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Xenobiotica
the fate of foreign compounds in biological systems
Volume 24, 1994 - Issue 1
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Original Article

Inhibition of rat liver cytosolic glutathione S-transferase by silybin

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Pages 17-24 | Received 15 Sep 1993, Published online: 27 Aug 2009

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Read on this site (4)

Barbora Szotáková, Hana Bártíková, Jitka Hlaváčová, Iva Boušová & Lenka Skálová. (2013) Inhibitory effect of anthocyanidins on hepatic glutathione S-transferase, UDP-glucuronosyltransferase and carbonyl reductase activities in rat and human. Xenobiotica 43:8, pages 679-685.
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Iva Boušová, Jan Hájek, Jaroslav Dršata & Lenka Skálová. (2012) Naturally occurring flavonoids as inhibitors of purified cytosolic glutathione S-transferase. Xenobiotica 42:9, pages 872-879.
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Petra Jančová, Michal Šiller, Eva Anzenbacherová, Vladimír Křen, Pavel Anzenbacher & Vilím Šimánek. (2011) Evidence for differences in regioselective and stereoselective glucuronidation of silybin diastereomers from milk thistle (Silybum marianum) by human UDP-glucuronosyltransferases. Xenobiotica 41:9, pages 743-751.
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Articles from other publishers (16)

Tomas Koltai & Larry Fliegel. (2022) Role of Silymarin in Cancer Treatment: Facts, Hypotheses, and Questions. Journal of Evidence-Based Integrative Medicine 27, pages 2515690X2110688.
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K. Jena, Ruchi Kumari, J.P. Pandey, P.K. Kar, J. Akhtar, A.K. Singh, V.P. Gupta & A.K. Sinha. (2021) Biochemical characterization of sericin isolated from cocoons of tropical tasar silkworm Antheraea mylitta raised on three different host plants for its prospective utilization. Journal of Asia-Pacific Entomology 24:3, pages 903-911.
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Hanna Piotrowska-Kempisty, Michał Nowicki, Jadwiga Jodynis-Liebert, Monika Kurpik, Małgorzata Ewertowska, Teresa Adamska, Jan Oszmiański & Małgorzata Kujawska. (2020) Assessment of Hepatoprotective Effect of Chokeberry Juice in Rats Treated Chronically with Carbon Tetrachloride. Molecules 25:6, pages 1268.
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K. Jena, J.P. Pandey, Ruchi Kumari, A.K. Sinha, V.P. Gupta & G.P. Singh. (2018) Free radical scavenging potential of sericin obtained from various ecoraces of tasar cocoons and its cosmeceuticals implication. International Journal of Biological Macromolecules 120, pages 255-262.
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K. Jena, J.P. Pandey, Ruchi Kumari, A.K. Sinha, V.P. Gupta & G.P. Singh. (2018) Tasar silk fiber waste sericin: New source for anti-elastase, anti-tyrosinase and anti-oxidant compounds. International Journal of Biological Macromolecules 114, pages 1102-1108.
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. 2013. Principles and Practice of Phytotherapy. Principles and Practice of Phytotherapy 353 961 .
Kiruthiga Perumal Vijayaraman, Shanmuganathan Muruganantham, Manickavalli Subramanian, Karutha Pandian Shunmugiah & Pandima Devi Kasi. (2012) Silymarin attenuates benzo(a)pyrene induced toxicity by mitigating ROS production, DNA damage and calcium mediated apoptosis in peripheral blood mononuclear cells (PBMC). Ecotoxicology and Environmental Safety 86, pages 79-85.
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M.N. Hamsar, S. Ismail, M.N. Mordi, S. Ramanathan & S.M. Mansor. (2011) Antioxidant activity and the effect of different parts of areca catechu extracts on Glutathione-S-Transferase activity in vitro. Free Radicals and Antioxidants 1:1, pages 28-33.
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Juzaili Azizi, Sabariah Ismail, Mohd Nizam Mordi, Surash Ramanathan, Mohd Ikram Mohd Said & Sharif Mahsufi Mansor. (2010) In Vitro and in Vivo Effects of Three Different Mitragyna speciosa Korth Leaf Extracts on Phase II Drug Metabolizing Enzymes—Glutathione Transferases (GSTs). Molecules 15:1, pages 432-441.
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Julie M. Bares, Jose Berger, James E. Nelson, Donald J. Messner, Sandra Schildt, Leanna J. Standish & Kris V. Kowdley. (2008) Silybin Treatment is Associated With Reduction in Serum Ferritin in Patients With Chronic Hepatitis C. Journal of Clinical Gastroenterology 42:8, pages 937-944.
Crossref
Erwin Kuntz. 2006. Hepatology Principles and Practice. Hepatology Principles and Practice 843 891 .
Vanesa D'Andrea, Leonardo M. Pérez & Enrique J. Sánchez Pozzi. (2005) Inhibition of rat liver UDP-glucuronosyltransferase by silymarin and the metabolite silibinin-glucuronide. Life Sciences 77:6, pages 683-692.
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Maxwell Afari Gyamfi, Ikuko Ichiba Ohtani, Etsuki Shinno & Yoko Aniya. (2004) Inhibition of glutathione S-transferases by thonningianin A, isolated from the African medicinal herb, Thonningia sanguinea, in vitro. Food and Chemical Toxicology 42:9, pages 1401-1408.
Crossref
Sharon A Center. (2004) Metabolic, antioxidant, nutraceutical, probiotic, and herbal therapies relating to the management of hepatobiliary disorders. Veterinary Clinics of North America: Small Animal Practice 34:1, pages 67-172.
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Joel Edwards, Linda La Grange, Mu Wang & Edward Reyes. (2000) Fetoprotectivity of the flavanolignan compound siliphos against ethanol-induced toxicity. Phytotherapy Research 14:7, pages 517-521.
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Bijoy Kundu, Sanjay K. Khare, Vishnu Ji Ram, Atul Goel, Berend Olivier, Willem Soudijn, Ineke van Wijngaarden, Jacob Szmuszkovicz & Q. May WangVishnu Ji Ram & Atul Goel. 1999. Progress in Drug Research. Progress in Drug Research 53 101 .

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