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Xenobiotica
the fate of foreign compounds in biological systems
Volume 24, 1994 - Issue 1
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Original Article

Comparative metabolism of SC-42867 and SC-51089, two PGE2 antagonists, in rat and human hepatocyte cultures

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Pages 25-36 | Received 10 Jul 1993, Published online: 27 Aug 2009

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Frank J. Belas & Ian A. Blair. (2001) MASS SPECTROMETRY IN PHARMACEUTICAL ANALYSIS*. Journal of Liposome Research 11:4, pages 309-342.
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Articles from other publishers (16)

Albert P. Li. 2018. Drug-Induced Liver Toxicity. Drug-Induced Liver Toxicity 179 197 .
Albert P. Li. (2015) Evaluation of Adverse Drug Properties with Cryopreserved Human Hepatocytes and the Integrated Discrete Multiple Organ Co-culture (IdMOC TM ) System . Toxicological Research 31:2, pages 137-149.
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Donald J. AbrahamAdrian Hall, Simon Peace & Martin E. Swarbrick. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery 791 944 .
Albert P. Li. 2010. Hepatocytes. Hepatocytes 281 294 .
Albert P. Li & Chuang Lu. 2009. Enzyme Inhibition in Drug Discovery and Development. Enzyme Inhibition in Drug Discovery and Development 423 441 .
Albert P. Li, Chris Bode & Yumiko Sakai. (2004) A novel in vitro system, the integrated discrete multiple organ cell culture (IdMOC) system, for the evaluation of human drug toxicity: comparative cytotoxicity of tamoxifen towards normal human cells from five major organs and MCF-7 adenocarcinoma breast cancer cells. Chemico-Biological Interactions 150:1, pages 129-136.
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Albert Li. 2001. Handbook of Drug Screening. Handbook of Drug Screening.
E.Ann Hallinan, Timothy J. Hagen, Sofya Tsymbalov, Awilda Stapelfeld & Michael A. Savage. (2001) 2,4-Disubstituted oxazoles and thiazoles as latent pharmacophores for diacylhydrazine of SC-51089, a potent PGE2 antagonist. Bioorganic & Medicinal Chemistry 9:1, pages 1-6.
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Albert P. Li. 2000. The Hepatocyte Review. The Hepatocyte Review 391 410 .
Albert P Li, Chuang Lu, Julie A Brent, Chuong Pham, Andrew Fackett, Charles E Ruegg & Paul M Silber. (1999) Cryopreserved human hepatocytes: characterization of drug-metabolizing activities and applications in higher throughput screening assays for hepatotoxicity, metabolic stability, and drug–drug interaction potential. Chemico-Biological Interactions 121:1, pages 17-35.
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Albert P. Li. (1999) Overview: hepatocytes and cryopreservation—a personal historical perspective. Chemico-Biological Interactions 121:1, pages 1-5.
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Noriko Masubuchi, Albert P Li & Osamu Okazaki. (1998) An evaluation of the cytochrome P450 induction potential of pantoprazole in primary human hepatocytes. Chemico-Biological Interactions 114:1-2, pages 1-13.
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ANDRÉ GUILLOUZO. 1997. In Vitro Methods in Pharmaceutical Research. In Vitro Methods in Pharmaceutical Research 411 431 .
Kwang-Sup Kil, Young-Na Yum, Seung-Hoon Seo & Kyung-Tae Lee. (1996) Antitumor activities of hypericin as a protein tyrosine kinase blocker. Archives of Pharmacal Research 19:6, pages 490-496.
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Kyung Tae Lee. (1995) In vitro covalent binding of SC-42867, PGE2 antagonist, to rat liver microsomal proteins. Archives of Pharmacal Research 18:6, pages 381-384.
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Jill C. Merrill, Dale J. Beck, Don A. Kaminski & A.P. Li. (1995) Polybrominated biphenyl induction of cytochrome P450 mixed function oxidase activity in primary rat and human hepatocytes. Toxicology 99:3, pages 147-152.
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