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Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 9
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Research Article

Sex differences in excretion of zenarestat in rat

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Pages 1119-1125 | Received 09 Sep 1990, Accepted 08 Feb 1991, Published online: 22 Sep 2008

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Christian Atsriku, Matthew Hoffmann, Ying Ye, Gondi Kumar & Sekhar Surapaneni. (2015) Metabolism and disposition of a potent and selective JNK inhibitor [14C]tanzisertib following oral administration to rats, dogs and humans. Xenobiotica 45:5, pages 428-441.
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Naoki Kamada, Keigo Yamada, Masaaki Odomi, Tadashi Mukai, Toru Nishibayashi, Ken-ichi Ogawara, Toshikiro Kimura & Kazutaka Higaki. (2011) Sex differences in pharmacokinetics of cilostazol in rats. Xenobiotica 41:10, pages 903-913.
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R. Webster, S. Cole, J. Gedge, S. Roffey, D. Walker & W. Wild. (2003) Pharmacokinetics and disposition of a novel NMDA glycine site antagonist (UK-240,455) in rats, dogs and man. Xenobiotica 33:5, pages 541-560.
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Y. Yamaguchi, R. Norikura, M. Nakanishi, A. Touchi, T. Yoshimori, T. Murakami, T. Baba, K. Mizojiri & T. Matsubara. (1996) Sex differences in the metabolism of (+)-S-145, a novel thromboxane A2 receptor antagonist in rat. Xenobiotica 26:6, pages 613-626.
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S. Terashita, T. Sawamoto, S. Deguchi, Y. Tokuma & T. Hata. (1995) Sex-dependent and independent renal excretion of nilvadipine metabolites in rat: evidence for a sex-dependent active secretion in kidney. Xenobiotica 25:1, pages 37-47.
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Y. Tanaka, Y. Kadoh & H. Ishikawa. (1992) Effects of hypophysectomy and testosterone treatment on the urinary excretion of zenarestat in rats. Xenobiotica 22:1, pages 51-55.
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Y. Tanaka, T. Fujiwara & Y. Esumi. (1992) Sex difference in the excretion of zenarestat in mice, rats, dogs and humans. Xenobiotica 22:8, pages 941-947.
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Rachel Rogers Worley & Jeffrey Fisher. (2015) Application of physiologically-based pharmacokinetic modeling to explore the role of kidney transporters in renal reabsorption of perfluorooctanoic acid in the rat. Toxicology and Applied Pharmacology 289:3, pages 428-441.
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Mitchell E. Taub, Eva Ludwig-Schwellinger, Naoki Ishiguro, Wataru Kishimoto, Hongbin Yu, Klaus Wagner & Donald Tweedie. (2015) Sex-, Species-, and Tissue-Specific Metabolism of Empagliflozin in Male Mouse Kidney Forms an Unstable Hemiacetal Metabolite (M466/2) That Degrades to 4-Hydroxycrotonaldehyde, a Reactive and Cytotoxic Species. Chemical Research in Toxicology 28:1, pages 103-115.
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Yoshio Tanaka & Akira Suzuki. (1994) Enzymatic Hydrolysis of Zenarestat 1- O -Acylglucuronide . Journal of Pharmacy and Pharmacology 46:3, pages 235-239.
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Chandra Prakash, Weichao Chen, Michelle Rossulek, Kim Johnson, Chenghong Zhang, Thomas O'Connell, Michael Potchoiba & Deepak Dalvie. (2008) Metabolism, Pharmacokinetics, and Excretion of a Cholesteryl Ester Transfer Protein Inhibitor, Torcetrapib, in Rats, Monkeys, and Mice: Characterization of Unusual and Novel Metabolites by High-Resolution Liquid Chromatography-Tandem Mass Spectrometry and 1 H Nuclear Magnetic Resonance . Drug Metabolism and Disposition 36:10, pages 2064-2079.
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Ivan Sabolić, Abdul R. Asif, Wolfgang E. Budach, Christoph Wanke, Andrew Bahn & Gerhard Burckhardt. (2007) Gender differences in kidney function. Pflügers Archiv - European Journal of Physiology 455:3, pages 397-429.
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Chandra Prakash, Donghui Cui, Michael J. Potchoiba & Todd Butler. (2007) Metabolism, Distribution and Excretion of a Selective N -Methyl-d-Aspartate Receptor Antagonist, Traxoprodil, in Rats and Dogs . Drug Metabolism and Disposition 35:8, pages 1350-1364.
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Carlotta E. Groves, Wendy B. Suhre, Nathan J. Cherrington & Stephen H. Wright. (2006) Sex Differences in the mRNA, Protein, and Functional Expression of Organic Anion Transporter (Oat) 1, Oat3, and Organic Cation Transporter (Oct) 2 in Rabbit Renal Proximal Tubules. Journal of Pharmacology and Experimental Therapeutics 316:2, pages 743-752.
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Yorishige Imamura & Hideaki Shimada. (2004) Strain‐ and sex‐related differences of carbonyl reductase activities in kidney microsomes and cytosol of rats. Journal of Applied Toxicology 24:6, pages 437-441.
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Marilyn E. Morris, Hwa-Jeong Lee & Lisa M. Predko. (2003) Gender Differences in the Membrane Transport of Endogenous and Exogenous Compounds. Pharmacological Reviews 55:2, pages 229-240.
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Yukio Kato, Kiyoka Kuge, Hiroyuki Kusuhara, Peter J. Meier & Yuichi Sugiyama. (2002) Gender Difference in the Urinary Excretion of Organic Anions in Rats. Journal of Pharmacology and Experimental Therapeutics 302:2, pages 483-489.
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Yasumasa GotohYukio Kato, Bruno Stieger, Peter J. Meier & Yuichi Sugiyama. (2002) Gender difference in the Oatp1-mediated tubular reabsorption of estradiol 17β- d -glucuronide in rats . American Journal of Physiology-Endocrinology and Metabolism 282:6, pages E1245-E1254.
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Naomi Kudo, Masanori Katakura, Yasunori Sato & Yoichi Kawashima. (2002) Sex hormone-regulated renal transport of perfluorooctanoic acid. Chemico-Biological Interactions 139:3, pages 301-316.
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Hiroyuki Nakajima, Hiroyasu Naba, Takeshi Nakanishi, Kiyohiko Nakai, Takanori Watanabe, Keiichi Ida & Nobuo Ohzawa. (2002) Studies on the Metabolic Fate of M17055, a Novel Diuretic (5): Pharmacokinetics and Pharmacodynamics of Unchanged Drug in Rat and Dog After Intravenous Administration of M17055. Drug Metabolism and Pharmacokinetics 17:3, pages 214-220.
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Efim B. Berkhin & Michael H. Humphreys. (2001) Regulation of renal tubular secretion of organic compounds. Kidney International 59:1, pages 17-30.
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