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Xenobiotica
the fate of foreign compounds in biological systems
Volume 26, 1996 - Issue 2
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Research Article

Glucuronidation of diflunisal in liver and kidney microsomes of rat and man

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Pages 123-131 | Received 07 Aug 1995, Published online: 22 Sep 2008

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Read on this site (6)

Hiroyuki Ikuta, Hiroaki Shimada, Kenjiro Sakamoto, Rena Nakamura, Atsushi Kawase & Masahiro Iwaki. (2022) Species differences in liver microsomal hydrolysis of acyl glucuronide in humans and rats. Xenobiotica 52:7, pages 653-660.
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Takashi Koyanagi, Koji Yano, Soonih Kim, Norie Murayama, Hiroshi Yamazaki & Ikumi Tamai. (2019) In vivo hepatic clearance of lipophilic drugs predicted by in vitro uptake data into cryopreserved hepatocytes suspended in sera of rats, guinea pigs, monkeys and humans. Xenobiotica 49:8, pages 887-894.
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Kathleen M. Knights & John O. Miners. (2010) Renal UDP-glucuronosyltransferases and the glucuronidation of xenobiotics and endogenous mediators. Drug Metabolism Reviews 42:1, pages 63-73.
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Michael B. Fisher, Mary F. Paine, Timothy J. Strelevitz & Steven A. Wrighton. (2001) The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism*†. Drug Metabolism Reviews 33:3-4, pages 273-297.
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Articles from other publishers (14)

John O. Miners, Thomas M. Polasek, Julie-Ann Hulin, Andrew Rowland & Robyn Meech. (2023) Drug-drug interactions that alter the exposure of glucuronidated drugs: Scope, UDP-glucuronosyltransferase (UGT) enzyme selectivity, mechanisms (inhibition and induction), and clinical significance. Pharmacology & Therapeutics 248, pages 108459.
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Hiroaki Shimada, Hiroyuki Ikuta, Keisuke Kumazawa, Manato Nomi, Mayumi Shiojiri, Atsushi Kawase & Masahiro Iwaki. (2022) Relationship between the risk of idiosyncratic drug toxicity and formation and degradation profiles of acyl-glucuronide metabolites of nonsteroidal anti-inflammatory drugs in rat liver microsomes. European Journal of Pharmaceutical Sciences 174, pages 106193.
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Jin Zhou & John O. Miners. 2014. Enzyme Kinetics in Drug Metabolism. Enzyme Kinetics in Drug Metabolism 203 228 .
Alexander V. LyubimovShalu Jhajra, Ninad Ramesh Varkhede, Deepak Suresh Ahire, Bukke Vidyasagar Naik, Bhagwat Prasad, Jyoti Paliwal & Saranjit Singh. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 99 .
Alexander V. LyubimovRobert S. Foti, Dan A. Rock, Larry C. Wienkers & Jan L. Wahlstrom. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 68 .
Alexander V. LyubimovRobert S. Foti & Michael B. Fisher. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 71 .
Lauren Oleson & Michael H Court. (2008) Effect of the β-glucuronidase inhibitor saccharolactone on glucuronidation by human tissue microsomes and recombinant UDP-glucuronosyltransferases. Journal of Pharmacy and Pharmacology 60:9, pages 1175-1182.
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Kathleen M. Knights, Leanne K. Winner, David J. Elliot, Kushari Bowalgaha & John O. Miners. (2009) Aldosterone glucuronidation by human liver and kidney microsomes and recombinant UDP‐glucuronosyltransferases: Inhibition by NSAIDs. British Journal of Clinical Pharmacology 68:3, pages 402-412.
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Chuanhui Yu, Joseph K. Ritter, Richard J. Krieg, Bhaskar Rege, Thomas H. Karnes & Mohamadi A. Sarkar. (2006) EFFECT OF CHRONIC RENAL INSUFFICIENCY ON HEPATIC AND RENAL UDP-GLUCURONYLTRANSFERASES IN RATS. Drug Metabolism and Disposition 34:4, pages 621-627.
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Maria Shipkova, Victor William Armstrong, Michael Oellerich & Eberhard Wieland. (2003) Acyl Glucuronide Drug Metabolites: Toxicological and Analytical Implications. Therapeutic Drug Monitoring 25:1, pages 1-16.
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Sam Boase & John O. Miners. (2002) In vitro–in vivo correlations for drugs eliminated by glucuronidation: Investigations with the model substrate zidovudine . British Journal of Clinical Pharmacology 54:5, pages 493-503.
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Khalid M. Alkharfy & Reginald F. Frye. (2001) High-performance liquid chromatographic assay for acetaminophen glucuronide in human liver microsomes. Journal of Chromatography B: Biomedical Sciences and Applications 753:2, pages 303-308.
Crossref
Brian Burchell. 1999. Handbook of Drug Metabolism. Handbook of Drug Metabolism 153 173 .
Frank Bohnenstengel, Heyo K. Kroemer & Bernhard Sperker. (1999) In vitro cleavage of paracetamol glucuronide by human liver and kidney β-glucuronidase: determination of paracetamol by capillary electrophoresis. Journal of Chromatography B: Biomedical Sciences and Applications 721:2, pages 295-299.
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