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Xenobiotica
the fate of foreign compounds in biological systems
Volume 25, 1995 - Issue 6
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Original Article

Enantioselective metabolism and pharmacokinetics of Casodex in the male rat

D. McKillop Drug Kinetics Group, Safety of Medicines Department, ZENECA Pharmaceuticals, Alderley Park, Macclesfield, SK10 4TG, UK
,
P. J. Simons Drug Kinetics Group, Safety of Medicines Department, ZENECA Pharmaceuticals, Alderley Park, Macclesfield, SK10 4TG, UK
,
I. D. Cockshott Drug Kinetics Group, Safety of Medicines Department, ZENECA Pharmaceuticals, Alderley Park, Macclesfield, SK10 4TG, UK
,
S. J. Hill Drug Kinetics Group, Safety of Medicines Department, ZENECA Pharmaceuticals, Alderley Park, Macclesfield, SK10 4TG, UK
,
J. R. Harding Drug Kinetics Group, Safety of Medicines Department, ZENECA Pharmaceuticals, Alderley Park, Macclesfield, SK10 4TG, UK
,
K. J. Cooper Drug Kinetics Group, Safety of Medicines Department, ZENECA Pharmaceuticals, Alderley Park, Macclesfield, SK10 4TG, UK
&
D. C. Jones Drug Kinetics Group, Safety of Medicines Department, ZENECA Pharmaceuticals, Alderley Park, Macclesfield, SK10 4TG, UK
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Pages 623-633 | Received 19 Dec 1994, Published online: 27 Aug 2009

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Guy Felix & Alain Berthod. (2007) Commercial Chiral Stationary Phases for the Separations of Clinical Racemic Drugs. Separation & Purification Reviews 36:4, pages 285-481.
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D. McKILLOP*C. J. BUTTERS, S. J. HILL, P. J. SIMONS, T. L. EDWARDS & S. E. DOUGHTY. (1998) Enzyme-inducing effects of bicalutamide in mouse, rat and dog. Xenobiotica 28:5, pages 465-478.
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Articles from other publishers (7)

Dante Rojas, Gaud Dervilly-Pinel, Nora Cesbron, Mylène Penot, Alexandre Sydor, Stéphanie Prévost & Bruno Le Bizec. (2017) Selective androgen receptor modulators: comparative excretion study of bicalutamide in bovine urine and faeces. Drug Testing and Analysis 9:7, pages 1017-1025.
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Lin Xu. 2014. Handbook of Metabolic Pathways of Xenobiotics. Handbook of Metabolic Pathways of Xenobiotics 1 4 .
Kuldeep Sharma, Gopal V. Pawar, Sanjeev Giri, Sriram Rajagopal & Ramesh Mullangi. (2012) Development and validation of a highly sensitive LC‐MS/MS‐ESI method for the determination of bicalutamide in mouse plasma: application to a pharmacokinetic study. Biomedical Chromatography 26:12, pages 1589-1595.
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SeungHwan Lee, Yong-Ju Chung, Bo-Hyung Kim, Jun-Hwa Shim, Seo-Hyun Yoon, Sang-Goo Shin, In-Jin Jang & Kyung-Sang Yu. (2009) Comparative pharmacokinetic evaluation of two formulations of bicalutamide 50-mg tablets: An open-label, randomized-sequence, single-dose, two-period crossover study in healthy Korean male volunteers. Clinical Therapeutics 31:12, pages 3000-3008.
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Juhyun Kim, Di Wu, Dong Jin Hwang, Duane D. Miller & James T. Dalton. (2005) The Para Substituent of S -3-(Phenoxy)-2-hydroxy-2-methyl- N -(4-nitro-3-trifluoromethyl-phenyl)-propionamides Is a Major Structural Determinant of in Vivo Disposition and Activity of Selective Androgen Receptor Modulators . Journal of Pharmacology and Experimental Therapeutics 315:1, pages 230-239.
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Ian D Cockshott. (2004) Bicalutamide. Clinical Pharmacokinetics 43:13, pages 855-878.
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Donghua Yin, Huiping Xu, Yali He, Leonid I. Kirkovsky, Duane D. Miller & James T. Dalton. (2003) Pharmacology, Pharmacokinetics, and Metabolism of Acetothiolutamide, a Novel Nonsteroidal Agonist for the Androgen Receptor. Journal of Pharmacology and Experimental Therapeutics 304:3, pages 1323-1333.
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