Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 23, 1993 - Issue 11
Submit an article Journal homepage
41
Views
27
CrossRef citations to date
0
Altmetric
Research Article

Pharmacokinetics and pharmacodynamics in the critically ill patient

G. R. Park The John Farman Intensive Care Unit, Addenbrooke's NHS Trust, Hills Road, Cambridge, CB2 2QQ, UK
Pages 1195-1230 | Received 02 Feb 1993, Accepted 14 Jun 1993, Published online: 22 Sep 2008

Citations (27)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

A.S.J.P.A.M. van Miert. (2000) Trends in veterinary clinical and fundamental pharmacology: Past and future in the Netherlands. Veterinary Quarterly 22:1, pages 3-11.
Read now
Silvio Garattini. (1997) Drug Metabolism: From Experiments to Regulatory Aspects. Drug Metabolism Reviews 29:3, pages 853-886.
Read now
R MARCUS & G R PARK. (1995) Drugs: stop 'one a day'. Clinical Intensive Care 6:6, pages 286-287.
Read now

Articles from other publishers (24)

Sandrina L. von Winckelmann, Isabel Spriet & Ludo Willems. (2012) Therapeutic Drug Monitoring of Phenytoin in Critically Ill Patients. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 28:11, pages 1391-1400.
Crossref
Michel MRF Struys, Alain Kalmar & Peter De Paepe. 2006. Anaesthesia Science. Anaesthesia Science 1 25 .
M. Ruß, M. Seige & K. Werdan. 2005. Therapie innerer Krankheiten. Therapie innerer Krankheiten 280 341 .
Gustav Paumgartner & Gerhard SteinbeckM. Seige & K. Werdan. 2003. Therapie innerer Krankheiten. Therapie innerer Krankheiten 267 323 .
Andrew K Davey. (2002) Clinical Relevance of Cytokine‐Induced Changes in Drug Metabolism. Journal of Pharmacy Practice and Research 32:2, pages 147-152.
Crossref
Peter De Paepe, Frans M. Belpaire & Walter A. Buylaert. (2002) Pharmacokinetic and Pharmacodynamic Considerations When Treating Patients with Sepsis and Septic Shock. Clinical Pharmacokinetics 41:14, pages 1135-1151.
Crossref
M. Schetz & C. Verwaest. 2001. Critical Care Infectious Diseases Textbook. Critical Care Infectious Diseases Textbook 297 312 .
Ronald J. DeBellis, Brian S. Smith, Pauline A. Cawley & Gail M. Burniske. (2016) Drug Dosing in Critically Ill Patients with Renal Failure: A Pharmacokinetic Approach. Journal of Intensive Care Medicine 15:6, pages 273-313.
Crossref
Ronald J DeBellis, Brian S Smith, Pauline A Cawley & Gail M Burniske. (2000) Drug Dosing in Critically Ill Patients with Renal Failure: A Pharmacokinetic Approach. Journal of Intensive Care Medicine 15:6, pages 273-313.
Crossref
K. Werdan & U. Müller-Werdan. 2000. Klinische Kardiologie. Klinische Kardiologie 767 796 .
K. Werdan & U. Müller-Werdan. 2000. Klinische Kardiologie. Klinische Kardiologie 753 766 .
K. Werdan & U. Müller-Werdan. 2000. Klinische Kardiologie. Klinische Kardiologie 741 752 .
K. Werdan & U. Müller-Werdan. 2000. Klinische Kardiologie. Klinische Kardiologie 737 740 .
K. Werdan & U. Müller-Werdan. 2000. Klinische Kardiologie. Klinische Kardiologie 715 735 .
K. Werdan & U. Müller-Werdan. 2000. Klinische Kardiologie. Klinische Kardiologie 703 713 .
E. Miller & G. R. Park. (2002) The effect of oxygen on propofol‐induced inhibition of microsomal cytochrome P450 3A4. Anaesthesia 54:4, pages 320-322.
Crossref
M. Seige & K. Werdan. 1999. Therapie innerer Krankheiten. Therapie innerer Krankheiten 1452 1508 .
David S. McKindley, Scott Hanes & Bradley A. Boucher. (2012) Hepatic Drug Metabolism in Critical Illness. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 18:4, pages 759-778.
Crossref
Claudio Ronco & Rinaldo BellomoMiet Schetz. 1998. Critical Care Nephrology. Critical Care Nephrology 1457 1472 .
M. K. ZAMACONA, E. SUÁREZ, L. AGUILERA, J. M. RODRÍGUEZ–SASIAÍN, C. AGUIRRE & R. CALVO. (2008) Serum protein binding of propofol in critically ill patients. Acta Anaesthesiologica Scandinavica 41:10, pages 1267-1272.
Crossref
G. R. PARK & E. MILLER. (2007) What changes drug metabolism in critically ill patients‐III? Effect of pre‐existing disease on the metabolism of midazolam. Anaesthesia 51:5, pages 431-434.
Crossref
J. Stadler, W. A. Schmalix & J. Doehmer. 1996. Biological Reactive Intermediates V. Biological Reactive Intermediates V 187 193 .
K. Werdan. 1995. Therapie innerer Krankheiten. Therapie innerer Krankheiten 1320 1366 .
Dennis V. Parke. (2020) Clinical Pharmacokinetics in Drug Safety Evaluation. Alternatives to Laboratory Animals 22:3, pages 207-209.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.