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Xenobiotica
the fate of foreign compounds in biological systems
Volume 26, 1996 - Issue 6
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Research Article

Sex differences in the metabolism of (+)-S-145, a novel thromboxane A2 receptor antagonist in rat

Y. Yamaguchi Department of Drug Metabolism and Disposition, Developmental Research Laboratories, Shionogi & Co., Ltd, Toyonaka, Osaka, 561, Japan
,
R. Norikura Department of Drug Metabolism and Disposition, Developmental Research Laboratories, Shionogi & Co., Ltd, Toyonaka, Osaka, 561, Japan
,
M. Nakanishi Department of Drug Metabolism and Disposition, Developmental Research Laboratories, Shionogi & Co., Ltd, Toyonaka, Osaka, 561, Japan
,
A. Touchi Department of Drug Metabolism and Disposition, Developmental Research Laboratories, Shionogi & Co., Ltd, Toyonaka, Osaka, 561, Japan
,
T. Yoshimori Department of Drug Metabolism and Disposition, Developmental Research Laboratories, Shionogi & Co., Ltd, Toyonaka, Osaka, 561, Japan
,
T. Murakami Department of Drug Metabolism and Disposition, Developmental Research Laboratories, Shionogi & Co., Ltd, Toyonaka, Osaka, 561, Japan
,
T. Baba Department of Drug Metabolism and Disposition, Developmental Research Laboratories, Shionogi & Co., Ltd, Toyonaka, Osaka, 561, Japan
,
K. Mizojiri Department of Drug Metabolism and Disposition, Developmental Research Laboratories, Shionogi & Co., Ltd, Toyonaka, Osaka, 561, Japan
&
T. Matsubara Department of Drug Metabolism and Disposition, Developmental Research Laboratories, Shionogi & Co., Ltd, Toyonaka, Osaka, 561, Japan
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Pages 613-626 | Received 30 Nov 1995, Published online: 22 Sep 2008

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Y. Yamaguchi, A. Touchi, T. Baba & T. Matsubara. (2001) Species differences in β-oxidative metabolism of a thromboxane A2-receptor antagonist [(+)-S-145] in rat, dog and monkey. Xenobiotica 31:3, pages 125-133.
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Articles from other publishers (3)

Tohru Mizutare, Seigo Sanoh, Takushi Kanazu, Shigeru Ohta & Yaichiro Kotake. (2022) Improved Predictability of Hepatic Clearance with Optimal pH for Acyl-Glucuronidation in Liver Microsomes. Journal of Pharmaceutical Sciences 111:11, pages 3165-3173.
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Bernard Testa & Stefanie D. Krämer. (2008) The Biochemistry of Drug Metabolism – An Introduction. Chemistry & Biodiversity 5:11, pages 2171-2336.
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Takashi Matsubara. (2002) Safety Evaluation and Drug Development based on Biological Fate of Drugs —Efforts Made to Overcome Drug Interaction in Drug Development—. Drug Metabolism and Pharmacokinetics 17:5, pages 379-394.
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