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Xenobiotica
the fate of foreign compounds in biological systems
Volume 23, 1993 - Issue 7
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Original Article

Metabolic fate of a new dihydropyridine calcium antagonist, CD-349, in rat and dog

N. Ogawa Research Center, Taisho Pharmaceutical Co., Ltd., 1-403, Yoshino-Cho, Ohmiya, Saitama, 330, Japan
,
K. Mizuno Research Center, Taisho Pharmaceutical Co., Ltd., 1-403, Yoshino-Cho, Ohmiya, Saitama, 330, Japan
,
K. Fukushima Research Center, Taisho Pharmaceutical Co., Ltd., 1-403, Yoshino-Cho, Ohmiya, Saitama, 330, Japan
,
T. Suwa Research Center, Taisho Pharmaceutical Co., Ltd., 1-403, Yoshino-Cho, Ohmiya, Saitama, 330, Japan
&
T. Satoh Laboratory of Biochemical Pharmacology and Biotoxicology, Faculty of Pharmaceutical Sciences, Chiba University, 1-33, Yayoi-Cho, Chiba, 260, Japan
Pages 747-759 | Received 21 Dec 1992, Accepted 06 May 1993, Published online: 23 Apr 2010

Citations (4)

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H. Nakabeppu, M. Asada, T. Oda, Y. Shinozaki & T. Yajima. (1996) Plasma and urinary metabolites of efonidipine hydrochloride in man. Xenobiotica 26:2, pages 229-239.
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N. Ogawa, T. Hirose, K. Fukushima, T. Suwa & T. Satoh. (1995) Metabolism of a nitrate ester, dihydropyridine derivative in rabbit hepatic microsomes and cytosol. Xenobiotica 25:3, pages 283-290.
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Articles from other publishers (2)

Naoyoshi Ogawa, Takuya Hirose, Kiyomi Fukushima, Toshio Suwa & Tetsuo Satoh. (1995) GSH-independent denitration of the nitrate ester of a dihydropyridine derivative in rabbit hepatic cytosol. Biochemical Pharmacology 49:2, pages 141-146.
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Z Hernández-Gallegos, PA Lehmann F, E Hong, F Posadas & E Hernández-Gallegos. (1995) Novel halogenated 1,4-dihydropyridines: Synthesis, bioassay, microsomal oxidation and structure-activity relationships. European Journal of Medicinal Chemistry 30:5, pages 355-364.
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