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Xenobiotica
the fate of foreign compounds in biological systems
Volume 25, 1995 - Issue 7
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Original Article

Central role of radical cations in metabolic activation of polycyclic aromatic hydrocarbons

&
Pages 677-688 | Received 12 Nov 1994, Published online: 27 Aug 2009

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Matthew Reed, Michael Monske, Fredine Lauer, Stephen Meserole, Jerry Born & Scott Burchiel. (2003) Benzo[a]Pyrene Diones are Produced by Photochemical and Enzymatic Oxidation and Induce Concentration-Dependent Decreases in the Proliferative State of Human Pulmonary Epithelial Cells. Journal of Toxicology and Environmental Health, Part A 66:13, pages 1189-1205.
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Ercole Cavalieri & Eleanor Rogan. (1996) The Primary Role of Apurinic Sites in Tumor Initiation. Polycyclic Aromatic Compounds 10:1-4, pages 251-258.
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Sushmita Sen & Jeffrey M. Field. 2013. 83 127 .
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Sergio Manzetti. (2012) Ecotoxicity of polycyclic aromatic hydrocarbons, aromatic amines, and nitroarenes through molecular properties. Environmental Chemistry Letters 10:4, pages 349-361.
Crossref
K. John, M. M. Pratt, F. A. Beland, M. I. Churchwell, G. McMullen, O. A. Olivero, I. P. Pogribny & M. C. Poirier. (2012) Benzo[a]pyrene (BP) DNA adduct formation in DNA repair-deficient p53 haploinsufficient [Xpa(-/-)p53(+/-)] and wild-type mice fed BP and BP plus chlorophyllin for 28 days. Carcinogenesis 33:11, pages 2236-2241.
Crossref
Lisbeth K. Siddens, Andrew Larkin, Sharon K. Krueger, Christopher A. Bradfield, Katrina M. Waters, Susan C. Tilton, Cliff B. Pereira, Christiane V. Löhr, Volker M. Arlt, David H. Phillips, David E. Williams & William M. Baird. (2012) Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse. Toxicology and Applied Pharmacology 264:3, pages 377-386.
Crossref
Sushmita Sen, Pratik Bhojnagarwala, Lauren Francey, Ding Lu, Trevor M. Penning & Jeffrey Field. (2012) p53 Mutagenesis by Benzo[ a ]pyrene Derived Radical Cations . Chemical Research in Toxicology 25:10, pages 2117-2126.
Crossref
Prashant Kumar Jaiswal, Shaili Srivastava, Jyotsana Gupta & Indu Shekhar Thakur. (2012) Dibenzofuran induces oxidative stress, disruption of trans-mitochondrial membrane potential (ΔΨm) and G1 arrest in human hepatoma cell line. Toxicology Letters 214:2, pages 137-144.
Crossref
Konstantinos Grintzalis, Christos D. Georgiou & Stefanos Dailianis. (2012) Total thiol redox status as a potent biomarker of PAH-mediated effects on mussels. Marine Environmental Research 81, pages 26-34.
Crossref
Anhui Wu, Daiwang Xu, Ding Lu, Trevor M. Penning, Ian A. Blair & Ronald G. Harvey. (2012) Synthesis of 13C4-labelled oxidized metabolites of the carcinogenic polycyclic aromatic hydrocarbon benzo[a]pyrene. Tetrahedron 68:35, pages 7217-7233.
Crossref
Li Zhang, Meng Huang, Ian A. Blair & Trevor M. Penning. (2012) Detoxication of Benzo[a]pyrene-7,8-dione by Sulfotransferases (SULTs) in Human Lung Cells. Journal of Biological Chemistry 287:35, pages 29909-29920.
Crossref
Gabriela L. Borosky & Kenneth K. Laali. (2012) In Silico study of carcinogenic o-Quinone metabolites derived from polycyclic aromatic hydrocarbons (PAHs). Journal of Physical Organic Chemistry 25:8, pages 720-728.
Crossref
Sherain N. Al-Subiai, Volker M. Arlt, Patricia E. Frickers, James W. Readman, Björn Stolpe, Jamie R. Lead, A. John Moody & Awadhesh N. Jha. (2012) Merging nano-genotoxicology with eco-genotoxicology: An integrated approach to determine interactive genotoxic and sub-lethal toxic effects of C60 fullerenes and fluoranthene in marine mussels, Mytilus sp.. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 745:1-2, pages 92-103.
Crossref
Meng Huang, Xiaojing Liu, Sankha S. Basu, Li Zhang, Mary E. Kushman, Ronald G. Harvey, Ian A. Blair & Trevor M. Penning. (2012) Metabolism and Distribution of Benzo[ a ]pyrene-7,8-dione (B[ a ]P-7,8-dione) in Human Lung Cells by Liquid Chromatography Tandem Mass Spectrometry: Detection of an Adenine B[ a ]P-7,8-dione Adduct . Chemical Research in Toxicology 25:5, pages 993-1003.
Crossref
Alexander V. LyubimovCurtis J. Omiecinski, Xi Yang & Elizabeth M. Laurenzana. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 30 .
Maciej Gawlik, Małgorzata B. Gawlik & Jerzy Brandys. (2012) The impact of Triton WR-1339 induced hyperlipidemia on the effects of benzo(a)pyrene or guaiacol on α- and γ-tocopherol pools and selected markers of pro-/antioxidative balance in rat plasma and erythrocytes. Environmental Toxicology and Pharmacology 33:3, pages 386-393.
Crossref
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 210 .
Zahidur Abedin, Sushmita Sen & Jeffrey Field. (2011) Aldo-Keto Reductases Protect Lung Adenocarcinoma Cells from the Acute Toxicity of B[ a ]P-7,8- trans -Dihydrodiol . Chemical Research in Toxicology 25:1, pages 113-121.
Crossref
Frank Henkler, Kristin Stolpmann & Andreas Luch. 2012. Molecular, Clinical and Environmental Toxicology. Molecular, Clinical and Environmental Toxicology 107 131 .
Carol A. Shultz, Amy M. Quinn, Jong-Heum Park, Ronald G. Harvey, Judy L. Bolton, Edmund Maser & Trevor M. Penning. (2011) Specificity of Human Aldo-Keto Reductases, NAD(P)H:Quinone Oxidoreductase, and Carbonyl Reductases to Redox-Cycle Polycyclic Aromatic Hydrocarbon Diones and 4-Hydroxyequilenin- o- quinone . Chemical Research in Toxicology 24:12, pages 2153-2166.
Crossref
Lin Wang, Luqing Pan, Na Liu, Dong Liu, Chaoqun Xu & Jingjing Miao. (2011) Biomarkers and bioaccumulation of clam Ruditapes philippinarum in response to combined cadmium and benzo[α]pyrene exposure. Food and Chemical Toxicology 49:12, pages 3407-3417.
Crossref
Ding Lu, Ronald G. Harvey, Ian A. Blair & Trevor M. Penning. (2011) Quantitation of Benzo[ a ]pyrene Metabolic Profiles in Human Bronchoalveolar (H358) Cells by Stable Isotope Dilution Liquid Chromatography–Atmospheric Pressure Chemical Ionization Mass Spectrometry . Chemical Research in Toxicology 24:11, pages 1905-1914.
Crossref
Meili Gao, Yongfei Li, Ying Sun, Jiangang Long, Yu Kong, Shuiyun Yang & Yili Wang. (2011) A common carcinogen benzo[a]pyrene causes p53 overexpression in mouse cervix via DNA damage. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 724:1-2, pages 69-75.
Crossref
Li Zhang, Yi Jin, Mo Chen, Meng Huang, Ronald G. Harvey, Ian A. Blair & Trevor M. Penning. (2011) Detoxication of Structurally Diverse Polycyclic Aromatic Hydrocarbon (PAH) o-Quinones by Human Recombinant Catechol-O-methyltransferase (COMT) via O-Methylation of PAH Catechols. Journal of Biological Chemistry 286:29, pages 25644-25654.
Crossref
Romualdo Benigni & Cecilia Bossa. (2011) Mechanisms of Chemical Carcinogenicity and Mutagenicity: A Review with Implications for Predictive Toxicology. Chemical Reviews 111:4, pages 2507-2536.
Crossref
Amal Saad-HusseinHanaa Hamdy, Hisham M Aziz & Heba Mahdy-Abdallah. (2010) Thyroid functions in paints production workers and the mechanism of oxidative-antioxidants status. Toxicology and Industrial Health 27:3, pages 257-263.
Crossref
Jeremy N. Myers, Perumalla V. Rekhadevi & Aramandla Ramesh. (2011) Comparative Evaluation of Different Cell Lysis and Extraction Methods for Studying Benzo(a)pyrene Metabolism in HT-29 Colon Cancer Cell Cultures. Cellular Physiology and Biochemistry 28:2, pages 209-218.
Crossref
Suse Broyde, Lihua Wang, Yuqin Cai, Lei Jia, Robert Shapiro, Dinshaw J. Patel & Nicholas E. Geacintov. 2011. Chemical Carcinogenesis. Chemical Carcinogenesis 181 207 .
Trevor M. Penning. 2011. Chemical Carcinogenesis. Chemical Carcinogenesis 135 158 .
Ronald G. Harvey. 2011. Chemical Carcinogenesis. Chemical Carcinogenesis 1 26 .
Joost H. M. van Delft, Karen Mathijs, Yvonne C. M. Staal, Marcel H. M. van Herwijnen, Karen J. J. Brauers, André Boorsma & Jos C. S. Kleinjans. (2010) Time Series Analysis of Benzo[A]Pyrene-Induced Transcriptome Changes Suggests That a Network of Transcription Factors Regulates the Effects on Functional Gene Sets. Toxicological Sciences 117:2, pages 381-392.
Crossref
George Sigounas, Jonathan W. Hairr, Charles D. Cooke, Jennifer R. Owen, Adam S. Asch, Douglas A. Weidner & John E. Wiley. (2010) Role of benzo[α]pyrene in generation of clustered DNA damage in human breast tissue. Free Radical Biology and Medicine 49:1, pages 77-87.
Crossref
Stephen Nesnow, Garret Nelson, William T. Padgett, Michael H. George, Tanya Moore, Leon C. King, Linda D. Adams & Jeffrey A. Ross. (2010) Lack of contribution of covalent benzo[a]pyrene-7,8-quinone–DNA adducts in benzo[a]pyrene-induced mouse lung tumorigenesis. Chemico-Biological Interactions 186:2, pages 157-165.
Crossref
Trevor M. Penning. 2010. The Chemical Biology of DNA Damage. The Chemical Biology of DNA Damage 131 155 .
Suse Broyde, Lihua Wang, Dinshaw J. Patel & Nicholas E. Geacintov. 2010. The Chemical Biology of DNA Damage. The Chemical Biology of DNA Damage 331 352 .
Qian Li, Fredine T. Lauer, Ke Jian Liu, Laurie G. Hudson & Scott W. Burchiel. (2010) Low-dose synergistic immunosuppression of T-dependent antibody responses by polycyclic aromatic hydrocarbons and arsenic in C57BL/6J murine spleen cells. Toxicology and Applied Pharmacology 245:3, pages 344-351.
Crossref
Ertuğrul Keskin, Yavuz Yardım & Zühre Şentürk. (2010) Voltammetry of Benzo[a]pyrene in Aqueous and Nonaqueous Media: Adsorptive Stripping Voltammetric Determination at Pencil Graphite Electrode. Electroanalysis 22:11, pages 1191-1199.
Crossref
Stefanie Lubitz, Wolfgang Schober, Gudrun Pusch, Renate Effner, Norman Klopp, Heidrun Behrendt & Jeroen T. M. Buters. (2009) Polycyclic aromatic hydrocarbons from diesel emissions exert proallergic effects in birch pollen allergic individuals through enhanced mediator release from basophils. Environmental Toxicology 25:2, pages 188-197.
Crossref
Katerina Hanzalova, Pavel RossnerJr.Jr. & Radim J. Sram. (2010) Oxidative damage induced by carcinogenic polycyclic aromatic hydrocarbons and organic extracts from urban air particulate matter. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 696:2, pages 114-121.
Crossref
Bo Hang. (2010) Formation and Repair of Tobacco Carcinogen-Derived Bulky DNA Adducts. Journal of Nucleic Acids 2010, pages 1-29.
Crossref
A. Luch & W.M. Baird. 2010. Comprehensive Toxicology. Comprehensive Toxicology 85 123 .
L.A. Peterson, A.M. Urban & S.S. Hecht. 2010. Comprehensive Toxicology. Comprehensive Toxicology 351 377 .
Kerry Donny-Clark & Suse Broyde. (2009) Influence of local sequence context on damaged base conformation in human DNA polymerase ι: molecular dynamics studies of nucleotide incorporation opposite a benzo[a]pyrene-derived adenine lesion. Nucleic Acids Research 37:21, pages 7095-7109.
Crossref
Christopher J. MacDonald, Robert Y.S. Cheng, David D. Roberts, David A. Wink & Grace Chao Yeh. (2009) Modulation of Carcinogen Metabolism by Nitric Oxide-Aspirin 2 Is Associated with Suppression of DNA Damage and DNA Adduct Formation. Journal of Biological Chemistry 284:33, pages 22099-22107.
Crossref
Tomi Nath Das. (2009) Monomer and Dimer Radical Cations of Benzene, Toluene, and Naphthalene. The Journal of Physical Chemistry A 113:23, pages 6489-6493.
Crossref
Pingna Xu, Lida Oum, Yuan-Cho Lee, Nicholas E. Geacintov & Suse Broyde. (2009) Visualizing Sequence-Governed Nucleotide Selectivities and Mutagenic Consequences through a Replicative Cycle: Processing of a Bulky Carcinogen N 2 -dG Lesion in a Y-Family DNA Polymerase . Biochemistry 48:22, pages 4677-4690.
Crossref
Daiwang Xu, Trevor M. Penning, Ian A. Blair & Ronald G. Harvey. (2008) Synthesis of Phenol and Quinone Metabolites of Benzo[ a ]pyrene, a Carcinogenic Component of Tobacco Smoke Implicated in Lung Cancer . The Journal of Organic Chemistry 74:2, pages 597-604.
Crossref
Richard A. Manderville. 2009. 177 218 .
Jong‐Heum Park & Trevor M. Penning. 2008. Process‐Induced Food Toxicants. Process‐Induced Food Toxicants 243 282 .
A. Valavanidis, Th. Vlachogianni, S. Triantafillaki, M. Dassenakis, F. Androutsos & M. Scoullos. (2008) Polycyclic aromatic hydrocarbons in surface seawater and in indigenous mussels (Mytilus galloprovincialis) from coastal areas of the Saronikos Gulf (Greece). Estuarine, Coastal and Shelf Science 79:4, pages 733-739.
Crossref
Gregory M. Sandala, David M. Smith & Leo Radom. (2008) The Carbon-Skeleton Rearrangement in Tropane Alkaloid Biosynthesis. Journal of the American Chemical Society 130:32, pages 10684-10690.
Crossref
S. A. Leavitt, M. H. George, T. Moore & J. A. Ross. (2008) Mutations induced by benzo[a]pyrene and dibenzo[a,l]pyrene in lacI transgenic B6C3F1 mouse lung result from stable DNA adducts. Mutagenesis 23:6, pages 445-450.
Crossref
. (2008) Polycyclic Aromatic Hydrocarbons in Food - Scientific Opinion of the Panel on Contaminants in the Food Chain. EFSA Journal 6:8, pages 724.
Crossref
Chongzhao Ran, Daiwang Xu, Qing Dai, Trevor M. Penning, Ian A. Blair & Ronald G. Harvey. (2008) Synthesis of 13C2-benzo[a]pyrene and its 7,8-dihydrodiol and 7,8-dione implicated as carcinogenic metabolites. Tetrahedron Letters 49:29-30, pages 4531-4533.
Crossref
Jong-Heum Park, Dipti Mangal, Kirk A. Tacka, Amy M. Quinn, Ronald G. Harvey, Ian A. Blair & Trevor M. Penning. (2008) Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans -dihydrodiol activation in human lung A549 cells . Proceedings of the National Academy of Sciences 105:19, pages 6846-6851.
Crossref
Amy M. Quinn & Trevor M. Penning. (2008) Comparisons of (±)-Benzo[ a ]pyrene- trans -7,8-Dihydrodiol Activation by Human Cytochrome P450 and Aldo−Keto Reductase Enzymes: Effect of Redox State and Expression Levels . Chemical Research in Toxicology 21:5, pages 1086-1094.
Crossref
Luqing Pan, Jingjing Miao, Jing Wang & Jing Liu. (2008) AHH activity, tissue dose and DNA damage in different tissues of the scallop Chlamys farreri exposed to benzo[a]pyrene. Environmental Pollution 153:1, pages 192-198.
Crossref
Daiwang Xu, Yazhen Duan, Ian A. Blair, Trevor M. Penning & Ronald G. Harvey. (2008) Synthesis of Dibenzo[ def,p ]chrysene, Its Active Metabolites, and Their 13 C -Labeled Analogues . Organic Letters 10:6, pages 1059-1062.
Crossref
Chongzhao Ran, Qing Dai, Qian Ruan, Trevor M. Penning, Ian A. Blair & Ronald G. Harvey. (2008) Strategies for Synthesis of Adducts of o -Quinone Metabolites of Carcinogenic Polycyclic Aromatic Hydrocarbons with 2‘-Deoxyribonucleosides . The Journal of Organic Chemistry 73:3, pages 992-1003.
Crossref
Vipul K. Singh, D.K. Patel, Jyoti, S. Ram, N. Mathur & M.K.J. Siddiqui. (2008) Blood levels of polycyclic aromatic hydrocarbons in children and their association with oxidative stress indices: An Indian perspective. Clinical Biochemistry 41:3, pages 152-161.
Crossref
Vipul K. Singh, Devendra K. Patel, S. Ram, N. Mathur, M. K. J. Siddiqui & Jai Raj Behari. (2007) Blood Levels of Polycyclic Aromatic Hydrocarbons in Children of Lucknow, India. Archives of Environmental Contamination and Toxicology 54:2, pages 348-354.
Crossref
Dhrubajyoti Chakravarti, Divya Venugopal, Paula C. Mailander, Jane L. Meza, Sheila Higginbotham, Ercole L. Cavalieri & Eleanor G. Rogan. (2008) The role of polycyclic aromatic hydrocarbon–DNA adducts in inducing mutations in mouse skin. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 649:1-2, pages 161-178.
Crossref
Adil Matni, Leila Boubekeur, Philippe Grosshans, Nicolas Mézailles, Gérald Bernardinelli, Pascal Le Floch & Michel Geoffroy. (2007) ESR/DFT study of bis-iminophosphorane cation radicals. Magnetic Resonance in Chemistry 45:12, pages 1011-1017.
Crossref
Mary E. Kushman, Sandra L. Kabler, Sarfaraz Ahmad, Johannes Doehmer, Charles S. Morrow & Alan J. Townsend. (2007) Cytotoxicity and mutagenicity of dibenzo[a,l]pyrene and (±)-dibenzo[a,l]pyrene-11,12-dihydrodiol in V79MZ cells co-expressing either hCYP1A1 or hCYP1B1 together with human glutathione-S-transferase A1. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 624:1-2, pages 80-87.
Crossref
Hao Jiang, Stacy L. Gelhaus, Dipti Mangal, Ronald G. Harvey, Ian A. Blair & Trevor M. Penning. (2007) Metabolism of Benzo[ a ]pyrene in Human Bronchoalveolar H358 Cells Using Liquid Chromatography–Mass Spectrometry . Chemical Research in Toxicology 20:9, pages 1331-1341.
Crossref
Pingna Xu, Lida Oum, Lorena S. Beese, Nicholas E. Geacintov & Suse Broyde. (2007) Following an environmental carcinogen N2-dG adduct through replication: elucidating blockage and bypass in a high-fidelity DNA polymerase. Nucleic Acids Research 35:13, pages 4275-4288.
Crossref
Elise Champeil, Padmanava Pradhan & Mahesh K. Lakshman. (2007) Palladium-Catalyzed Synthesis of Nucleoside Adducts from Bay- and Fjord-Region Diol Epoxides. The Journal of Organic Chemistry 72:14, pages 5035-5045.
Crossref
Qing Dai, Daiwang Xu, Keunpoong Lim & Ronald G. Harvey. (2007) Efficient Syntheses of C 8 -Aryl Adducts of Adenine and Guanine Formed by Reaction of Radical Cation Metabolites of Carcinogenic Polycyclic Aromatic Hydrocarbons with DNA . The Journal of Organic Chemistry 72:13, pages 4856-4863.
Crossref
Jørn A. Holme, Morgane Gorria, Volker M. Arlt, Steinar Øvrebø, Anita Solhaug, Xavier Tekpli, Nina E. Landvik, Laurence Huc, Olivier Fardel & Dominique Lagadic-Gossmann. (2007) Different mechanisms involved in apoptosis following exposure to benzo[a]pyrene in F258 and Hepa1c1c7 cells. Chemico-Biological Interactions 167:1, pages 41-55.
Crossref
M. Cecilia Caino, Jose L. Oliva, Hao Jiang, Trevor M. Penning & Marcelo G. Kazanietz. (2007) Benzo[ a ]pyrene-7,8-dihydrodiol Promotes Checkpoint Activation and G 2 /M Arrest in Human Bronchoalveolar Carcinoma H358 Cells . Molecular Pharmacology 71:3, pages 744-750.
Crossref
Xiaoke Hu, Yi Zhang, Xueheng Zhao & Huey‐Min Hwang. (2007) Biodegradation of benzo[ a ]pyrene with immobilized laccase: Genotoxicity of the products in HaCat and A3 cells . Environmental and Molecular Mutagenesis 48:2, pages 106-113.
Crossref
Yi JinTrevor M. Penning. (2007) Aldo-Keto Reductases and Bioactivation/Detoxication. Annual Review of Pharmacology and Toxicology 47:1, pages 263-292.
Crossref
Lauren A. Courter, Tamara Musafia-Jeknic, Kay Fischer, Robert Bildfell, Jack Giovanini, Cliff Pereira & William M. Baird. (2007) Urban Dust Particulate Matter Alters PAH-Induced Carcinogenesis by Inhibition of CYP1A1 and CYP1B1. Toxicological Sciences 95:1, pages 63-73.
Crossref
Hyun Mee Lee, Youn-Hee Chae, Cheol Kwon & Seog K. Kim. (2007) Conformations of adducts formed between the genotoxic benzo[a]pyrene-7,8-dione and nucleosides studied by density functional theory. Biophysical Chemistry 125:1, pages 151-158.
Crossref
Narayanan Balu, William T. Padgett, Garret B. Nelson, Guy R. Lambert, Jeffrey A. Ross & Stephen Nesnow. (2006) Benzo[a]pyrene-7,8-quinone-3′-mononucleotide adduct standards for 32P postlabeling analyses: Detection of benzo[a]pyrene-7,8-quinone–calf thymus DNA adducts. Analytical Biochemistry 355:2, pages 213-223.
Crossref
Qian Ruan, Hye-Young H. Kim, Hao Jiang, Trevor M. Penning, Ronald G. Harvey & Ian A. Blair. (2006) Quantification of benzo[a]pyrene diol epoxide DNA-adducts by stable isotope dilution liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry 20:8, pages 1369-1380.
Crossref
Yvonne C.M. Staal, Marcel H.M. van Herwijnen, Frederik J. van Schooten & Joost H.M. van Delft. (2006) Modulation of gene expression and DNA adduct formation in HepG2 cells by polycyclic aromatic hydrocarbons with different carcinogenic potencies. Carcinogenesis 27:3, pages 646-655.
Crossref
Kwan-Jae Jung, Matthew A. Wallig & Keith W. Singletary. (2006) Purple grape juice inhibits 7,12-dimethylbenz[a]anthracene (DMBA)-induced rat mammary tumorigenesis and in vivo DMBA-DNA adduct formation. Cancer Letters 233:2, pages 279-288.
Crossref
Jeffrey Ross. 2005. Molecular Carcinogenesis and the Molecular Biology of Human Cancer. Molecular Carcinogenesis and the Molecular Biology of Human Cancer 79 101 .
David Warshawsky & Weiling Xue. 2005. Molecular Carcinogenesis and the Molecular Biology of Human Cancer. Molecular Carcinogenesis and the Molecular Biology of Human Cancer 45 77 .
Weiling Xue & David Warshawsky. (2005) Metabolic activation of polycyclic and heterocyclic aromatic hydrocarbons and DNA damage: A review. Toxicology and Applied Pharmacology 206:1, pages 73-93.
Crossref
Chongzhao Ran, Qing Dai & Ronald G. Harvey. (2005) N 6 -Arylation of 2‘-Deoxyadenosine via Copper-Catalyzed Direct Coupling with Aryl Halides . The Journal of Organic Chemistry 70:9, pages 3724-3726.
Crossref
Qing Dai, Chongzhao Ran & Ronald G. Harvey. (2005) Synthesis of Adducts of o -Quinone Metabolites of Carcinogenic Polycyclic Aromatic Hydrocarbons with 2‘-Deoxyribonucleosides . Organic Letters 7:6, pages 999-1002.
Crossref
B. Marczynski, R. Preuss, T. Mensing, J. Angerer, A. Seidel, A. El Mourabit, M. Wilhelm & T. Brüning. (2005) Genotoxic risk assessment in white blood cells of occupationally exposed workers before and after alteration of the polycyclic aromatic hydrocarbon (PAH) profile in the production material: comparison with PAH air and urinary metabolite levels. International Archives of Occupational and Environmental Health 78:2, pages 97-108.
Crossref
Paul R. Ortiz de Montellano & James J. De Voss. 2005. Cytochrome P450. Cytochrome P450 183 245 .
Steven G. Carmella, Menglan Chen, Haruhiko Yagi, Donald M. Jerina & Stephen S. Hecht. (2004) Analysis of Phenanthrols in Human Urine by Gas Chromatography-Mass Spectrometry: Potential Use in Carcinogen Metabolite Phenotyping. Cancer Epidemiology, Biomarkers & Prevention 13:12, pages 2167-2174.
Crossref
Sébastien Garry, Fabrice Nesslany, ElMoukhtar Aliouat, Jean-Marie Haguenoer & Daniel Marzin. (2004) Hematite (Fe2O3) acts by oxydative stress and potentiates benzo[a]pyrene genotoxicity. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 563:2, pages 117-129.
Crossref
Aramandla Ramesh, Stormy A. Walker, Darryl B. Hood, Maria D. Guillén, Klaus Schneider & Eric H. Weyand. (2016) Bioavailability and Risk Assessment of Orally Ingested Polycyclic Aromatic Hydrocarbons. International Journal of Toxicology 23:5, pages 301-333.
Crossref
Deh-Wei Tang, Kuo-Wei Chang, Chin-Wen Chi & Tsung-Yun Liu. (2004) Hydroxychavicol modulates benzo[a]pyrene-induced genotoxicity through induction of dihydrodiol dehydrogenase. Toxicology Letters 152:3, pages 235-243.
Crossref
Andreas F. Lehner, Jamie Horn & James W. Flesher. (2004) Formation of radical cations in a model for the metabolism of aromatic hydrocarbons. Biochemical and Biophysical Research Communications 322:3, pages 1018-1023.
Crossref
Nevenka Bihari & Maja Fafanđel. (2004) Interspecies differences in DNA single strand breaks caused by benzo(a)pyrene and marine environment. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 552:1-2, pages 209-217.
Crossref
Karl L Platt, Hans P Dienes, Manuela Tommasone & Andreas Luch. (2004) Tumor formation in the neonatal mouse bioassay indicates that the potent carcinogen dibenzo[def,p]chrysene (dibenzo[a,l]pyrene) is activated in vivo via its trans-11,12-dihydrodiol. Chemico-Biological Interactions 148:1-2, pages 27-36.
Crossref
Ronald G. Harvey, Qing Dai, Chongzhao Ran & Trevor M. Penning. (2004) Synthesis of the o -Quinones and Other Oxidized Metabolites of Polycyclic Aromatic Hydrocarbons Implicated in Carcinogenesis . The Journal of Organic Chemistry 69:6, pages 2024-2032.
Crossref
Trevor M. Penning. 2004. Quinones and Quinone Enzymes, Part A. Quinones and Quinone Enzymes, Part A 31 67 .
Sébastien Garry, Fabrice Nesslany, ElMoukhtar Aliouat, Jean-Marie Haguenoer & Daniel Marzin. (2003) Hematite (Fe2O3) enhances benzo[a]pyrene genotoxicity in endotracheally treated rat, as determined by Comet Assay. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 538:1-2, pages 19-29.
Crossref
C. Gravato & M.A. Santos. (2003) Genotoxicity biomarkers’ association with B(a)P biotransformation in Dicentrarchus labrax L.. Ecotoxicology and Environmental Safety 55:3, pages 352-358.
Crossref
Rao Saladi, Lisa Austin, Dayuan Gao, Yuhun Lu, Robert Phelps, Mark Lebwohl & Huachen Wei. (2007) The Combination of Benzo[a]pyrene and Ultraviolet A Causes an In Vivo Time-related Accumulation of DNA Damage in Mouse Skin ¶. Photochemistry and Photobiology 77:4, pages 413-419.
Crossref
Bhagavatula Moorthy, Kimberly P. Miller, Weiwu Jiang, E. Spencer Williams, Sudha R. Kondraganti & Kenneth S. Ramos. (2003) Role of Cytochrome P4501B1 in Benzo[ a ]pyrene Bioactivation to DNA-Binding Metabolites in Mouse Vascular Smooth Muscle Cells: Evidence from 32 P-Postlabeling for Formation of 3-Hydroxybenzo[ a ]pyrene and Benzo[ a ]pyrene-3,6-quinone as Major Proximate Genotoxic Intermediates . Journal of Pharmacology and Experimental Therapeutics 305:1, pages 394-401.
Crossref
David Lai & Yin-Tak Woo. 2003. Quantitative Structure-Activity Relationship (QSAR) Models of Mutagens and Carcinogens. Quantitative Structure-Activity Relationship (QSAR) Models of Mutagens and Carcinogens.
Rao Saladi, Lisa Austin, Dayuan Gao, Yuhun Lu, Robert Phelps, Mark Lebwohl & Huachen Wei. (2003) The Combination of Benzo[a]pyrene and Ultraviolet A Causes an In Vivo Time-related Accumulation of DNA Damage in Mouse Skin¶. Photochemistry and Photobiology 77:4, pages 413.
Crossref
Guillaume Garçon, Pierre Gosset, Benoît Maunit, Anne Casset, Marie-Hélène Hannothiaux, Jean-François Müller & Pirouz Shirali. (2003) Mécanismes cellulaires de la synergie d'action de polluants atmosphériques (Fe203 ET HPA) dans l'apparition du cancer broncho-pulmonaire. Revue Française des Laboratoires 2003:349, pages 59-68.
Crossref
Kai H LiaoIvan D DobrevJames E DennisonJrJrMelvin E AndersenBrad ReisfeldKenneth F ReardonJulie A CampainWei WeiMichael T KleinRichard J QuannRaymond S H Yang. (2002) Application of biologically based computer modeling to simple or complex mixtures.. Environmental Health Perspectives 110:suppl 6, pages 957-963.
Crossref

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