Xenobiotica

the fate of foreign compounds in biological systems

Volume 21, 1991 - Issue 5

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Original Article

Metabolism of the platelet-activating factor antagonist (±)-trans-2-(3′-methoxy-5′-methylsulphonyl-4′-propoxyphenyl)-5-(3″, 4″,5″-trimethoxyphenyl)tetrahydrofuran (L-659,989) in rhesus monkeys

K. L. Thomson Departments of Medicinal Chemical Research, Merck Sharp & Dohme Research Laboratories, Rahway, NJ, 07065-0900, USA

M. N. Chang Departments of Medicinal Chemical Research, Merck Sharp & Dohme Research Laboratories, Rahway, NJ, 07065-0900, USA

R. L. Bugianesi Departments of Medicinal Chemical Research, Merck Sharp & Dohme Research Laboratories, Rahway, NJ, 07065-0900, USA

M. M. Ponpipom Departments of Medicinal Chemical Research, Merck Sharp & Dohme Research Laboratories, Rahway, NJ, 07065-0900, USA

B. H. Arison Departments of Animal and Exploratory Drug Metabolism, Merck Sharp & Dohme Research Laboratories, Rahway, NJ, 07065-0900, USA

H. B. Hucker Departments of Animal and Exploratory Drug Metabolism, Merck Sharp & Dohme Research Laboratories, Rahway, NJ, 07065-0900, USA

B. M. Sweeney Departments of Animal and Exploratory Drug Metabolism, Merck Sharp & Dohme Research Laboratories, Rahway, NJ, 07065-0900, USA

S. D. White Departments of Animal and Exploratory Drug Metabolism, Merck Sharp & Dohme Research Laboratories, Rahway, NJ, 07065-0900, USA

J. C. Chabala Departments of Medicinal Chemical Research, Merck Sharp & Dohme Research Laboratories, Rahway, NJ, 07065-0900, USA

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Citations (4)

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Mark Whittaker. (1992) Overview: PAF Receptor Antagonists: Recent Advances. Current Opinion on Therapeutic Patents 2:5, pages 583-623.
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Articles from other publishers (3)

Mark A. Simmons. 2007. xPharm: The Comprehensive Pharmacology Reference. xPharm: The Comprehensive Pharmacology Reference 1 3 .

James B. Summers & Daniel H. Albert. 1995. 67 168 .

S.-B. Hwang. 1994. Lipid Mediators. Lipid Mediators 297 360 .

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Metabolism of the platelet-activating factor antagonist (±)-trans-2-(3′-methoxy-5′-methylsulphonyl-4′-propoxyphenyl)-5-(3″, 4″,5″-trimethoxyphenyl)tetrahydrofuran (L-659,989) in rhesus monkeys

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Metabolism of the platelet-activating factor antagonist (±)-trans-2-(3′-methoxy-5′-methylsulphonyl-4′-propoxyphenyl)-5-(3″, 4″,5″-trimethoxyphenyl)tetrahydrofuran (L-659,989) in rhesus monkeys

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