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Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 11
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Research Article

Absence of phenolic glucuronidation and enhanced hydroxylation of diflunisal in the homozygous Gunn rat

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Pages 1535-1546 | Received 28 Jan 1991, Accepted 12 Jul 1991, Published online: 22 Sep 2008

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Read on this site (2)

F. M. Brunelle & R. K. Verbeeck. (1996) Glucuronidation of diflunisal in liver and kidney microsomes of rat and man. Xenobiotica 26:2, pages 123-131.
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J. I. Macdonald, R. G. Dickinson, R. S. Reid, R. W. Edom, A. R. King & R. K. Verbeeck. (1991) Identification of a hydroxy metabolite of diflunisal in rat and human urine. Xenobiotica 21:11, pages 1521-1533.
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Articles from other publishers (8)

Benedetta C. Sallustio. 2008. 57 86 .
Suk K. Hong, Dianne K. Anestis, Patrick I. Brown & Gary O. Rankin. (1999) Effect of glucuronidation substrates/inhibitors on N-(3,5-dichlorophenyl)succinimidenephrotoxicity in Fischer 344 rats. Toxicology 132:1, pages 43-55.
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Suk K. Hong, Dianne K. Anestis, Christopher Skaggs, Patrick I. Brown & Gary O. Rankin. (1999) The Role of Glucuronidation inN-(3,5-Dichlorophenyl)succinimide (NDPS) Nephrotoxicity: Nephrotoxic Potential of NDPS and NDPS Metabolites in Gunn, Wistar, and Fischer 344 Rats. Toxicology and Applied Pharmacology 154:2, pages 170-180.
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Gary O Rankin, Suk K Hong, Monica A Valentovic, Kelly W Beers, Dianne K Anestis, Derek W. Nicoll, John G Ball & Patrick I Brown. (1997) Effects of sodium sulfate on acute N-(3,5-dichlorophenyl)succinimide (NDPS) nephrotoxicity in the Fischer 344 rat. Toxicology 123:1-2, pages 1-13.
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Françoise M. Brunelle & Roger K. Verbeeck. (1997) Conjugation-deconjugation cycling of diflunisal via β-glucuronidase catalyzed hydrolysis of its acyl glucuronide in the rat. Life Sciences 60:22, pages 2013-2021.
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R.G Dickinson, A.R King, M.A Kelly, I.A Kaltashov & C Fenselau. (1994) Excretion of 3-hydroxy-diflunisal as a monosulphate conjugate—identification using ESI-MS. Journal of Pharmaceutical and Biomedical Analysis 12:9, pages 1075-1078.
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N. Grubb, J. Caldwell & M. Strolin-Benedetti. (1993) Excretion balance and urinary metabolites of the S-enantiomer of indobufen in rats and mice. Biochemical Pharmacology 46:8, pages 1507-1510.
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Andrew R. King & Ronald G. Dickinson. (1991) Studies on the reactivity of acyl glucuronides—I. Biochemical Pharmacology 42:12, pages 2289-2299.
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