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Xenobiotica
the fate of foreign compounds in biological systems
Volume 22, 1992 - Issue 9-10
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Research Article

Polymorphism in stereoselective hydroxylations of mephenytoin and hexobarbital by Japanese liver samples in relation to cytochrome P-450 human-2 (IIC9)

R. Kato Department of Pharmacology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160, Japan
,
Y. Yamazoe Department of Pharmacology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160, Japan
&
T. Yasumori Department of Pharmacology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160, Japan
Pages 1083-1092 | Received 05 Oct 1990, Accepted 06 Apr 1992, Published online: 22 Sep 2008

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O. PELKONEN, J. MÄEENPÄEÄ, P. TAAVITSAINEN, A. RAUTIO & H. RAUNIO. (1998) Inhibition and induction of human cytochrome P450 (CYP) enzymes. Xenobiotica 28:12, pages 1203-1253.
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Articles from other publishers (4)

Taisuke Uchida, Takashi Watanabe, Ewoud J Van Hoogdalem & Saburo Higuchi. (1996) In-vitro Metabolism of YM17E, an Inhibitor of Acyl Coenzyme A: Cholesterol Acyltransferase, by Liver Microsomes in Man. Journal of Pharmacy and Pharmacology 48:10, pages 1049-1056.
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Kunio Itoh, Yumi Nishiya, Wataru Takasaki, Mayuko Adachi & Yorihisa Tanaka. (2006) Enantioselective 2-hydroxylation of RS-8359, a selective and reversible MAO-A inhibitor, by cytochrome P450 in mouse and rat liver microsomes. Chirality 18:8, pages 592-598.
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Hakam F. Hadidi, Yacoub M. Irshaid, Raymond L. Woosley, Jeffrey R. Idle & David A. Flockhart. (1995) S-Mephenytoin hydroxylation phenotypes in a Jordanian population*. Clinical Pharmacology & Therapeutics 58:5, pages 542-547.
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Richard J. Weaver, Maurice Dickins & M.Danny Burke. (1995) Hydroxylation of the antimalarial drug 58C80 by CYP2C9 in human liver microsomes: Comparison with mephenytoin and tolbutamide hydroxylations. Biochemical Pharmacology 49:7, pages 997-1004.
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