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Xenobiotica
the fate of foreign compounds in biological systems
Volume 23, 1993 - Issue 5
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Research Article

Metabolism of thiodiglycol (2,2′-thiobis-ethanol): isolation and identification of urinary metabolites following intraperitoneal administration to rat

R. M. Black Chemical and Biological Defence Establishment, Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK
,
K. Brewster Chemical and Biological Defence Establishment, Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK
,
R. J. Clarke Chemical and Biological Defence Establishment, Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK
,
J. L. Hambrook Chemical and Biological Defence Establishment, Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK
,
J. M. Harrison Chemical and Biological Defence Establishment, Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK
&
D. J. Howells Chemical and Biological Defence Establishment, Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK
Pages 473-481 | Received 26 Nov 1992, Accepted 23 Feb 1993, Published online: 22 Sep 2008

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R. M. Black & R. W. Read. (1995) Biological fate of sulphur mustard, 1,1′-thiobis(2-chloroethane): identification of β-lyase metabolites and hydrolysis products in human urine. Xenobiotica 25:2, pages 167-173.
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Articles from other publishers (19)

Christine Ann Arenal, Bradley E. Sample, Glenn J. Leach & Gunda Reddy. 2015. Wildlife Toxicity Assessments for Chemicals of Military Concern. Wildlife Toxicity Assessments for Chemicals of Military Concern 651 668 .
Richard A. Angerhofer, Mark W. Michie, Glenn J. Leach, Mark S. Johnson & Gunda Reddy. (2014) Oral Toxicity Evaluation of Thiodiglycol in Sprague-Dawley Rats. International Journal of Toxicology 33:5, pages 393-402.
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. (2012) Scientific Opinion on Flavouring Group Evaluation 08, Revision 5 (FGE.08Rev5): Aliphatic and alicyclic mono‐, di‐, tri‐, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30. EFSA Journal 10:7.
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. (2012) Scientific Opinion on Flavouring Group Evaluation 08, Revision 4 (FGE.08Rev4): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30. EFSA Journal 10:2, pages 2455.
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N. G. Medvedeva, Yu. M. Polyak, T. B. Zaytseva & G. A. Zharikov. (2012) Destruction of mustard gas hydrolysis products by marine and soil bacteria. Biology Bulletin 39:1, pages 77-84.
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A.A. Brimfield. 2012. Toxicology and Human Environments. Toxicology and Human Environments 209 230 .
. (2011) Scientific Opinion on Flavouring Group Evaluation 8, Revision 3 (FGE.08Rev3): Aliphatic and alicyclic mono‐, di‐, tri‐, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30. EFSA Journal 9:5.
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. (2010) Flavouring Group Evaluation 08 Rev2 (FGE.08 Rev2): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30. EFSA Journal 8:11, pages 1408.
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. (2010) Flavouring Group Evaluation 8, Revision 1 (FGE.08Rev1): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30. EFSA Journal 8:7, pages 1021.
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Nadezda Medvedeva, Yulia Polyak, Harri Kankaanpää & Tatyana Zaytseva. (2009) Microbial responses to mustard gas dumped in the Baltic Sea. Marine Environmental Research 68:2, pages 71-81.
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. (2009) Application (Reference EFSA‐GMO‐NL‐2008‐51) for the placing on the market of glyphosate tolerant genetically modified cotton GHB614, for food and feed uses, import and processing under Regulation (EC) No 1829/2003 from Bayer CropScience. EFSA Journal 7:3.
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Mark J. Novak & Alan A. Brimfield. (2006) NMR Analysis of Thiodiglycol Oxidation by Mammalian Alcohol Dehydrogenases. Current Protocols in Toxicology 29:1.
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A.A. Brimfield, Mark J. Novak & Ernest Hodgson. (2006) Thiodiglycol, the hydrolysis product of sulfur mustard: Analysis of in vitro biotransformation by mammalian alcohol dehydrogenases using nuclear magnetic resonance. Toxicology and Applied Pharmacology 213:3, pages 207-215.
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Gunda Reddy, Michael A. Major & Glenn J. Leach. (2016) Toxicity Assessment of Thiodiglycol. International Journal of Toxicology 24:6, pages 435-442.
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Om Kumar, K. Sugendran & R. Vijayaraghavan. (2001) Protective effect of various antioxidants on the toxicity of sulphur mustard administered to mice by inhalation or percutaneous routes. Chemico-Biological Interactions 134:1, pages 1-12.
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Robin M. Black, Robert W Read & Daan Noort. 2007. Encyclopedia of Analytical Chemistry. Encyclopedia of Analytical Chemistry 1 32 .
Ch.E. Kientz. (1998) Chromatography and mass spectrometry of chemical warfare agents, toxins and related compounds: state of the art and future prospects. Journal of Chromatography A 814:1-2, pages 1-23.
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Tsu-Shun Lee, William A. Weigand & William E. Bentley. (1997) Observations of metabolite formation and variable yield in thiodiglycol biodegradation process. Applied Biochemistry and Biotechnology 63-65:1, pages 743-757.
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Tsu-Shun Lee, William A. Weigand & William E. Bentley. 1997. Biotechnology for Fuels and Chemicals. Biotechnology for Fuels and Chemicals 743 757 .

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