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Xenobiotica
the fate of foreign compounds in biological systems
Volume 26, 1996 - Issue 2
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Research Article

Metabolism of barnidipine hydrochloride, a potent calcium antagonist, in rat and dog

T. Teramura Drug Metabolism Department, Clinical Pharmacology Research Laboratories, Yamanouchi Pharmaceutical Co. Ltd, 1-8 Azusawa 1-chome, Itabashi-ku, Tokyo, 174, Japan
,
T. Tokunaga Structure Analysis Department, Molecular Chemistry Research Laboratories, Yamanouchi Pharmaceutical Co. Ltd, 21, Miyukigaoka, Ibaraki, 305, Japan
,
H. Matsumoto Structure Analysis Department, Molecular Chemistry Research Laboratories, Yamanouchi Pharmaceutical Co. Ltd, 21, Miyukigaoka, Ibaraki, 305, Japan
,
T. Watanabe Drug Metabolism Department, Clinical Pharmacology Research Laboratories, Yamanouchi Pharmaceutical Co. Ltd, 1-8 Azusawa 1-chome, Itabashi-ku, Tokyo, 174, Japan
&
S. Higuchi Drug Metabolism Department, Clinical Pharmacology Research Laboratories, Yamanouchi Pharmaceutical Co. Ltd, 1-8 Azusawa 1-chome, Itabashi-ku, Tokyo, 174, Japan
Pages 177-187 | Received 13 Jul 1995, Published online: 22 Sep 2008

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T. TERAMURA*Y. FUKUNAGA, E. J. VAN HOOGDALEM, T. WATANABE & S. HIGUCHI. (1997) Examination of metabolic pathways and identification of human liver cytochrome P450 isozymes responsible for the metabolism of barnidipine, a calcium channel blocker. Xenobiotica 27:9, pages 885-900.
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Articles from other publishers (5)

Lu Wang, Lijun Xie, Sufeng Zhou, Yuanyuan Wang, Juan Chen, Yanli Zhou, Yun Liu, Hongwen Zhang, Mingxue Tao, Ning Ou & Feng Shao. (2018) A Randomized, Open‐Label, Crossover Phase 1 Study to Evaluate the Effects of Food on the Pharmacokinetics of a Single Oral Dose of a 15‐mg Tylerdipine Tablet in Healthy Chinese Male Volunteers. Clinical Pharmacology in Drug Development 8:1, pages 126-132.
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Ruina Gao. 2014. Handbook of Metabolic Pathways of Xenobiotics. Handbook of Metabolic Pathways of Xenobiotics 1 3 .
Ruina Gao. 2014. Handbook of Metabolic Pathways of Xenobiotics. Handbook of Metabolic Pathways of Xenobiotics 1 4 .
M. Stefek, V. Faberova, S. Musil & I. Kakalik. (2001) Urinary excretion of the 1,4-dihydropyridine calcium antagonist VULM 993 and its metabolites in the rat. European Journal of Drug Metabolism and Pharmacokinetics 26:4, pages 221-226.
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Toshiharu Sakai, Toshio Teramura, Hideaki Okamiya & Osamu Inagaki. (2007) A Review on Barnidipine: A Novel Calcium Antagonist. Cardiovascular Drug Reviews 15:4, pages 273-290.
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