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Liping Li, Siyuan Sun, Yayun Weng, Feifeng Song, Sisi Zhou, Mengru Bai, Hui Zhou, Su Zeng & Huidi Jiang. (2016) Interaction of six protoberberine alkaloids with human organic cation transporters 1, 2 and 3. Xenobiotica 46:2, pages 175-183.
Read now
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Noriaki Sakai & Mayumi Ishizuka. (2009) Impact of rat P450 genetic polymorphism on diazepam metabolism. Expert Opinion on Drug Metabolism & Toxicology 5:11, pages 1421-1433.
Read now
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H. M. Jones, G. Nicholls & J. B. Houston. (2005) Impact of end-product inhibition on the determination of in vitro metabolic clearance. Xenobiotica 35:5, pages 439-454.
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D. M. CROSS & M. K. BAYLISS. (2000) A COMMENTARY ON THE USE OF HEPATOCYTES IN DRUG METABOLISM STUDIES DURING DRUG DISCOVERY AND DEVELOPMENT*. Drug Metabolism Reviews 32:2, pages 219-240.
Read now
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M. K. BAYLISS. (1999) Utility of hepatocytes to model species differences in the metabolism of loxtidine and to predict pharmacokinetic parameters in rat, dog and man. Xenobiotica 29:3, pages 253-268.
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J. Brian Houston & David J. Carlile. (1997) Prediction of Hepatic Clearance from Microsomes, Hepatocytes, and Liver Slices. Drug Metabolism Reviews 29:4, pages 891-922.
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K. Zomorodi & J. B. Houston. (1997) Selectivity of omeprazole inhibition towards rat liver cytochromes P450. Xenobiotica 27:1, pages 49-58.
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P. SANWALD-DUCRAY & J. DOW*. (1997) Prediction of the pharmacokinetic parameters of reduced- dolasetron in man using in vitro-in vivo and interspecies allometric scaling. Xenobiotica 27:2, pages 189-201.
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P. D. Worboys, B. Brennan, A. Bradbury & J. B. Houston. (1996) Metabolite kinetics of ondansetron in rat. Comparison of hepatic microsomes, isolated hepatocytes and liver slices, with in vivo disposition. Xenobiotica 26:9, pages 897-907.
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Articles from other publishers (22)
Priyanka R. Kulkarni, Amir S. Youssef & Aneesh A. Argikar. 2021. Enzyme Kinetics in Drug Metabolism. Enzyme Kinetics in Drug Metabolism
369
417
.
Jin Dong & Miki Susanto Park. (2018) Discussions on the hepatic well-stirred model: Re-derivation from the dispersion model and re-analysis of the lidocaine data. European Journal of Pharmaceutical Sciences 124, pages 46-60.
Crossref
Crossref
Helen Musther, Matthew D. Harwood, Jiansong Yang, David B. Turner, Amin Rostami-Hodjegan & Masoud Jamei. (2017) The Constraints, Construction, and Verification of a Strain-Specific Physiologically Based Pharmacokinetic Rat Model. Journal of Pharmaceutical Sciences 106:9, pages 2826-2838.
Crossref
Crossref
Núbia C. de Paula, Kelly C.F. Araujo Cordeiro, Paula L. de Melo Souza, Diogo F. Nogueira, Diego B. da Silva e Sousa, Maísa B. Costa, François Noël & Valéria de Oliveira. (2015) Biosynthesis of human diazepam and clonazepam metabolites. Bioorganic & Medicinal Chemistry Letters 25:5, pages 1026-1029.
Crossref
Crossref
Liping Li, Meijuan Tu, Xi Yang, Siyuan Sun, Xiaodan Wu, Hui Zhou, Su Zeng & Huidi Jiang. (2014) The Contribution of Human OCT1, OCT3, and CYP3A4 to Nitidine Chloride–Induced Hepatocellular Toxicity. Drug Metabolism and Disposition 42:7, pages 1227-1234.
Crossref
Crossref
Urban Fagerholm. (2007) Prediction of human pharmacokinetics—evaluation of methods for prediction of hepatic metabolic clearance. Journal of Pharmacy and Pharmacology 59:6, pages 803-828.
Crossref
Crossref
Qiao Jinping, Hou Peiling, Li Yawei & Zeper Abliz. (2003)
Effects of the aqueous extract from
Salvia miltiorrhiza
Bge on the pharmacokinetics of diazepam and on liver microsomal cytochrome P450 enzyme activity in rats
. Journal of Pharmacy and Pharmacology 55:8, pages 1163-1167.
Crossref
Crossref
Masato Chiba, Yasuyuki Ishii & Yuichi Sugiyama. (2009) Prediction of Hepatic Clearance in Human From In Vitro Data for Successful Drug Development. The AAPS Journal 11:2.
Crossref
Crossref
Mónica Garca‐Lóapez, Susana Yenes, Helmut Buschmann & Antoni Torrens. 2007. Antidepressants, Antipsychotics, Anxiolytics. Antidepressants, Antipsychotics, Anxiolytics
951
1087
.
J.V. Turner & S. Agatonovic-Kustrin. 2007. Comprehensive Medicinal Chemistry II. Comprehensive Medicinal Chemistry II
699
724
.
Hannah M. Jones & J. Brian Houston. (2004) SUBSTRATE DEPLETION APPROACH FOR DETERMINING IN VITRO METABOLIC CLEARANCE: TIME DEPENDENCIES IN HEPATOCYTE AND MICROSOMAL INCUBATIONS. Drug Metabolism and Disposition 32:9, pages 973-982.
Crossref
Crossref
Hannah M. Jones, David Hallifax & J. Brian Houston. (2004) QUANTITATIVE PREDICTION OF THE IN VIVO INHIBITION OF DIAZEPAM METABOLISM BY OMEPRAZOLE USING RAT LIVER MICROSOMES AND HEPATOCYTES. Drug Metabolism and Disposition 32:5, pages 572-580.
Crossref
Crossref
Michael W. Sinz. 2004. Applications of Pharmacokinetic Principles in Drug Development. Applications of Pharmacokinetic Principles in Drug Development
75
132
.
Daniel R. Mudra & Andrew Parkinson. (2001) Preparation of Hepatocytes. Current Protocols in Toxicology 8:1.
Crossref
Crossref
Ivan Nestorov, David Carlile, Hannah Jones, Brian Houston & Malcolm Rowland. (2000) Incorporating Variability and Uncertainty Into Interspecies Scaling of Pharmacokinetics. IFAC Proceedings Volumes 33:3, pages 97-102.
Crossref
Crossref
Barbra H. Stewart & Yi Wang. 2000.
299
307
.
Martin K. Bayliss & David M. Cross. 2000. The Hepatocyte Review. The Hepatocyte Review
365
389
.
Michael Sinz. 1999. Handbook of Drug Metabolism. Handbook of Drug Metabolism
401
424
.
Sean Ekins, Jukka Maenpää & Steven Wrighton. 1999. Handbook of Drug Metabolism. Handbook of Drug Metabolism
363
399
.
J.B. Houston & D.J. Carlile. (1997) Incorporation of in vitro drug metabolism data into physiologically-based pharmacokinetic models. Toxicology in Vitro 11:5, pages 473-478.
Crossref
Crossref
Chandrani Gunaratna & Peter T Kissinger. (1997) Application of microdialysis to study the in vitro metabolism of drugs in liver microsomes. Journal of Pharmaceutical and Biomedical Analysis 16:2, pages 239-248.
Crossref
Crossref
T.H. Lave, S. Dupin, C. Schmitt, R.C. Chou, D. Jaeck & Ph. Coassolo. (1997) Integration of in Vitro Data into Allometric Scaling to Predict Hepatic Metabolic Clearance in Man: Application to 10 Extensively Metabolized Drugs. Journal of Pharmaceutical Sciences 86:5, pages 584-590.
Crossref
Crossref