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Xenobiotica
the fate of foreign compounds in biological systems
Volume 26, 1996 - Issue 7
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Research Article

Molecular modelling of CYP1A subfamily members based on an alignment with CYP102: rationalization of CYP1A substrate specificity in terms of active site amino acid residues

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Pages 723-753 | Received 08 Dec 1996, Published online: 22 Sep 2008

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Fang-Liang Zhang, Xin He, Yi-Ran Zhai, Li-Na He, Si-Chao Zhang, Li-Li Wang, Ai-Hong Yang & Li-Jun An. (2015) Mechanism-based inhibition of CYPs and RMs-induced hepatoxicity by rutaecarpine. Xenobiotica 45:11, pages 978-989.
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Dong Dong, Baojian Wu, Diana Chow & Ming Hu. (2012) Substrate selectivity of drug-metabolizing cytochrome P450s predicted from crystal structures and in silico modeling. Drug Metabolism Reviews 44:2, pages 192-208.
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Li-Ping Yang, Zhi-Wei Zhou, Xiao-Wu Chen, Chun Guang Li, Kevin B. Sneed, Jun Liang & Shu-Feng Zhou. (2012) Computational and in vitro studies on the inhibitory effects of herbal compounds on human cytochrome P450 1A2. Xenobiotica 42:3, pages 238-255.
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Shu-Feng Zhou, Bo Wang, Li-Ping Yang & Jun-Ping Liu. (2010) Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2. Drug Metabolism Reviews 42:2, pages 268-354.
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A. Messina, V. Chirulli, P. G. Gervasi & V. Longo. (2008) Purification, molecular cloning, heterologous expression and characterization of pig CYP1A2. Xenobiotica 38:12, pages 1453-1470.
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GrazynaD. Szklarz & MarkD. Paulsen. (2002) Molecular Modeling of Cytochrome P450 1A1: Enzyme-Substrate Interactions and Substrate Binding Affinities. Journal of Biomolecular Structure and Dynamics 20:2, pages 155-162.
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Slobodan Rendic. (2002) Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metabolism Reviews 34:1-2, pages 83-448.
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D. F. V. Lewis, C. Ioannides & D. V. Parke. (1998) An Improved and Updated Version of the Compact Procedure for the Evaluation of P450-Mediated Chemical Activation. Drug Metabolism Reviews 30:4, pages 709-737.
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