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Xenobiotica
the fate of foreign compounds in biological systems
Volume 26, 1996 - Issue 3
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Research Article

Metabolism of tamsulosin in rat and dog

Y. Soeishi Drug Metabolism Department, Clinical Pharmacology Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd, 1–8 Azusawa 1-chome, Itabashi-ku, Tokyo, 174, Japan
,
H. Matsushima Drug Metabolism Department, Clinical Pharmacology Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd, 1–8 Azusawa 1-chome, Itabashi-ku, Tokyo, 174, Japan
,
Y. Teraya Drug Metabolism Department, Clinical Pharmacology Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd, 1–8 Azusawa 1-chome, Itabashi-ku, Tokyo, 174, Japan
,
T. Watanabe Drug Metabolism Department, Clinical Pharmacology Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd, 1–8 Azusawa 1-chome, Itabashi-ku, Tokyo, 174, Japan
,
S. Higuchi Drug Metabolism Department, Clinical Pharmacology Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd, 1–8 Azusawa 1-chome, Itabashi-ku, Tokyo, 174, Japan
&
H. Kaniwa Structure Analysis Department, Molecular Chemistry Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd, Miyukigaoka 21, Tsukuba-shi, Ibaraki, 305, Japan
Pages 355-365 | Received 20 Sep 1995, Published online: 22 Sep 2008

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H. KAMIMURA, S. OISHIOE, H. MATSUSHIMA, T. WATANABE, S. HIGUCHI, M. HALL, S. G. WOOD & L. F. CHASSEAUD. (1998) Identification of cytochrome P450 isozymes involved in metabolism of the α1-adrenoceptor blocker tamsulosin in human liver microsomes. Xenobiotica 28:10, pages 909-922.
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Y. Soeishi, H. Matsushima, T. Watanabe, S. Higuchi, K. Cornelissen & J. Ward. (1996) Absorption, metabolism and excretion of tamsulosin hydrochloride in man. Xenobiotica 26:6, pages 637-645.
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Articles from other publishers (12)

Huafang Li, Jiansong Yang, Hongxin Zhao, Michael J. Fossler & Chunrong Wang. (2015) Effect of tamsulosin on the pharmacokinetics of dutasteride in Chinese male healthy volunteers. Clinical Pharmacology in Drug Development 4:6, pages 427-433.
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Abdul Naveed Shaik. 2014. Handbook of Metabolic Pathways of Xenobiotics. Handbook of Metabolic Pathways of Xenobiotics 1 3 .
Gabriela Franco-Salinas, Jean J.M.C.H. de la Rosette & Martin C. Michel. (2010) Pharmacokinetics and Pharmacodynamics of Tamsulosin in its Modified-Release and Oral Controlled Absorption System Formulations. Clinical Pharmacokinetics 49:3, pages 177-188.
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HE Kang, SK Bae, M Yoo, DC Lee, YG Kim & MG Lee. (2009) Interaction between udenafil and tamsulosin in rats: non-competitive inhibition of tamsulosin metabolism by udenafil via hepatic CYP3A1/2. British Journal of Pharmacology 156:6, pages 1009-1018.
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L E Randle, J G Sathish, N R Kitteringham, I Macdonald, D P Williams & B K Park. (2008) α 1 -Adrenoceptor antagonists prevent paracetamol-induced hepatotoxicity in mice . British Journal of Pharmacology 153:4, pages 820-830.
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John A. Davies & Martin C. Michel. 2007. xPharm: The Comprehensive Pharmacology Reference. xPharm: The Comprehensive Pharmacology Reference 1 7 .
W. N. Wu, L. A. Mckown & G. H. Kuo. (2006) Hepatic metabolism of two α-1A-adrenergic receptor antagonists, phthalimide-phenylpiperazine analogs (RWJ-69205 and RWJ-69471), in the rat, dog and human. European Journal of Drug Metabolism and Pharmacokinetics 31:4, pages 271-276.
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Hiroshi Matsushima, Takashi Watanabe & Saburo Higuchi. (2000) Effect of α1‐Acid Glycoprotein on the Pharmacokinetics of Tamsulosin in Rats Treated with Turpentine Oil. Journal of Pharmaceutical Sciences 89:4, pages 490-498.
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Alaa F Badawi. (1998) O6-Methylguanine and O6-methylguanine-dna methyltransferase activity in tissues of BDF-1 mice treated with antiparasitic drugs. Toxicology Letters 94:3, pages 199-208.
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Katsunari Taguchi, Rafael F. Schäfers & Martin C. Michel. (2002) Radioreceptor assay analysis of tamsulosin and terazosin pharmacokinetics. British Journal of Clinical Pharmacology 45:1, pages 49-55.
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Ewoud J. Van Hoogdalem, Yoshiaki Soeishi, Hiroshi Matsushima & Saburo Higuchi. (1997) Disposition of the Selective α1A-Adrenoceptor Antagonist Tamsulosin in Humans: Comparison with Data from Interspecies Scaling. Journal of Pharmaceutical Sciences 86:10, pages 1156-1161.
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Hiroshi Matsushima, Ken-ichi Takanuki, Hidetaka Kamimura, Takashi Watanabe & Saburo Higuchi. (1997) Highly sensitive method for the determination of tamsulosin hydrochloride in human plasma dialysate, plasma and urine by high-performance liquid chromatography–electrospray tandem mass spectrometry. Journal of Chromatography B: Biomedical Sciences and Applications 695:2, pages 317-327.
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