Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 25, 1995 - Issue 1
37
Views
20
CrossRef citations to date
0
Altmetric
Research Article

Cytotoxicity induced by N-methyl-N′-nitro-N-nitrosoguanidine may involve S-nitrosyl glutathione and nitric oxide

&
Pages 91-101 | Received 21 Jun 1994, Published online: 22 Sep 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Walied M. Alarif, Seif-Eldin N. Ayyad, Sufian M. El-Assouli & Sultan S. Al-Lihaibi. (2012) Antigenotoxic ketosteroid from the red algae Jania adhaerens . Natural Product Research 26:9, pages 785-791.
Read now
Lisheng Wang, Junhong Sun, Li Li, Colin Harbour, Douglas Mears, Nick Koutalistras & Ag Ross Sheil. (2000) Factors Affecting Hepatocyte Viability and Cypial Activity During Encapsulation. Artificial Cells, Blood Substitutes, and Biotechnology 28:3, pages 215-227.
Read now
Pierre Moffatt & Francine Denizeau. (1997) Metallothionein in Physiological and Physiopathological Processes. Drug Metabolism Reviews 29:1-2, pages 261-307.
Read now
Klaus D. Kröncke & Victoria Kolb-Bachofen. (1996) Streptozotocin is not a Spontaneous NO Donor. Free Radical Research 24:2, pages 77-80.
Read now

Articles from other publishers (16)

R. Morita, H. Hishinuma, H. Ohyama, R. Mega, T. Ohta, N. Nakagawa, Y. Agari, K. Fukui, A. Shinkai, S. Kuramitsu & R. Masui. (2011) An alkyltransferase-like protein from Thermus thermophilus HB8 affects the regulation of gene expression in alkylation response. Journal of Biochemistry 150:3, pages 327-339.
Crossref
N. A. Sanina & S. M. Aldoshin. (2012) Structure and properties of iron nitrosyl complexes with functionalized sulfur-containing ligands. Russian Chemical Bulletin 60:7, pages 1223-1251.
Crossref
Bor-Sen Wang, Pin-Der Duh, She-Ching Wu & Ming-Hsing Huang. (2011) Effects of the aqueous extract of sugarcane leaves on antimutation and nitric oxide generation. Food Chemistry 124:2, pages 495-500.
Crossref
Pin-Der Duh, She-Ching Wu, Lee-Wen Chang, Heuy-Ling Chu, Wen-Jye Yen & Bor-Sen Wang. (2009) Effects of three biological thiols on antimutagenic and antioxidant enzyme activities. Food Chemistry 114:1, pages 87-92.
Crossref
Ben Buelow, Yumei Song & Andrew M. Scharenberg. (2008) The Poly(ADP-ribose) Polymerase PARP-1 Is Required for Oxidative Stress-induced TRPM2 Activation in Lymphocytes. Journal of Biological Chemistry 283:36, pages 24571-24583.
Crossref
P?ter Bai, Csaba Heged?s, Katalin Erd?lyi, ?va Szab?Edina Bakondi, Szabolcs Gergely, Csaba Szab?L?szl? Vir?g. (2007) Protein tyrosine nitration and poly(ADP-ribose) polymerase activation in N-methyl-N-nitro-N-nitrosoguanidine-treated thymocytes: Implication for cytotoxicity. Toxicology Letters 170:3, pages 203-213.
Crossref
Anne-Laure Perraud, Christina L. Takanishi, Betty Shen, Shin Kang, Megan K. Smith, Carsten Schmitz, Heather M. Knowles, Dana Ferraris, Weixing Li, Jie Zhang, Barry L. Stoddard & Andrew M. Scharenberg. (2005) Accumulation of Free ADP-ribose from Mitochondria Mediates Oxidative Stress-induced Gating of TRPM2 Cation Channels. Journal of Biological Chemistry 280:7, pages 6138-6148.
Crossref
Giuliano Dodoni, Marcella Canton, Valeria Petronilli, Paolo Bernardi & Fabio Di Lisa. (2004) Induction of the mitochondrial permeability transition by the DNA alkylating agent N-methyl-N′-nitro-N-nitrosoguanidine. Sorting cause and consequence of mitochondrial dysfunction. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1658:1-2, pages 58-63.
Crossref
Isabelle Valentin, Murielle Philippe, Jean-Claude Lhuguenot & Marie-Christine Chagnon. (2001) Uridine uptake inhibition as a cytotoxicity test for a human hepatoma cell line (HepG2 cells): comparison with the neutral red assay. Toxicology 158:3, pages 127-139.
Crossref
H Kwak. (2000) Interrelationship of apoptosis, mutation, and cell proliferation in N-methyl-N?-nitro-N-nitrosoguanidine (MNNG)-induced medaka carcinogenesis model. Aquatic Toxicology 50:4, pages 317-329.
Crossref
Tzyh-Chyuan Hour, Shoei-Yn Lin Shiau & Jen-Kun Lin. (1999) Suppression of N-methyl-N?-nitro-N-nitrosoguanidine- and S-nitrosoglutathione-induced apoptosis by Bcl-2 through inhibiting glutathione-S-transferase ? in NIH3T3 cells. Toxicology Letters 110:3, pages 191-202.
Crossref
C. Beudot, M.P. De Méo, D. Dauzonne, R. Elias, M. Laget, H. Guiraud, G. Balansard & G. Duménil. (1998) Evaluation of the mutagenicity and antimutagenicity of forty-two 3-substituted flavones in the Ames test. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 417:2-3, pages 141-153.
Crossref
C.L Mitchelmore & J.K Chipman. (1998) Detection of DNA strand breaks in brown trout (Salmo trutta) hepatocytes and blood cells using the single cell gel electrophoresis (comet) assay. Aquatic Toxicology 41:1-2, pages 161-182.
Crossref
Hossein Niknahad & Peter J. O'Brien. (1996) Involvement of nitric oxide in nitroprusside-induced hepatocyte cytotoxicity. Biochemical Pharmacology 51:8, pages 1031-1039.
Crossref
Csaba SzabÓ. (1996) DNA strand breakage and activation of poly-ADP ribosyltransferase: A cytotoxic pathway triggered by peroxynitrite. Free Radical Biology and Medicine 21:6, pages 855-869.
Crossref
D. V. Parke. (1995) Free radicals, nitroso compounds, and safer NSAIDs. Inflammopharmacology 3:3, pages 197-199.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.