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Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 7
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Original Article

Comparison of the effects of inducers of cytochrome P450 on Mongolian gerbil and rat hepatic microsomal monooxygenase activities

J. H. Fentem Department of Physiology and Pharmacology, Medical School, Queen's Medical Centre, Clifton Boulevard, Nottingham, NG7 2UH, UK
&
J. R. Fry Department of Physiology and Pharmacology, Medical School, Queen's Medical Centre, Clifton Boulevard, Nottingham, NG7 2UH, UK
Pages 895-904 | Received 09 Sep 1990, Accepted 29 Jan 1991, Published online: 27 Aug 2009

Citations (10)

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Read on this site (3)

Rebecca C. Elton, Michael J. Garle, Jeffrey R. Fry. (2000) Glutathione depletion in a liver microsomal assay as an in vitro biomarker for reactive metabolite formation. Biomarkers 5:4, pages 285-294.
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J. H. Fentem & J. R. Fry. (1992) Metabolism of coumarin by rat, gerbil and human liver microsomes. Xenobiotica 22:3, pages 357-367.
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J. H. Fentem, A. H. Hammond & J. R. Fry. (1991) Maintenance of monooxygenase activities and detection of cytochrome P-450-mediated cytotoxicity in Mongolian gerbil hepatocyte cultures. Xenobiotica 21:10, pages 1363-1370.
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Articles from other publishers (7)

Vessela D. Kancheva, Luciano Saso, Petya V. Boranova, Abdullah Khan, Manju K. Saroj, Mukesh K. Pandey, Shashwat Malhotra, Jordan Z. Nechev, Sunil K. Sharma, Ashok K. Prasad, Maya B. Georgieva, Carleta Joseph, Anthony L. DePass, Ramesh C. Rastogi & Virinder S. Parmar. (2010) Structure–activity relationship of dihydroxy-4-methylcoumarins as powerful antioxidants: Correlation between experimental & theoretical data and synergistic effect. Biochimie 92:9, pages 1089-1100.
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B.G Lake. (1999) Coumarin Metabolism, Toxicity and Carcinogenicity: Relevance for Human Risk Assessment. Food and Chemical Toxicology 37:4, pages 423-453.
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Collins R Jones, Ronald A Lubet, John R Henneman & Raymond W Nims. (1998) Dose-response relationships for cytochrome P450 induction by phenobarbital in the cotton rat (Sigmodon hispidus). Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology 121:1-3, pages 197-203.
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Charles W QuallsJr.Jr., Ronald A. Lubet, Robert L Lochmiller, Chandikumar S Elangbam, James W. Lish & Raymond W Nims. (1998) Cytochrome P450 induction in feral Cricetid rodents: a review of field and laboratory investigations. Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology 121:1-3, pages 55-63.
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Ian Stott, Anupama Murthy, Alex Robinson, Norman W Thomas & Jeffrey R Fry. (2016) Low-dose diethyldithiocarbamate attenuates the hepatotoxicity of 1,3-Dichloro-2-propanol and selectively inhibits CYP2E1 activity in the rat. Human & Experimental Toxicology 16:5, pages 262-266.
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Julia H. Fentem, Jeffrey R. Fry & Norman W. Thomas. (1992) Species differences in the hepatotoxicity of coumarin: A comparison of rat and Mongolian gerbil. Toxicology 71:1-2, pages 129-136.
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Julia H. Fentem & Jeffrey R. Fry. (1991) Effect of cimetidine on the metabolism of coumarin by rat, gerbil and human liver microsomes. Biochemical Pharmacology 42:7, pages 1508-1510.
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