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Xenobiotica
the fate of foreign compounds in biological systems
Volume 23, 1993 - Issue 9
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Research Article

Bioavailability and disposition of ‘H-solanine in rat and hamster

K. Groen Unit of Biotransformation, Pharmaco- and Toxicokinetics, Bilthoven, The Netherlands
,
D. P. K. H. Pereboom-De Fauw Unit of Biotransformation, Pharmaco- and Toxicokinetics, Bilthoven, The Netherlands
,
P. Besamusca Unit of Biotransformation, Pharmaco- and Toxicokinetics, Bilthoven, The Netherlands
,
P. K. Beekhof Laboratory of Toxicology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands
,
G. J. A. Speijers Laboratory of Toxicology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands
&
H. J. G. M. Derks Unit of Biotransformation, Pharmaco- and Toxicokinetics, Bilthoven, The Netherlands
Pages 995-1005 | Received 23 Mar 1993, Accepted 13 May 1993, Published online: 22 Sep 2008

Citations (12)

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Mendel Friedman, GaryM. McDonald & MaryAnn Filadelfi-Keszi. (1997) Potato Glycoalkaloids: Chemistry, Analysis, Safety, and Plant Physiology. Critical Reviews in Plant Sciences 16:1, pages 55-132.
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Articles from other publishers (11)

Matthias Kasimir, Alessa Wolbeck, Matthias Behrens & Hans-Ulrich Humpf. (2023) Intestinal Metabolism of Selected Steroidal Glycoalkaloids in the Pig Cecum Model. ACS Omega 8:20, pages 18266-18274.
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T. O. Ostreikova, O. V. Kalinkina, N. G. Bogomolov & I. V. Chernykh. (2022) Glycoalkaloids of Plants in the Family Solanaceae (Nightshade) as Potential Drugs. Pharmaceutical Chemistry Journal 56:7, pages 948-957.
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Dieter Schrenk, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Jesús del Mazo, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Christiane Vleminckx, Heather Wallace, Leon Brimer, Bruce Cottrill, Birgit Dusemund, Patrick Mulder, Günter Vollmer, Marco Binaglia, Luisa Ramos Bordajandi, Francesca Riolo, Ruth Roldán‐Torres & Bettina Grasl‐Kraupp. (2020) Risk assessment of glycoalkaloids in feed and food, in particular in potatoes and potato‐derived products. EFSA Journal 18:8.
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Ayşe Karaboğa Arslan & Mükerrem Yerer. (2018) α-Chaconine and α-Solanine Inhibit RL95-2 Endometrium Cancer Cell Proliferation by Reducing Expression of Akt (Ser473) and ERα (Ser167). Nutrients 10:6, pages 672.
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Søren Langkilde, Malene Schrøder, Thomas Frank, Louise V.T. Shepherd, Sean Conner, Howard V. Davies, Otto Meyer, Jürgen Danier, Michael Rychlik, William R. Belknap, Kent F. McCue, Karl-Heinz Engel, Derek Stewart, Ib Knudsen & Morten Poulsen. (2012) Compositional and toxicological analysis of a GM potato line with reduced α-solanine content – A 90-day feeding study in the Syrian Golden hamster. Regulatory Toxicology and Pharmacology 64:1, pages 177-185.
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Irina I. Koleva, Teris A. van Beek, Ans E. M. F. Soffers, Birgit Dusemund & Ivonne M. C. M. Rietjens. (2011) Alkaloids in the human food chain – Natural occurrence and possible adverse effects. Molecular Nutrition & Food Research 56:1, pages 30-52.
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Søren Langkilde, Tafadzwa Mandimika, Malene Schrøder, Otto Meyer, Wout Slob, Ad Peijnenburg & Morten Poulsen. (2009) A 28-day repeat dose toxicity study of steroidal glycoalkaloids, α-solanine and α-chaconine in the Syrian Golden hamster. Food and Chemical Toxicology 47:6, pages 1099-1108.
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Søren Langkilde, Malene Schrøder, Derek Stewart, Otto Meyer, Sean Conner, Howard Davies & Morten Poulsen. (2008) Acute Toxicity of High Doses of the Glycoalkaloids, α-Solanine and α-Chaconine, in the Syrian Golden Hamster. Journal of Agricultural and Food Chemistry 56:18, pages 8753-8760.
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Mendel Friedman. (2006) Potato Glycoalkaloids and Metabolites:  Roles in the Plant and in the Diet. Journal of Agricultural and Food Chemistry 54:23, pages 8655-8681.
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B.J. Phillips, J.A. Hughes, J.C. Phillips, D.G. Walters, D. Anderson & C.S.M. Tahourdin. (1996) A study of the toxic hazard that might be associated with the consumption of green potato tops. Food and Chemical Toxicology 34:5, pages 439-448.
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Darcy C. Abell & Peter Sporns. (1996) Rapid Quantitation of Potato Glycoalkaloids by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry. Journal of Agricultural and Food Chemistry 44:8, pages 2292-2296.
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