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Xenobiotica
the fate of foreign compounds in biological systems
Volume 24, 1994 - Issue 7
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Original Article

Effect of adjuvant-induced arthritis on hepatic drug metabolism in rats

A. Toda Faculty of Pharmaceutical Science, Fukuoka University, Nanakuma, Johnan-ku, Fukuoka, 814-01, Japan
,
N. Ishii Faculty of Pharmaceutical Science, Fukuoka University, Nanakuma, Johnan-ku, Fukuoka, 814-01, Japan
,
T. Kihara Faculty of Pharmaceutical Science, Fukuoka University, Nanakuma, Johnan-ku, Fukuoka, 814-01, Japan
,
A. Nagamatsu Faculty of Pharmaceutical Science, Fukuoka University, Nanakuma, Johnan-ku, Fukuoka, 814-01, Japan
&
H. Shimeno Faculty of Pharmaceutical Science, Fukuoka University, Nanakuma, Johnan-ku, Fukuoka, 814-01, Japan
Pages 603-611 | Received 09 Dec 1993, Published online: 27 Aug 2009

Citations (15)

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S. Uno, M. Uraki, H. Komura, H. Ikuta, A. Kawase & M. Iwaki. (2008) Impaired intrinsic chiral inversion activity of ibuprofen in rats with adjuvant-induced arthritis. Xenobiotica 38:11, pages 1410-1421.
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S. Uno, A. Fujii, H. Komura, A. Kawase & M. Iwaki. (2008) Prediction of metabolic clearance of diclofenac in adjuvant-induced arthritis rats using a substrate depletion assay. Xenobiotica 38:5, pages 482-495.
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M. Achira, R. Totsuka, H. Fujimura & T. Kume. (2002) Decreased hepatobiliary transport of methotrexate in adjuvant arthritis rats. Xenobiotica 32:12, pages 1151-1160.
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M. Achira, R. Totsuka & T. Kume. (2002) Differences in pharmacokinetics and hepatobiliary transport of a novel anti-inflammatory agent between normal and adjuvant arthritis rats. Xenobiotica 32:12, pages 1139-1149.
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A. Toda, T. Kihara, N. Ono, A. Nagamatsu & H. Shimeno. (1996) Liver haem metabolism in adjuvant-induced arthritic rats. Xenobiotica 26:4, pages 415-423.
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Articles from other publishers (10)

Eleni A. Rekka, Panos N. Kourounakis & Maria Pantelidou. (2019) Xenobiotic Metabolising Enzymes: Impact on Pathologic Conditions, Drug Interactions and Drug Design. Current Topics in Medicinal Chemistry 19:4, pages 276-291.
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Misato Uraki, Atsushi Kawase, Hiroyuki Sayama, Yuka Matsushima & Masahiro Iwaki. (2017) Effects of Adjuvant-Induced Inflammation on Disposition of Diclofenac and Its Metabolites in Perfused Rat Liver. Journal of Pharmaceutical Sciences 106:4, pages 1175-1182.
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Hiroyuki Ikuta, Atsushi Kawase & Masahiro Iwaki. (2017) Stereoselective Pharmacokinetics and Chiral Inversion of Ibuprofen in Adjuvant-induced Arthritic Rats. Drug Metabolism and Disposition 45:3, pages 316-324.
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Nobukazu Ryu, Hiroki Tanabe, Toshiaki Makino, Hajime Mizukami & Makoto Inoue. (2007) Shosaikoto (a Kampo medicine) modulates changes in cytochrome P450 caused by Mycobacterium butyricum injection. Journal of Natural Medicines 61:3, pages 342-348.
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Denis Projean, Sophie Dautrey, Huy Khan Vu, Thierry Groblewski, Jean-Louis Brazier & Julie Ducharme. (2005) Selective Downregulation of Hepatic Cytochrome P450 Expression and Activity in a Rat Model of Inflammatory Pain. Pharmaceutical Research 22:1, pages 62-70.
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Pierre-Louis Toutain, Nadege Reymond, Valerie Laroute, Patrice Garcia, Marie-Agnes Popot, Yves Bonnaire, Alexandra Hirsch & Rudiger Narbe. (2004) Pharmacokinetics of meloxicam in plasma and urine of horses. American Journal of Veterinary Research 65:11, pages 1542-1547.
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Meguru Achira, Ryuichi Totsuka, Hisako Fujimura & Toshiyuki Kume. (2002) Tissue-specific regulation of expression and activity of P-glycoprotein in adjuvant arthritis rats. European Journal of Pharmaceutical Sciences 16:1-2, pages 29-36.
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Kenneth W Renton. (2001) Alteration of drug biotransformation and elimination during infection and inflammation. Pharmacology & Therapeutics 92:2-3, pages 147-163.
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P. L. Toutain, C. C. Cester, T. Haak & V. Laroute. (2008) A pharmacokinetic/pharmacodynamic approach vs. a dose titration for the determination of a dosage regimen: the case of nimesulide, a Cox‐2 selective nonsteroidal anti‐inflammatory drug in the dog. Journal of Veterinary Pharmacology and Therapeutics 24:1, pages 43-55.
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Anneke C Blackburn, William F Doe & Gary D Buffinton. (1998) Salicylate Hydroxylation as an Indicator of Hydroxyl Radical Generation in Dextran Sulfate-Induced Colitis. Free Radical Biology and Medicine 25:3, pages 305-313.
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