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Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 12
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Research Article

Regulation of rat hepatic cytochrome P450IIE1 in primary monolayer hepatocyte culture

C. M. Hunt Department of Medicine, Duke University Medical Center, Durham, NC, 27710, USA
,
P. S. Guzelian Department of Medicine, Medical College of Virginia, Richmond, VA, 23298, USA
,
D. T. Molowa Merck, Sharp and Dohme Research Laboratories, Rahway, NJ, 07065, USA
&
S. A. Wright Eli Lilly & Company, Indianapolis, IN, 46285, USA
Pages 1621-1631 | Received 29 May 1990, Accepted 09 Oct 1990, Published online: 22 Sep 2008

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Ying-Hue Lee, Masahiko Yano, Su-Yan Liu, Eiji Matsunaga, Peter F. Johnson & Frank J. Gonzalez. (1994) A Novel cis-Acting Element Controlling the Rat CYP2D5 Gene and Requiring Cooperativity Between C/EBPβ and an Sp1 Factor. Molecular and Cellular Biology 14:2, pages 1383-1394.
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Articles from other publishers (12)

M. Lindell, M. O. Karlsson, H. Lennernäs, L. Påhlman & M. A. Lang. (2003) Variable expression of CYP and Pgp genes in the human small intestine. European Journal of Clinical Investigation 33:6, pages 493-499.
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C Eeckhoutte, A Giuliano Albo, M Carletti, A Rossetto Giaccherino, P Galtier, C Nebbia & M Dacasto. (2002) Time-dependent variations of drug-metabolising enzyme activities (DMEs) in primary cultures of rabbit hepatocytes. Toxicology in Vitro 16:4, pages 375-382.
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Elena Doran, Frances W. Whittington, Jeffrey D. Wood & John D. McGivan. (2002) Cytochrome P450IIE1 (CYP2E1) is induced by skatole and this induction is blocked by androstenone in isolated pig hepatocytes. Chemico-Biological Interactions 140:1, pages 81-92.
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David A. Morgott. 2003. Patty's Toxicology. Patty's Toxicology.
Raymond F. Novak & Kimberley J. Woodcroft. (2000) The alcohol-inducible form of cytochrome P450 (CYP2E1): Role in toxicology and regulation of expression. Archives of Pharmacal Research 23:4, pages 267-282.
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U Zanelli, V Longo, A Paolicchi & P.G Gervasi. (2000) Stabilization of cytochrome P4502E1 protein by ethanol in primary hamster hepatocyte cultures. Toxicology in Vitro 14:1, pages 69-77.
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Julio C. Davila & Dale L. Morris. (1999) Analysis of cytochrome P450 and phase II conjugating enzyme expression in adult male rat hepatocytes. In Vitro Cellular & Developmental Biology - Animal 35:3, pages 120-130.
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Kimberley J. Woodcroft & Raymond F. Novak. (1997) Insulin effects on CYP2E1, 2B, 3A, and 4A expression in primary cultured rat hepatocytes. Chemico-Biological Interactions 107:1-2, pages 75-91.
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Edward L. LeCluyse, Peter L. Bullock & Andrew Parkinson. (1996) Strategies for restoration and maintenance of normal hepatic structure and function in long-term cultures of rat hepatocytes. Advanced Drug Delivery Reviews 22:1-2, pages 133-186.
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Joanne Zurlo & Linda M. Arterburn. (1996) Characterization of a primary hepatocyte culture system for toxicological studies. In Vitro Cellular & Developmental Biology - Animal 32:4, pages 211-220.
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P. Skett. (1994) Problems in using isolated and cultured hepatocytes for xenobiotic metabolism/metabolism-based toxicity testing—Solutions?. Toxicology in Vitro 8:3, pages 491-504.
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V. Rogiers & A. Vercruysse. (1993) Rat hepatocyte cultures and co-cultures in biotransformation studies of xenobiotics. Toxicology 82:1-3, pages 193-208.
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