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Xenobiotica
the fate of foreign compounds in biological systems
Volume 26, 1996 - Issue 3
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Research Article

Identification and antimicrobial activity of urinary metabolites of a rifamycin derivative in dog

K. Hosoe Takasago Research Laboratories, Kaneka Corp., 1–8 Miyamae Takasago-cho, Takasago-shi, Hyogo, 676, Japan
,
T. Mae Takasago Research Laboratories, Kaneka Corp., 1–8 Miyamae Takasago-cho, Takasago-shi, Hyogo, 676, Japan
,
K. Yamashita Takasago Research Laboratories, Kaneka Corp., 1–8 Miyamae Takasago-cho, Takasago-shi, Hyogo, 676, Japan
,
K. Fujii Takasago Research Laboratories, Kaneka Corp., 1–8 Miyamae Takasago-cho, Takasago-shi, Hyogo, 676, Japan
,
T. Yamane Fine Chemical Research Laboratories, Kaneka Corp., 1–8 Miyamae Takasago-cho, Takasago-shi, Hyogo, 676, Japan
,
T. Hidaka Takasago Research Laboratories, Kaneka Corp., 1–8 Miyamae Takasago-cho, Takasago-shi, Hyogo, 676, Japan
&
T. Ohashi Takasago Research Laboratories, Kaneka Corp., 1–8 Miyamae Takasago-cho, Takasago-shi, Hyogo, 676, Japan
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Pages 321-332 | Received 05 Aug 1995, Published online: 22 Sep 2008

Citations (6)

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Read on this site (2)

David M Rothstein, Arthur D Hartman, Michael H Cynamon & Barry I Eisenstein. (2003) Development potential of rifalazil. Expert Opinion on Investigational Drugs 12:2, pages 255-271.
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T. Mae, K. Hosoe, K. Fujii, K. Yamashita, T. Yamane, T. Hidaka & T. Ohashi. (1996) In vitro metabolism of a rifamycin derivative by animal and human liver microsomes, whole blood and expressed human CYP3A isoform. Xenobiotica 26:8, pages 793-802.
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Articles from other publishers (4)

Vadim V. Mozhaev, Lyudmila V. Mozhaeva, Peter C. Michels & Yuri L. Khmelnitsky. (2008) Extractive Biotransformation for Production of Metabolites of Poorly Soluble Compounds: Synthesis of 32-Hydroxy-rifalazil. Drug Metabolism and Disposition 36:10, pages 1998-2004.
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Marita Larsson & Feng Han. (2007) Determination of rifalazil in dog plasma by liquid–liquid extraction and LC–MS/MS: Quality assessment by incurred sample analysis. Journal of Pharmaceutical and Biomedical Analysis 45:4, pages 616-624.
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David M. Rothstein, John van Duzer, Andrew Sternlicht & Steven C. Gilman. (2007) Rifalazil and Other Benzoxazinorifamycins in the Treatment of Chlamydia‐Based Persistent Infections. Archiv der Pharmazie 340:10, pages 517-529.
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K HosoeT MaeE KonishiK FujiiK YamashitaT YamaneT HidakaT Ohashi. (1996) Pharmacokinetics of KRM-1648, a new benzoxazinorifamycin, in rats and dogs. Antimicrobial Agents and Chemotherapy 40:12, pages 2749-2755.
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