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Xenobiotica
the fate of foreign compounds in biological systems
Volume 25, 1995 - Issue 1
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Research Article

Sex-dependent and independent renal excretion of nilvadipine metabolites in rat: evidence for a sex-dependent active secretion in kidney

S. Terashita Product Development Research Laboratories, Fujisawa Pharmaceutical Co., Ltd, 2–1 Kashima, Yodogawa-ku, Osaka, 532, Japan
,
T. Sawamoto Product Development Research Laboratories, Fujisawa Pharmaceutical Co., Ltd, 2–1 Kashima, Yodogawa-ku, Osaka, 532, Japan
,
S. Deguchi Product Development Research Laboratories, Fujisawa Pharmaceutical Co., Ltd, 2–1 Kashima, Yodogawa-ku, Osaka, 532, Japan
,
Y. Tokuma Product Development Research Laboratories, Fujisawa Pharmaceutical Co., Ltd, 2–1 Kashima, Yodogawa-ku, Osaka, 532, Japan
&
T. Hata Product Development Research Laboratories, Fujisawa Pharmaceutical Co., Ltd, 2–1 Kashima, Yodogawa-ku, Osaka, 532, Japan
Pages 37-47 | Received 14 Jul 1994, Published online: 22 Sep 2008

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Naoki Kamada, Keigo Yamada, Masaaki Odomi, Tadashi Mukai, Toru Nishibayashi, Ken-ichi Ogawara, Toshikiro Kimura & Kazutaka Higaki. (2011) Sex differences in pharmacokinetics of cilostazol in rats. Xenobiotica 41:10, pages 903-913.
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H. Nakajima, T. Nakanishi, H. Naba, K. Nakai, S. Matsumoto, K. Nagasawa, K. Ida, T. Ogihara & N. Ohzawa. (2002) Studies on the metabolic fate of M17055, a novel diuretic (6). Assessment for drug-drug interactions of M17055 in metabolism, distribution and excretion. Xenobiotica 32:12, pages 1161-1172.
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Suk K. Hong, Dianne K. Anestis, Monica A. Valentovic, John G. Ball, Patrick I. Brown & Gary O. Rankin. (2001) GENDER DIFFERENCES IN THE POTENTIATION OF N-(3,5-DICHLOROPHENYL)SUCCINIMIDE METABOLITE NEPHROTOXICITY BY PHENOBARBITAL. Journal of Toxicology and Environmental Health, Part A 64:3, pages 241-256.
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H. KOBAYASHI*S. KOBAYASHI. (1998) Absorption, distribution, metabolism and excretion of 14C-labelled enantiomers of the calcium channel blocker benidipine after oral administration to rat. Xenobiotica 28:2, pages 179-197.
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Rachel Rogers Worley & Jeffrey Fisher. (2015) Application of physiologically-based pharmacokinetic modeling to explore the role of kidney transporters in renal reabsorption of perfluorooctanoic acid in the rat. Toxicology and Applied Pharmacology 289:3, pages 428-441.
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Ivan Sabolić, Abdul R. Asif, Wolfgang E. Budach, Christoph Wanke, Andrew Bahn & Gerhard Burckhardt. (2007) Gender differences in kidney function. Pflügers Archiv - European Journal of Physiology 455:3, pages 397-429.
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David C. PrydeGraham N. MawSimon PlankenMichelle Y. PlattsVivienne SandersonMartin CorlessAlan StobieChristopher G. BarberRachel RussellLaura FosterLaura BarkerChristopher WaymanPiet Van Der GraafPeter StaceyDebbie MorrenChristopher KohlKevin BeaumontSara CoggonMichael Tute. (2006) Novel Selective Inhibitors of Neutral Endopeptidase for the Treatment of Female Sexual Arousal Disorder. Synthesis and Activity of Functionalized Glutaramides. Journal of Medicinal Chemistry 49:14, pages 4409-4424.
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Carlotta E. Groves, Wendy B. Suhre, Nathan J. Cherrington & Stephen H. Wright. (2006) Sex Differences in the mRNA, Protein, and Functional Expression of Organic Anion Transporter (Oat) 1, Oat3, and Organic Cation Transporter (Oct) 2 in Rabbit Renal Proximal Tubules. Journal of Pharmacology and Experimental Therapeutics 316:2, pages 743-752.
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Akemi Shimizu, Mika Miyoshi, Masami Sugie, Jun Ueyama, Takuji Yamaguchi, Toshinobu Sasaki, Kenzo Takagi, Mingji Jin, Ken-ichi Miyamoto, Akira Tsuji & Takaaki Hasegawa. (2004) Possible involvement of P-glycoprotein in renal excretion of pazufloxacin in rats. European Journal of Pharmacology 501:1-3, pages 151-159.
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Masami Sugie, Emiko Asakura, Ying Lan Zhao, Shoko Torita, Masayuki Nadai, Kenji Baba, Kiyoyuki Kitaichi, Kenji Takagi, Kenzo Takagi & Takaaki Hasegawa. (2004) Possible Involvement of the Drug Transporters P Glycoprotein and Multidrug Resistance-Associated Protein Mrp2 in Disposition of Azithromycin. Antimicrobial Agents and Chemotherapy 48:3, pages 809-814.
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Marilyn E. Morris, Hwa-Jeong Lee & Lisa M. Predko. (2003) Gender Differences in the Membrane Transport of Endogenous and Exogenous Compounds. Pharmacological Reviews 55:2, pages 229-240.
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Yasumasa GotohYukio Kato, Bruno Stieger, Peter J. Meier & Yuichi Sugiyama. (2002) Gender difference in the Oatp1-mediated tubular reabsorption of estradiol 17β- d -glucuronide in rats . American Journal of Physiology-Endocrinology and Metabolism 282:6, pages E1245-E1254.
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Efim B. Berkhin & Michael H. Humphreys. (2001) Regulation of renal tubular secretion of organic compounds. Kidney International 59:1, pages 17-30.
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Jordi To‐Figueras, Jesús Gómez‐Catalán, Carme Barrot, Miquel Rodamilans & Jacint Corbella. (2009) Disappearance and Sex‐Dependent Excretion of S‐Pentachlorophenyl‐N‐acetyl‐L‐cysteine in the Rat. Pharmacology & Toxicology 77:6, pages 412-413.
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