, Kasugade-Naka, Konohana-Ku, Osaka, 544, Japan
,
A. Yoshitake Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd, 1-98, 3-Chome, Kasugade-Naka, Konohana-Ku, Osaka, 544, Japan
&
H. Yamada Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd, 1-98, 3-Chome, Kasugade-Naka, Konohana-Ku, Osaka, 544, Japan
Pages 575-582 | Received 21 May 1990, Accepted 18 Nov 1990, Published online: 27 Aug 2009

Citations (14)

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Y. Tomigahara, M. Onogi, K. Saito, N. Isobe, H. Kaneko & I. Nakatsuka. (2000) Metabolism of Cyanox in rat. II. Sex-related differences in oxidative dearylation and desulphuration. Xenobiotica 30:4, pages 395-406.
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Y. TOMIGAHARA*M. ONOGI, K. SAITO, H. KANEKO, I. NAKATSUKA & S. YAMANE. (1997) Metabolism of tetramethrin isomers in rat: IV. Tissues responsible for formation of reduced and hydrated metabolites. Xenobiotica 27:9, pages 961-971.
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Y. Tomigahara, M. Onogi, M. Miki, K. Yanagi, K. Shiba, H. Kaneko, I. Nakatsuka & H. Yamada. (1996) Metabolism of tetramethrin isomers in rat. III. Stereochemistry of reduced metabolites. Xenobiotica 26:2, pages 201-210.
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Y. Tomigahara, M. Onogi, K. Saito, K. Shiba, H. Kaneko, I. Nakatsuka & H. Yamada. (1995) Metabolism of Cyanox in the rat. I. Absorption, disposition, excretion and biotransformation. Xenobiotica 25:11, pages 1195-1206.
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Y. Tomigahara, K. Shiba, N. Isobe, H. Kaneko, I. Nakatsuka & H. Yamada. (1994) Identification of two new types of S-linked conjugates of Etoc in rat. Xenobiotica 24:9, pages 839-852.
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Y. Tomigahara, M. Mori, K. Shiba, N. Isobe, H. Kaneko, I. Nakatsuka & H. Yamada. (1994) Metabolism of tetramethrin isomers in rat. I. Identification of a sulphonic acid type of conjugate and reduced metabolites. Xenobiotica 24:5, pages 473-484.
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Y. Tomigahara, M. Mori, K. Shiba, N. Isobe, H. Kaneko, I. Nakatsuka & H. Yamada. (1994) Metabolism of tetramethrin isomers in rat: II. Identification and quantitation of metabolites. Xenobiotica 24:12, pages 1205-1214.
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H. Yoshino, H. Kaneko, I. Nakatsuka & H. Yamada. (1993) Metabolism of N-[4-chloro-2-fluoro-5-[(1-methyl-2-propynyl)oxy]phenyl]-3,4,5,6-tetrahydrophthalimide (S-23121) in the rat. II. Absorption, disposition, excretion and biotransformation. Xenobiotica 23:10, pages 1075-1084.
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H. Yoshino, H. Matsunaga, H. Kaneko, A. Yoshitake, I. Nakatsuka & H. Yamada. (1993) Metabolism of N-[4-chloro-2-fluoro-5-[(1-methyl-2-propynyl)oxy]phenyl]-3,4,5,6-tetrahydrophthalimide (S-23121) in the rat: I. Identification of a new, sulphonic acid type of conjugate. Xenobiotica 23:6, pages 609-619.
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Articles from other publishers (5)

Yoshitaka Tomigahara, Mihoko Onogi, Hideo Kaneko, Iwao Nakatsuka & Setsuo Yamane. (1999) Metabolism of 7-Fluoro-6-(3,4,5,6-tetrahydrophthalimido)-4- (2-propynyl)-2 H -1,4-benzoxazin-3(4 H )-one (S-53482, Flumioxazin) in the Rat:  II. Identification of Reduced Metabolites . Journal of Agricultural and Food Chemistry 47:6, pages 2429-2438.
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Yoshitaka Tomigahara, Masayoshi Matsui, Haruyuki Matsunaga, Naohiko Isobe, Hideo Kaneko, Iwao Nakatsuka, Akira Yoshitake & Setsuo Yamane. (1998) Metabolism of 7-Fluoro-6-(3,4,5,6-tetrahydrophthalimido)-4- (2-propynyl)-2 H -1,4-benzoxazin-3(4 H )-one (S-53482) in Rat. 1. Identification of a Sulfonic Acid Type Conjugate . Journal of Agricultural and Food Chemistry 47:1, pages 305-312.
Crossref
Haruyuki Matsunaga, Naohiko Isobe, Hideo Kaneko, Iwao Nakatsuka & Setsuo Yamane. (1997) Metabolism of Pentyl 2-Chloro-4-fluoro-5-(3,4,5,6-tetrahydrophthal- imido)phenoxyacetate (Flumiclorac Pentyl, S-23031) in Rats. 2. Absorption, Distribution, Biotransformation, and Excretion. Journal of Agricultural and Food Chemistry 45:2, pages 501-506.
Crossref
Hiromi Yoshino, Hideo Kaneko, Iwao Nakatsuka & Hirohiko Yamada. (1996) Metabolism of Pyriproxyfen. 3. In Vitro Metabolism in Rats and Mice . Journal of Agricultural and Food Chemistry 44:6, pages 1578-1581.
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Miranda Cornet, Karin Mertens, André Callaerts, Walter Sonck, Antoine Vercruysse & Vera Rogiers. (1994) Age- and gender-related changes in the hepatic metabolism of 2-methylpropene and relationship to epoxide metabolizing enzymes. Mechanisms of Ageing and Development 74:1-2, pages 103-115.
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