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Xenobiotica
the fate of foreign compounds in biological systems
Volume 24, 1994 - Issue 3
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Original Article

Effect of E-5110, a novel non-steroidal anti-flammatory drug, on trimethadione metabolism as an indicator of hepatic drug-oxidizing capacity in beagle dog

Z. Daling Eisai Research Laboratories, Eisai, Co., Ltd, Ibaraki-ken, 305, Japan
,
E. Tanaka Institute of Community Medicine, University of Tsukuba, Ibaraki-ken, 305, Japan
,
T. Nakamura Eisai Research Laboratories, Eisai, Co., Ltd, Ibaraki-ken, 305, Japan
&
T. Horie Eisai Research Laboratories, Eisai, Co., Ltd, Ibaraki-ken, 305, Japan
Pages 215-220 | Received 05 Aug 1993, Published online: 27 Aug 2009

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E. Tanaka, A. Osada, A. Ishikawa, T. Nakamura, Y. Momose, T. Mikami, K. Fukao & T. Horie. (1995) Influence of partial hepatectomy in dogs on trimethadione metabolism and microsomal monooxygenases. Xenobiotica 25:12, pages 1301-1310.
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E. Tanaka, Z. Daling, K. Abe, T. Nakamura & T. Horie. (1994) Dual effects of a novel thienodiazepine platelet-activating factor antagonist, on drug-oxidizing enzymes in beagle dog. Xenobiotica 24:4, pages 293-300.
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Articles from other publishers (3)

David E. Amacher, Shelli J. Schomaker, Sherri E. Boldt & Michael Mirsky. (2006) The relationship among microsomal enzyme induction, liver weight, and histological change in cynomolgus monkey toxicology studies. Food and Chemical Toxicology 44:4, pages 528-537.
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D.E Amacher, S.J Schomaker & J.E Burkhardt. (2001) The relationship among microsomal enzyme induction, liver weight and histological change in beagle dog toxicology studies. Food and Chemical Toxicology 39:8, pages 817-825.
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Einosuke Tanaka, Tomoyoshi Taniguchi, Yoshio Sawa, Shigeru Ohmori, Mitsukazu Kitada & Tohoru Horie. (1998) Trimethadione metabolism and microsomal monooxygenases in untreated and phenobarbital-treated rhesus monkeys. Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology 120:2, pages 317-320.
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