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Xenobiotica
the fate of foreign compounds in biological systems
Volume 26, 1996 - Issue 5
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Research Article

Pharmacokinetics of ethylene glycol. III. Plasma disposition and metabolic fate after single increasing intravenous, peroral, or percutaneous doses in the male Sprague-Dawley rat

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Pages 515-539 | Received 13 May 1995, Published online: 22 Sep 2008

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R. Gomes, R. G. Liteplo & M. E. Meek. (2001) ETHYLENE GLYCOL: HAZARD CHARACTERIZATION AND EXPOSURE–RESPONSE ANALYSIS. Journal of Environmental Science and Health, Part C 19:1, pages 189-217.
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Articles from other publishers (14)

Szabina A. Stice & Edward W. Carney. 2022. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology 803 814 .
Jeff Fowles, Marcy Banton, Joanna Klapacz & Hua Shen. (2017) A toxicological review of the ethylene glycol series: Commonalities and differences in toxicity and modes of action. Toxicology Letters 278, pages 66-83.
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Edward W. Carney & Szabina A. Stice. 2017. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology 797 809 .
Edward W. Carney, Belen Tornesi, Ashley B. Liberacki, Daniel A. Markham, Karl K. Weitz, Teressa M. Luders, Kristine G. Studniski, John C. Blessing, Richard A. Gies & Richard A. Corley. (2011) The Impact of Dose Rate on Ethylene Glycol Developmental Toxicity and Pharmacokinetics in Pregnant CD Rats. Toxicological Sciences 119:1, pages 178-188.
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Edward W. Carney. 2011. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology 607 615 .
Swapna Upadhyay, Joern Carstens, Dominik Klein, Thomas H. Faller, Stephan Halbach, Werner Kirchinger, Winfried Kessler, György A. Csanády & Johannes G. Filser. (2008) Inhalation and epidermal exposure of volunteers to ethylene glycol: Kinetics of absorption, urinary excretion, and metabolism to glycolate and oxalate. Toxicology Letters 178:2, pages 131-141.
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R. A. Corley, M. J. Bartels, E. W. Carney, K. K. Weitz, J. J. Soelberg, R. A. Gies & K. D. Thrall. (2005) Development of a Physiologically Based Pharmacokinetic Model for Ethylene Glycol and Its Metabolite, Glycolic Acid, in Rats and Humans. Toxicological Sciences 85:1, pages 476-490.
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. (2004) NTP-CERHR Expert Panel report on the reproductive and developmental toxicity of ethylene glycol. Reproductive Toxicology 18:4, pages 457-532.
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Nina Vasavada, Craig Williams & Richard N. Hellman. (2012) Ethylene Glycol Intoxication: Case Report and Pharmacokinetic Perspectives. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 23:12, pages 1652-1658.
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Patrick Poulin & Frank‐Peter Theil. (2002) Prediction of Pharmacokinetics Prior to In Vivo Studies. 1. Mechanism‐Based Prediction of Volume of Distribution. Journal of Pharmaceutical Sciences 91:1, pages 129-156.
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S Klug, H.-J Merker & R Jäckh. (2001) Effects of ethylene glycol and metabolites on in vitro development of rat embryos during organogenesis. Toxicology in Vitro 15:6, pages 635-642.
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L. H. Pottenger, E. W. Carney & M. J. Bartels. (2001) Dose-Dependent Nonlinear Pharmacokinetics of Ethylene Glycol Metabolites in Pregnant (GD 10) and Nonpregnant Sprague-Dawley Rats following Oral Administration of Ethylene Glycol. Toxicological Sciences 62:1, pages 10-19.
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L. Schladt, I. Ivens, E. Karbe, C. Rühl-Fehlert & E. Bomhard. (1998) Subacute oral toxicity of tetraethylene glycol and ethylene glycoladministered to Wistar rats. Experimental and Toxicologic Pathology 50:3, pages 257-265.
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J G SarverD WhiteP ErhardtK Bachmann. (1997) Estimating xenobiotic half-lives in humans from rat data: influence of log P.. Environmental Health Perspectives 105:11, pages 1204-1209.
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