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Xenobiotica
the fate of foreign compounds in biological systems
Volume 23, 1993 - Issue 12
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Research Article

Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever

G. O. Kokwaro Department of Pharmacology and Therapeutics, University of Liverpool, PO Box 147, Liverpool, L69 3BX, UK
,
I. S. F. Szwandt Department of Pharmacology and Therapeutics, University of Liverpool, PO Box 147, Liverpool, L69 3BX, UK
,
A. P. Glazier Department of Pharmacology and Therapeutics, University of Liverpool, PO Box 147, Liverpool, L69 3BX, UK
,
S. A. Ward Department of Pharmacology and Therapeutics, University of Liverpool, PO Box 147, Liverpool, L69 3BX, UK; Division of Biomedical Science, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK
&
G. Edwards Department of Pharmacology and Therapeutics, University of Liverpool, PO Box 147, Liverpool, L69 3BX, UK; Division of Biomedical Science, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK
Pages 1391-1397 | Published online: 22 Sep 2008

Citations (7)

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Read on this site (2)

Edward T. Morgan. (1997) Regulation of Cytochromes P450 During Inflammation and Infection. Drug Metabolism Reviews 29:4, pages 1129-1188.
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M. Monshouwer, R. F. Witkamp, S. M. Nijmeijer, A. Pijpers, J. H. M. Verheijden & A. S. J. P. A. M. Van Miert. (1995) Selective effects of a bacterial infection (Actinobacillus pleuropneumoniae) on the hepatic clearances of caffeine, antipyrine, paracetamol, and indocyanine green in the pig. Xenobiotica 25:5, pages 491-499.
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Articles from other publishers (5)

Ana C.A.X. De-Oliveira & Francisco J.R. Paumgartten. (2021) Malaria-induced Alterations of Drug Kinetics and Metabolism in Rodents and Humans. Current Drug Metabolism 22:2, pages 127-138.
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Bertil B. FredholmMaurice J. Arnaud. 2011. Methylxanthines. Methylxanthines 33 91 .
Neil J. Morley. (2009) Environmental risk and toxicology of human and veterinary waste pharmaceutical exposure to wild aquatic host–parasite relationships. Environmental Toxicology and Pharmacology 27:2, pages 161-175.
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K. Uhl, J. M. Grace, D. A. Kocisko, B. T. Jennings, A. L. Mitchell & T. G. Brewer. (1999) Effects ofPlasmodium berghei infection on cytochromes P-450 2E1 and 3A2. European Journal of Drug Metabolism and Pharmacokinetics 24:2, pages 169-176.
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Arif R. Sarwari & Philip A. Mackowiak. (1996) THE PHARMACOLOGIC CONSEQUENCES OF FEVER. Infectious Disease Clinics of North America 10:1, pages 21-32.
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