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Xenobiotica
the fate of foreign compounds in biological systems
Volume 22, 1992 - Issue 1
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Research Article

Metabolism by rat liver cytosol of illudin S, a toxic substance of Lampteromyces japonicus. II. Characterization of illudin S-metabolizing enzyme

K. Tanaka National Research Institute of Police Science, 6, Sanban-cho, Chiyoda-ku, Tokyo 102, Japan
,
T. Inoue National Research Institute of Police Science, 6, Sanban-cho, Chiyoda-ku, Tokyo 102, Japan
,
S. Kadota Research Institute for Wakan-Yaku (Oriental Medicines), Toyama Medical and Pharmaceutical University, 2630, Sugitani, Toyama, 930-01, Japan
&
T. Kikuchi Research Institute for Wakan-Yaku (Oriental Medicines), Toyama Medical and Pharmaceutical University, 2630, Sugitani, Toyama, 930-01, Japan
Pages 33-39 | Received 14 Mar 1991, Published online: 22 Sep 2008

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N. Tani, M. Yabuki, S. Komuro & H. Kanamaru. (2005) Characterization of the enzymes involved in the in vitro metabolism of amrubicin hydrochloride. Xenobiotica 35:12, pages 1121-1133.
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K. Tanaka, T. Inoue, Y. Tezuka & T. Kikuchi. (1996) Metabolism of illudin S, a toxic substance of Lampteromyces japonicus: urinary excretion of mercapturic acids in rat. Xenobiotica 26:3, pages 347-354.
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K. Tanaka, T. Inoue, M. Kanai & T. Kikuchi. (1994) Metabolism of illudin S, a toxic substance of Lampteromyces japonicus. IV. Urinary excretion of an illudin S metabolite in rat. Xenobiotica 24:12, pages 1237-1243.
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Articles from other publishers (10)

Philipp Le, Matthew B. Nodwell, Jürgen Eirich & Stephan A. Sieber. (2019) A Chemical Proteomic Analysis of Illudin‐Interacting Proteins. Chemistry – A European Journal 25:54, pages 12644-12651.
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Marina Tanasova & Shana J. Sturla. (2012) Chemistry and Biology of Acylfulvenes: Sesquiterpene-Derived Antitumor Agents. Chemical Reviews 112:6, pages 3578-3610.
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Sebastian Knauer, Bernhard Biersack, Miroslava Zoldakova, Katharina Effenberger, Wolfgang Milius & Rainer Schobert. (2009) Melanoma-specific ferrocene esters of the fungal cytotoxin illudin M. Anti-Cancer Drugs 20:8, pages 676-681.
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Xiaodan Liu & Shana J. Sturla. (2009) Profiling patterns of glutathione reductase inhibition by the natural product illudin S and its acylfulvene analogues. Molecular BioSystems 5:9, pages 1013.
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Ryan A. Dick, Xiang Yu & Thomas W. Kensler. (2004) NADPH Alkenal/One Oxidoreductase Activity Determines Sensitivity of Cancer Cells to the Chemotherapeutic Alkylating Agent Irofulven. Clinical Cancer Research 10:4, pages 1492-1499.
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Trevor C McMorris. (1999) Discovery and development of sesquiterpenoid derived hydroxymethylacylfulvene: a new anticancer drug. Bioorganic & Medicinal Chemistry 7:5, pages 881-886.
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Trevor C. McMorris, Anissa N. Elayadi, Jian Yu & Michael J. Kelner. (1999) Metabolism of antitumor acylfulvene by rat liver cytosol. Biochemical Pharmacology 57:1, pages 83-88.
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Trevor C. McMorris, Jian Yu, Leita A. Estes & Michael J. Kelner. (1997) Reaction of antitumor hydroxymethylacylfulvene (HMAF) with thiols. Tetrahedron 53:43, pages 14579-14590.
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T. C. McMorris, M. J. Kelner, W. Wang, M. A. Diaz, L. A. Estes & R. Taetle. (1996) Acylfulvenes, a new class of potent antitumor agents. Experientia 52:1, pages 75-80.
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Michael J. Kelner, Trevor C. McMorris, Leita Estes, Mary Rutherford, Mark Montoya, Jill Goldstein, Kyra Samson, Robin Starr & Raymond Taetle. (1994) Characterization of illudin S sensitivity in DNA repair-deficient chinese hamster cells. Biochemical Pharmacology 48:2, pages 403-409.
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