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Xenobiotica
the fate of foreign compounds in biological systems
Volume 25, 1995 - Issue 11
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Research Article

Dog liver microsomal P450 enzyme-mediated toluene biotransformation

H. Hanioka Division of Environmental Chemistry, National Institute of Health Sciences, 1–18–1 Kamiyoga, Setagaya-ku, Tokyo, 158, Japan
,
M. Hamamura Safety Assessment Laboratory, Panapharm Laboratories Co., Ltd., 1285 Kurisaki-cho, Uto, Kumamoto, 869–04, Japan
,
K. Kakino Safety Assessment Laboratory, Panapharm Laboratories Co., Ltd., 1285 Kurisaki-cho, Uto, Kumamoto, 869–04, Japan
,
H. Ogata Safety Assessment Laboratory, Panapharm Laboratories Co., Ltd., 1285 Kurisaki-cho, Uto, Kumamoto, 869–04, Japan
,
H. Jinno Division of Environmental Chemistry, National Institute of Health Sciences, 1–18–1 Kamiyoga, Setagaya-ku, Tokyo, 158, Japan
,
A. Takahashi Food and Drug Safety Center, Hatano Research Institute, 729-5 Ochiai, Hadano, Kanagawa, 257, Japan
,
T. Nishimura Division of Environmental Chemistry, National Institute of Health Sciences, 1–18–1 Kamiyoga, Setagaya-ku, Tokyo, 158, Japan
&
M. Ando Division of Environmental Chemistry, National Institute of Health Sciences, 1–18–1 Kamiyoga, Setagaya-ku, Tokyo, 158, Japan
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Pages 1207-1217 | Received 13 May 1995, Published online: 22 Sep 2008

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Thomas RF Scior, Evelyn Martínez-Morales, Silvia L Cruz & Eduardo M Salinas-Stefanon. (2009) In silico modeling of toluene binding site in the pore of voltage-gate sodium channel. Journal of Receptor, Ligand and Channel Research 2, pages 1-2.
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Jing Zhang, Yonghui Tian, Zewei Luo, Cheng Qian, Wenwen Li & Yixiang Duan. (2021) Breath volatile organic compound analysis: an emerging method for gastric cancer detection. Journal of Breath Research 15:4, pages 044002.
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Terrell L. Hodge, Blair R. Szymczyna & Todd J. Barkman. 2015. Algebraic and Discrete Mathematical Methods for Modern Biology. Algebraic and Discrete Mathematical Methods for Modern Biology 261 292 .
Ji-Young Lee, Seungki Kim, Jong-Tae Lee, Jong-Ho Choi, Jeongae Lee & Heesoo Pyo. (2012) Rapid Determination of Volatile Organic Compounds in Human Whole Blood Using Static Headspace Sampling with Gas Chromatography and Mass Spectrometry. Bulletin of the Korean Chemical Society 33:12, pages 3963-3970.
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Anneleen Pletinck, Raymond Vanholder & Griet Glorieux. 2012. Uremic Toxins. Uremic Toxins 77 86 .
Bobae Kwon, Siwon Kim, Sosun Kim, Dong-Kye Lee, Yu-Jin Park, Myung-Duck Kim, Jae-Shin Lee & Suhkmann Kim. (2011) 1H NMR spectroscopic identification of a glue sniffing biomarker. Forensic Science International 209:1-3, pages 120-125.
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Nita Tudorachi & Aurica P. Chiriac. (2011) Poly(vinyl alcohol-co-lactic acid)/Hydroxyapatite Composites: Synthesis and Characterization. Journal of Polymers and the Environment 19:2, pages 546-558.
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Nobumitsu Hanioka, Maki Yamamoto, Toshiko Tanaka-Kagawa, Hideto Jinno & Shizuo Narimatsu. (2009) Functional characterization of human cytochrome P450 2E1 allelic variants: in vitro metabolism of benzene and toluene by recombinant enzymes expressed in yeast cells. Archives of Toxicology 84:5, pages 363-371.
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Janice S. Lee, William O. Ward, Douglas C. Wolf, James W. Allen, Camilla Mills, Michael J. DeVito & J. Christopher Corton. (2008) Coordinated Changes in Xenobiotic Metabolizing Enzyme Gene Expression in Aging Male Rats. Toxicological Sciences 106:1, pages 263-283.
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H. Umesha Shetty, Sami S. Zoghbi, Jeih-San Liow, Masanori Ichise, Jinsoo Hong, John L. Musachio, Christer Halldin, Jurgen Seidel, Robert B. Innis & Victor W. Pike. (2006) Identification and regional distribution in rat brain of radiometabolites of the dopamine transporter PET radioligand [11C]PE2I. European Journal of Nuclear Medicine and Molecular Imaging 34:5, pages 667-678.
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Wolfgang Völkel, Thomas Colnot, Ute M.D. Schauer, Thomas H. Broschard & Wolfgang Dekant. (2006) Toxicokinetics and biotransformation of 3-(4-methylbenzylidene)camphor in rats after oral administration. Toxicology and Applied Pharmacology 216:2, pages 331-338.
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. (2016) Final Report on the Safety Assessment of Sodium p -Chloro- m -Cresol, p -Chloro- m -Cresol, Chlorothymol, Mixed Cresols, m -Cresol, o -Cresol, p -Cresol, Isopropyl Cresols, Thymol, o -Cymen-5-ol, and Carvacrol1. International Journal of Toxicology 25:1_suppl, pages 29-127.
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Taku Nakano, Sally Kawabata, Tamami Sugihara, Noriko Agatsuma, Hiroko Kakuda & Yoshihiro Mori. (2003) On the Mechanism of the Oxidation of Toluenes in Artificial P450 Model Systems: Formation of Benzyl Alcohols, Benzaldehydes, and Phenols. Bulletin of the Chemical Society of Japan 76:12, pages 2353-2360.
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Raymond Vanholder, Rita De Smet & Gerrit Lesaffer. (1999) p-Cresol: a toxin revealing many neglected but relevant aspects of uraemic toxicity. Nephrology Dialysis Transplantation 14:12, pages 2813-2815.
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