Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 26, 1996 - Issue 1
110
Views
112
CrossRef citations to date
0
Altmetric
Research Article

Effects of canthaxanthin, astaxanthin, lycopene and lutein on liver xenobiotic-metabolizing enzymes in the rat

, , , , &
Pages 49-63 | Published online: 17 Nov 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (13)

Xinyu Duan, Cundong Xie, David R. A. Hill, Colin J. Barrow, Frank R. Dunshea, Gregory J. O. Martin & Hafiz A.R. Suleria. (2023) Bioaccessibility, Bioavailability and Bioactivities of Carotenoids in Microalgae: A Review. Food Reviews International 0:0, pages 1-30.
Read now
Nima Montazeri-Najafabady, Mohammad Hossein Dabbaghmanesh, Nazanin Chatrabnous & Mohammad Reza Arabnezhad. (2020) The Effects of Astaxanthin on Proliferation and Differentiation of MG-63 Osteosarcoma Cells via Aryl Hydrocarbon Receptor (AhR) Pathway: A Comparison with AhR Endogenous Ligand. Nutrition and Cancer 72:8, pages 1400-1410.
Read now
Hasina Begum, Fatimah MD. Yusoff, Sanjoy Banerjee, Helena Khatoon & Mohamed Shariff. (2016) Availability and Utilization of Pigments from Microalgae. Critical Reviews in Food Science and Nutrition 56:13, pages 2209-2222.
Read now
H. Stutz, N. Bresgen & P. M. Eckl. (2015) Analytical tools for the analysis of β-carotene and its degradation products. Free Radical Research 49:5, pages 650-680.
Read now
Hitoshi Ashida, Shin Nishiumi & Itsuko Fukuda. (2008) An update on the dietary ligands of the AhR. Expert Opinion on Drug Metabolism & Toxicology 4:11, pages 1429-1447.
Read now
MistyR. Saracino & JohannaW. Lampe. (2007) Phytochemical Regulation of UDP-Glucuronosyltransferases: Implications for Cancer Prevention. Nutrition and Cancer 59:2, pages 121-141.
Read now
Michael Murray. (2007) Role of signalling systems in the effects of dietary factors on the expression of mammalian CYPs. Expert Opinion on Drug Metabolism & Toxicology 3:2, pages 185-196.
Read now
Harumi Jyonouchi, Sining Sun, Koji Iijima & Myron D. Gross. (2000) Antitumor Activity of Astaxanthin and Its Mode of Action. Nutrition and Cancer 36:1, pages 59-65.
Read now
Pierre Astorg, Sandra Gradelet, Raymond Bergès & Marc Suschetet. (1997) Dietary lycopene decreases the initiation of liver preneoplastic foci by diethylnitrosamine in the rat. Nutrition and Cancer 29:1, pages 60-68.
Read now
Pierre Astorg, Sandra Gradelet, Joel Leclerc & Marie‐Hélène Siess. (1997) Effects of provitamin a or non‐provitamin a carotenoids on liver xenobiotic‐metabolizing enzymes in mice. Nutrition and Cancer 27:3, pages 245-249.
Read now
S. Gradelet, J. Leclerc, M-H. Siess & P. O. Astorg. (1996) β-Apo-8′-carotenal, but not β-carotene, is a strong inducer of liver cytochromes P4501A1 and 1A2 in rat. Xenobiotica 26:9, pages 909-919.
Read now

Articles from other publishers (99)

Ayodeji Ojo Oteyola, Raffaele Pilla, Folasade Adesola Ola-Oladimeji, Omotayo Fagbuaro, Daiana Silva de Avila, Chibuisi Gideon Alimba, Erika Cristina Jorge & Fernanda R. C. L. de Almeida. 2023. Natural Products as Cancer Therapeutics. Natural Products as Cancer Therapeutics 230 253 .
Mengya Wang, Hui Ding, Shaoxuan Wu, Mingyi Wang, Jiayi Ma, Jie Xiao, Zhenmin Bao, Bo Wang & Jingjie Hu. (2023) Comparative transcriptome analysis provides new insights into the protective effect of astaxanthin on the liver of leopard coral grouper (Plectropomus leopardus). Aquaculture 565, pages 739118.
Crossref
Carlos Alonso‐Alvarez, Pedro Andrade, Alejandro Cantarero, Judith Morales & Miguel Carneiro. (2022) Relocation to avoid costs: A hypothesis on red carotenoid‐based signals based on recent CYP2J19 gene expression data . BioEssays 44:12.
Crossref
Li Xu, Yiyun Liu, Yangsheng Chen, Ruihong Zhu, Siqi Li, Songyan Zhang, Jian Zhang, Heidi Qunhui Xie & Bin Zhao. (2022) Emodin inhibits U87 glioblastoma cells migration by activating aryl hydrocarbon receptor (AhR) signaling pathway. Ecotoxicology and Environmental Safety 234, pages 113357.
Crossref
Trine Ytrestøyl, Sergey Afanasyev, Bente Ruyter, Bjarne Hatlen, Tone-Kari Østbye & Aleksei Krasnov. (2021) Transcriptome and functional responses to absence of astaxanthin in Atlantic salmon fed low marine diets. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics 39, pages 100841.
Crossref
P. Madan Kumar, J. Naveen, R. Janani & V. Baskaran. 2021. Global Perspectives on Astaxanthin. Global Perspectives on Astaxanthin 569 591 .
M. Barbosa, P. Valentão & P.B. Andrade. 2020. Encyclopedia of Marine Biotechnology. Encyclopedia of Marine Biotechnology 1391 1426 .
Tingting Niu, Jiawei Zhou, Feng Wang, Rongrong Xuan, Juanjuan Chen, Wei Wu & Haimin Chen. (2020) Safety assessment of astaxanthin from Haematococcus pluvialis: Acute toxicity, genotoxicity, distribution and repeat-dose toxicity studies in gestation mice. Regulatory Toxicology and Pharmacology 115, pages 104695.
Crossref
P. Marić, M. Ahel, O. Babić, J. Simeunović & T. Smital. (2020) Ecotoxicological profiling of selected cyanobacterial strains using multi-endpoint effect-directed analysis. Ecotoxicology 29:5, pages 535-550.
Crossref
Pietro Antonuccio, Antonio Micali, Domenico Puzzolo, Carmelo Romeo, Giovanna Vermiglio, Violetta Squadrito, Jose Freni, Giovanni Pallio, Vincenzo Trichilo, Maria Righi, Natasha Irrera, Domenica Altavilla, Francesco Squadrito, Herbert R. Marini & Letteria Minutoli. (2020) Nutraceutical Effects of Lycopene in Experimental Varicocele: An “In Vivo” Model to Study Male Infertility. Nutrients 12:5, pages 1536.
Crossref
Fernando Pagels, Daniel Salvaterra, Helena Melo Amaro & Ana Catarina Guedes. 2020. Handbook of Microalgae-Based Processes and Products. Handbook of Microalgae-Based Processes and Products 465 492 .
Chang-Hwei ChenChang-Hwei Chen. 2020. Xenobiotic Metabolic Enzymes: Bioactivation and Antioxidant Defense. Xenobiotic Metabolic Enzymes: Bioactivation and Antioxidant Defense 205 219 .
Timothy E. Hoffman, Evan R. Acerbo, Kasimir F. Carranza, Vincenzo S. Gilberto, Lyle E. Wallis & William H. Hanneman. (2018) Ultrasensitivity dynamics of diverse aryl hydrocarbon receptor modulators in a hepatoma cell line. Archives of Toxicology 93:3, pages 635-647.
Crossref
Tuba Esatbeyoglu & Gerald Rimbach. (2017) Canthaxanthin: From molecule to function. Molecular Nutrition & Food Research 61:6, pages 1600469.
Crossref
Iain A. Murray & Gary H. Perdew. (2017) Ligand activation of the Ah receptor contributes to gastrointestinal homeostasis. Current Opinion in Toxicology 2, pages 15-23.
Crossref
Yu Zheng, Jee Min, Doyun Kim, Jung Park, Sung-Wook Choi, Eun Lee, Kun Na & Soo Bae. (2016) In Vitro Inhibition of Human UDP-Glucuronosyl-Transferase (UGT) Isoforms by Astaxanthin, β-Cryptoxanthin, Canthaxanthin, Lutein, and Zeaxanthin: Prediction of in Vivo Dietary Supplement-Drug Interactions. Molecules 21:8, pages 1052.
Crossref
James A. Edwards, Phillip Bellion, Paul Beilstein, Robert Rümbeli & Joseph Schierle. (2016) Review of genotoxicity and rat carcinogenicity investigations with astaxanthin. Regulatory Toxicology and Pharmacology 75, pages 5-19.
Crossref
James A. Edwards. (2016) Zeaxanthin: Review of Toxicological Data and Acceptable Daily Intake. Journal of Ophthalmology 2016, pages 1-15.
Crossref
Aicha Yefsah-Idres, Yasmina Benazzoug, Amel Otman, Alizée Latour, Sandrine Middendorp & Nathalie Janel. (2016) Hepatoprotective effects of lycopene on liver enzymes involved in methionine and xenobiotic metabolism in hyperhomocysteinemic rats. Food & Function 7:6, pages 2862-2869.
Crossref
Romilly E. Hodges & Deanna M. Minich. (2015) Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical Application. Journal of Nutrition and Metabolism 2015, pages 1-23.
Crossref
Chitralekha Nag Dasgupta. 2015. Algal Biorefinery: An Integrated Approach. Algal Biorefinery: An Integrated Approach 253 276 .
. (2014) Scientific Opinion on the safety of astaxanthin-rich ingredients (AstaREAL A1010 and AstaREAL L10) as novel food ingredients. EFSA Journal 12:7, pages 3757.
Crossref
Hemant Kumar, In-Su Kim, Sandeep Vasant More, Byung-Wook Kim & Dong-Kug Choi. (2014) Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases. Nat. Prod. Rep. 31:1, pages 109-139.
Crossref
Charles Y.F. Young, K.V. Donkena, H.-Q. Yuan, M.-L. He & J.-Y. Zhang. 2014. Recent Advances in Medicinal Chemistry. Recent Advances in Medicinal Chemistry 246 271 .
Yu Fen Zheng, Soo Hyeon Bae, Min Jo Kwon, Jung Bae Park, Hye Duck Choi, Wan Gyoon Shin & Soo Kyung Bae. (2013) Inhibitory effects of astaxanthin, β-cryptoxanthin, canthaxanthin, lutein, and zeaxanthin on cytochrome P450 enzyme activities. Food and Chemical Toxicology 59, pages 78-85.
Crossref
Míriam Cristina Sakuragui Matuo, Rafael Teruiti de Oliveira Takamoto, Irene Satiko Kikuchi & Terezinha de Jesus Andreoli Pinto. (2013) Effect of bixin and norbixin on the expression of cytochrome P450 in HepG2 cell line. Cell Biology International 37:8, pages 843-848.
Crossref
Rachel E. Kopec & Steven J. Schwartz. 2013. Carotenoid Cleavage Products. Carotenoid Cleavage Products 31 41 .
Paola Palozza, Assunta Catalano & Marta Zaccardi. 2013. Cancer Chemoprevention and Treatment by Diet Therapy. Cancer Chemoprevention and Treatment by Diet Therapy 141 167 .
Fang Hao, Neelu Yadav & Dhyan Chandra. 2013. Mitochondria as Targets for Phytochemicals in Cancer Prevention and Therapy. Mitochondria as Targets for Phytochemicals in Cancer Prevention and Therapy 219 243 .
Yoav Sharoni, Karin Linnewiel-Hermoni, Gabriel Zango, Marina Khanin, Hagar Salman, Anna Veprik, Michael Danilenko & Joseph Levy. (2012) The role of lycopene and its derivatives in the regulation of transcription systems: implications for cancer prevention. The American Journal of Clinical Nutrition 96:5, pages 1173S-1178S.
Crossref
Xiang-Dong Wang. (2012) Lycopene metabolism and its biological significance. The American Journal of Clinical Nutrition 96:5, pages 1214S-1222S.
Crossref
Takuji Tanaka, Masahito Shnimizu & Hisataka Moriwaki. (2012) Cancer Chemoprevention by Carotenoids. Molecules 17:3, pages 3202-3242.
Crossref
Marumi Ohno, Wageh Sobhy Darwish, Yoshinori Ikenaka, Wataru Miki, Shoichi Fujita & Mayumi Ishizuka. (2012) Astaxanthin rich crude extract of Haematococcus pluvialis induces cytochrome P450 1A1 mRNA by activating aryl hydrocarbon receptor in rat hepatoma H4IIE cells. Food Chemistry 130:2, pages 356-361.
Crossref
Marumi Ohno, Yoshinori Ikenaka & Mayumi Ishizuka. (2012) All-trans retinoic acid inhibits the recruitment of ARNT to DNA, resulting in the decrease of CYP1A1 mRNA expression in HepG2 cells. Biochemical and Biophysical Research Communications 417:1, pages 484-489.
Crossref
Dalal Asker, Tarek S. Awad, Teruhiko Beppu & Kenji Ueda. 2012. Microbial Carotenoids from Bacteria and Microalgae. Microbial Carotenoids from Bacteria and Microalgae 61 97 .
Chang-Hwei ChenChang-Hwei Chen. 2012. Activation and Detoxification Enzymes. Activation and Detoxification Enzymes 91 102 .
Kazuaki TAKAHASHI, Tetsuya TAKIMOTO, Kan SATO & Yukio AKIBA. (2011) Effect of dietary supplementation of astaxanthin from Phaffia rhodozyma on lipopolysaccharide-induced early inflammatory responses in male broiler chickens (Gallus gallus) fed a corn-enriched diet. Animal Science Journal 82:6, pages 753-758.
Crossref
Jason Matthews. 2011. Hormone-Disruptive Chemical Contaminants in Food. Hormone-Disruptive Chemical Contaminants in Food 115 135 .
Marumi Ohno, Wageh S. Darwish, Yoshinori Ikenaka, Wataru Miki & Mayumi Ishizuka. (2011) Astaxanthin can alter CYP1A-dependent activities via two different mechanisms: Induction of protein expression and inhibition of NADPH P450 reductase dependent electron transfer. Food and Chemical Toxicology 49:6, pages 1285-1291.
Crossref
Joseph Levy, Shlomo Walfisch, Andrea Atzmon, Keren Hirsch, Marina Khanin, Karin Linnewiel, Yael Morag, Hagar Salman, Anna Veprik, Michael Danilenko & Yoav Sharoni. 2011. Vegetables, Whole Grains, and Their Derivatives in Cancer Prevention. Vegetables, Whole Grains, and Their Derivatives in Cancer Prevention 47 66 .
Tim Hofer, Tonje Engevik Eriksen, Espen Hansen, Ingrid Varmedal, Ida-Johanne Jensen, Jeanette Hammer-Andersen & Ragnar Ludvig Olsen. 2011. Studies on Experimental Models. Studies on Experimental Models 637 657 .
G. Goswami, S. Chaudhuri & D. Dutta. (2010) The present perspective of astaxanthin with reference to biosynthesis and pharmacological importance. World Journal of Microbiology and Biotechnology 26:11, pages 1925-1939.
Crossref
. (2010) Scientific Opinion on the re-evaluation of lutein (E 161b) as a food additive. EFSA Journal 8:7, pages 1678.
Crossref
Eun Hee Han, Hyung Gyun Kim, Ji Hye Im, Tae Cheon Jeong & Hye Gwang Jeong. (2009) Up-regulation of CYP1A1 by rutaecarpine is dependent on aryl hydrocarbon receptor and calcium. Toxicology 266:1-3, pages 38-47.
Crossref
Paola Palozza, Cristiana Torelli, Alma Boninsegna, Rossella Simone, Assunta Catalano, Maria Cristina Mele & Nevio Picci. (2009) Growth-inhibitory effects of the astaxanthin-rich alga Haematococcus pluvialis in human colon cancer cells. Cancer Letters 283:1, pages 108-117.
Crossref
John W. ErdmanJr.Jr., Nikki A. Ford & Brian L. Lindshield. (2009) Are the health attributes of lycopene related to its antioxidant function?. Archives of Biochemistry and Biophysics 483:2, pages 229-235.
Crossref
Xiang-Dong Wang. 2009. Carotenoids. Carotenoids 383 408 .
Jonathan R Mein, Fuzhi Lian & Xiang-Dong Wang. (2008) Biological activity of lycopene metabolites: implications for cancer prevention. Nutrition Reviews 66:12, pages 667-683.
Crossref
Rangaswamy Lakshminarayana, Gorusupudi Aruna, Ravi Kumar Sangeetha, Narayan Bhaskar, Sounder Divakar & Vallikannan Baskaran. (2008) Possible degradation/biotransformation of lutein in vitro and in vivo: isolation and structural elucidation of lutein metabolites by HPLC and LC-MS (atmospheric pressure chemical ionization). Free Radical Biology and Medicine 45:7, pages 982-993.
Crossref
John S. Stewart, Åke Lignell, Annette Pettersson, Elisabeth Elfving & M.G. Soni. (2008) Safety assessment of astaxanthin-rich microalgae biomass: Acute and subchronic toxicity studies in rats. Food and Chemical Toxicology 46:9, pages 3030-3036.
Crossref
Kevin T Connor, Mark A Harris, Melanie R Edwards, Robert A Budinsky, George C Clark, Andrew C Chu, Brent L Finley & J Craig Rowlands. (2007) AH receptor agonist activity in human blood measured with a cell-based bioassay: Evidence for naturally occurring AH receptor ligands in vivo. Journal of Exposure Science & Environmental Epidemiology 18:4, pages 369-380.
Crossref
. (2008) Use of Lycopene as a food colour - Scientific Opinion of the Panel on Food additives, Flavourings, Processing Aids and Materials in Contact with Food. EFSA Journal 6:4, pages 674.
Crossref
T. Ytrestøyl & B. Bjerkeng. (2007) Intraperitoneal and dietary administration of astaxanthin in rainbow trout (Oncorhynchus mykiss) — Plasma uptake and tissue distribution of geometrical E/Z isomers. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 147:2, pages 250-259.
Crossref
J. Boateng, M. Verghese, L. Shackelford, L.T. Walker, J. Khatiwada, S. Ogutu, D.S. Williams, J. Jones, M. Guyton, D. Asiamah, F. Henderson, L. Grant, M. DeBruce, A. Johnson, S. Washington & C.B. Chawan. (2007) Selected fruits reduce azoxymethane (AOM)-induced aberrant crypt foci (ACF) in Fisher 344 male rats. Food and Chemical Toxicology 45:5, pages 725-732.
Crossref
Dietrich Petri & Anne-Katrine Lundebye. (2007) Tissue distribution of astaxanthin in rats following exposure to graded levels in the feed. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 145:2, pages 202-209.
Crossref
T. Ytrestøyl & B. Bjerkeng. (2007) Dose response in uptake and deposition of intraperitoneally administered astaxanthin in Atlantic salmon (Salmo salar L.) and Atlantic cod (Gadus morhua L.). Aquaculture 263:1-4, pages 179-191.
Crossref
M. Abraham Kuriakose & Rajeev Sharan. (2006) Oral Cancer Prevention. Oral and Maxillofacial Surgery Clinics of North America 18:4, pages 493-511.
Crossref
Swadesh K. Das, Takashi Hashimoto, Masaki Baba, Hoyoku Nishino, Akitoshi Komoto & Kazuki Kanazawa. (2006) Japanese Kelp (Kombu) Extract Suppressed the Formation of Aberrant Crypt Foci in Azoxymethane Challenged Mouse Colon. Journal of Clinical Biochemistry and Nutrition 38:2, pages 119-125.
Crossref
G.I. Page & S.J. Davies. (2006) Tissue astaxanthin and canthaxanthin distribution in rainbow trout (Oncorhynchus mykiss) and Atlantic salmon (Salmo salar). Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 143:1, pages 125-132.
Crossref
Samuel F. Lockwood & Garrett J. Gross. (2006) Disodium Disuccinate Astaxanthin (CardaxTM): Antioxidant and Antiinflammatory Cardioprotection. Cardiovascular Drug Reviews 23:3, pages 199-216.
Crossref
Laurent Dufossé, Patrick Galaup, Anina Yaron, Shoshana Malis Arad, Philippe Blanc, Kotamballi N. Chidambara Murthy & Gokare A. Ravishankar. (2005) Microorganisms and microalgae as sources of pigments for food use: a scientific oddity or an industrial reality?. Trends in Food Science & Technology 16:9, pages 389-406.
Crossref
. (2005) Opinion of the Scientific Panel on Dietetic products, nutrition and allergies [NDA] related to an application on the use of a-tocopherol-containing oil suspension of lycopene from Blakeslea trispora as a novel food ingredient. EFSA Journal 3:6, pages 212.
Crossref
Vaidhyanathan Bhuvaneswari, Suresh K. Abraham & Siddavaram Nagini. (2005) Combinatorial antigenotoxic and anticarcinogenic effects of tomato and garlic through modulation of xenobiotic-metabolizing enzymes during hamster buccal pouch carcinogenesis. Nutrition 21:6, pages 726-731.
Crossref
Katrine Borgå, Hans Wolkers, Janneche U. Skaare, Haakon Hop, Derek C.G. Muir & Geir W. Gabrielsen. (2005) Bioaccumulation of PCBs in Arctic seabirds: influence of dietary exposure and congener biotransformation. Environmental Pollution 134:3, pages 397-409.
Crossref
K.N. Chidambara Murthy, A. Vanitha, J. Rajesha, M. Mahadeva Swamy, P.R. Sowmya & Gokare A. Ravishankar. (2005) In vivo antioxidant activity of carotenoids from Dunaliella salina — a green microalga. Life Sciences 76:12, pages 1381-1390.
Crossref
Anat Ben-Dor, Michael Steiner, Larisa Gheber, Michael Danilenko, Noga Dubi, Karin Linnewiel, Anat Zick, Yoav Sharoni & Joseph Levy. (2005) Carotenoids activate the antioxidant response element transcription system. Molecular Cancer Therapeutics 4:1, pages 177-186.
Crossref
John Dore. 2004. Phytopharmaceuticals in Cancer Chemoprevention. Phytopharmaceuticals in Cancer Chemoprevention.
Yoav Sharoni, Michael Danilenko, Noga Dubi, Anat Ben-Dor & Joseph Levy. (2004) Carotenoids and transcription. Archives of Biochemistry and Biophysics 430:1, pages 89-96.
Crossref
Tom O'Connor & Nora O'Brien. 2004. Carotenoids in Health and Disease. Carotenoids in Health and Disease 197 208 .
Wilhelm Stahl, Michael Danilenko, Yoav Sharoni & Joseph Levy. 2004. Carotenoids in Health and Disease. Carotenoids in Health and Disease 165 196 .
Harold Furr & Richard Clark. 2004. Carotenoids in Health and Disease. Carotenoids in Health and Disease 229 278 .
H Tapiero, D.M Townsend & K.D Tew. (2004) The role of carotenoids in the prevention of human pathologies. Biomedicine & Pharmacotherapy 58:2, pages 100-110.
Crossref
Susan Zaripheh, Mary Ann Lila, John W. ErdmanJrJr & Thomas W.-M. Boileau. (2003) [14C]-Lycopene and [14C]-Labeled Polar Products Are Differentially Distributed in Tissues of F344 Rats Prefed Lycopene. The Journal of Nutrition 133:12, pages 4189-4195.
Crossref
Yoav Sharoni, Riad Agbaria, Hadar Amir, Anat Ben-Dor, Irene Bobilev, Noga Doubi, Yudit Giat, Keren Hirsh, Gaby Izumchenko, Marina Khanin, Elena Kirilov, Rita Krimer, Amit Nahum, Michael Steiner, Yossi Walfisch, Shlomo Walfisch, Gabi Zango, Michael Danilenko & Joseph Levy. (2003) Modulation of transcriptional activity by antioxidant carotenoids. Molecular Aspects of Medicine 24:6, pages 371-384.
Crossref
G.I Page & S.J Davies. (2003) Hepatic carotenoid uptake in rainbow trout (Oncorhynchus mykiss) using an isolated organ perfusion model. Aquaculture 225:1-4, pages 405-419.
Crossref
C. Kelly, C. Jewell & N.M. O’Brien. (2003) The effect of dietary supplementation with the citrus limonoids, limonin and nomilin on xenobiotic-metabolizing enzymes in the liver and small intestine of the rat. Nutrition Research 23:5, pages 681-690.
Crossref
Michael S. DenisonScott R. Nagy. (2003) Activation of the Aryl Hydrocarbon Receptor by Structurally Diverse Exogenous and Endogenous Chemicals. Annual Review of Pharmacology and Toxicology 43:1, pages 309-334.
Crossref
A.C.A.X. De-Oliveira, I.B. Silva, D.A. Manhães-Rocha & F.J.R. Paumgartten. (2003) Induction of liver monooxygenases by annatto and bixin in female rats. Brazilian Journal of Medical and Biological Research 36:1, pages 113-118.
Crossref
S. Southon & R. Faulks. 2003. Phytochemical Functional Foods. Phytochemical Functional Foods 107 127 .
G.I Page & S.J Davies. (2002) Astaxanthin and canthaxanthin do not induce liver or kidney xenobiotic-metabolizing enzymes in rainbow trout (Oncorhynchus mykiss Walbaum). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 133:3, pages 443-451.
Crossref
Michael S Denison, Alessandro Pandini, Scott R Nagy, Enoch P Baldwin & Laura Bonati. (2002) Ligand binding and activation of the Ah receptor. Chemico-Biological Interactions 141:1-2, pages 3-24.
Crossref
W. Stahl, N. Ale-Agha & M.C. Polidori. (2002) Non-Antioxidant Properties of Carotenoids. Biological Chemistry 383:3-4, pages 553-558.
Crossref
Patrizia Riso & Marisa Porrini. 2000. Vegetables, Fruits, and Herbs in Health Promotion. Vegetables, Fruits, and Herbs in Health Promotion.
Johanna W. Lampe, Irena B. King, Sue Li, Margaret T. Grate, Karen V. Barale, Chu Chen, Ziding Feng & John D. Potter. (2000) Brassica vegetables increase and apiaceous vegetables decrease cytochrome P450 1A2 activity in humans: changes in caffeine metabolite ratios in response to controlled vegetable diets. Carcinogenesis 21:6, pages 1157-1162.
Crossref
Garry G. Duthie, Susan J. Duthie & Janet A. M. Kyle. (2007) Plant polyphenols in cancer and heart disease: implications as nutritional antioxidants. Nutrition Research Reviews 13:1, pages 79-106.
Crossref
Vibeke Breinholt, Søren T Lauridsen, Bahram Daneshvar & Jette Jakobsen. (2000) Dose-response effects of lycopene on selected drug-metabolizing and antioxidant enzymes in the rat. Cancer Letters 154:2, pages 201-210.
Crossref
William A. Pryor, Wilhelm Stahl & Cheryl L. Rock. (2009) Beta Carotene: From Biochemistry to Clinical Trials. Nutrition Reviews 58:2, pages 39-53.
Crossref
Hideki Arimochi, Keiko Kataoka, Tomomi Kuwahara, Haruyuki Nakayama, Norihiko Misawa & Yoshinari Ohnishi. (1999) Effects of β-Glucuronidase-Deficient and Lycopene-Producing Escherichia coli Strains on Formation of Azoxymethane-Induced Aberrant Crypt Foci in the Rat Colon. Biochemical and Biophysical Research Communications 262:2, pages 322-327.
Crossref
J Wolkers, I.C Burkow, M Monshouwer, C Lydersen, S Dahle & R.F Witkamp. (1999) Cytochrome P450-mediated enzyme activities and polychlorinated biphenyl accumulation in harp seal (Phoca groenlandica). Marine Environmental Research 48:1, pages 59-72.
Crossref
Christopher Jewell & Nora M. O'Brien. (2007) Effect of dietary supplementation with carotenoids on xenobiotic metabolizing enzymes in the liver, lung, kidney and small intestine of the rat. British Journal of Nutrition 81:3, pages 235-242.
Crossref
D. Phelan, G.M. Winter, W.J. Rogers, J.C. Lam & M.S. Denison. (1998) Activation of the Ah Receptor Signal Transduction Pathway by Bilirubin and Biliverdin. Archives of Biochemistry and Biophysics 357:1, pages 155-163.
Crossref
Patric Amcoff, Hans Börjeson, Leif Norrgren & Maija Pesonen. (1998) Cytochrome P4501A-activity in rainbow trout (Oncorhynchus mykiss) hepatocytes after exposure to PCB#126 and astaxanthin: In vitro and in vivo studies. Marine Environmental Research 46:1-5, pages 1-5.
Crossref
Steven K. Clinton. (2009) Lycopene: Chemistry, Biology, and Implications for Human Health and Disease. Nutrition Reviews 56:2, pages 35-51.
Crossref
D.L Madhavi, J Bomser, M.A.L Smith & K Singletary. (1998) Isolation of bioactive constituents from Vaccinium myrtillus (bilberry) fruits and cell cultures. Plant Science 131:1, pages 95-103.
Crossref
Mark Harker & Joseph Hirschberg. 1998. Photosynthesis: Molecular Biology of Energy Capture. Photosynthesis: Molecular Biology of Energy Capture 244 263 .
Pierre Astorg. (1997) Food carotenoids and cancer prevention: An overview of current research. Trends in Food Science & Technology 8:12, pages 406-413.
Crossref
Pascal Grolier, Christelle Duszka, Patrick Borel, Marie-Cécile Alexandre-Gouabau & Véronique Azais-Braesco. (1997) In Vitroandin VivoInhibition of β-Carotene Dioxygenase Activity by Canthaxanthin in Rat Intestine. Archives of Biochemistry and Biophysics 348:2, pages 233-238.
Crossref
Sandra Gradelet, Pierre Astorg, Thierry Pineau, Marie-Chantal Canivenc, Marie-Hélène Siess, Joël Leclerc & Pierre Lesca. (1997) Ah receptor-dependent CYP1A induction by two carotenoids, canthaxanthin and β-apo-8″-carotenal, with no affinity for the TCDD binding site. Biochemical Pharmacology 54:2, pages 307-315.
Crossref
Sandra Gradelet, Pierre Astorg, Anne-Marie Le Bon, Raymond Bergès & Marc Suschetet. (1997) Modulation of aflatoxin B1 carcinogenicity, genotoxicity and metabolism in rat liver by dietary carotenoids: evidence for a protective effect of CYP1A inducers. Cancer Letters 114:1-2, pages 221-223.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.