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Xenobiotica
the fate of foreign compounds in biological systems
Volume 26, 1996 - Issue 12
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Research Article

Inhibition of tolbutamide 4-methylhydroxylation by a series of non-steroidal anti-inflammatory drugs in V79-NH cells expressing human cytochrome P4502C10

W. A. Kappers Research Institute of Toxicology, Pharmacology and Toxicology, Utrecht University, Yalelaan 2, PO Box 80.176, NL-3508 TD, Utrecht, the Netherlands
,
E. M. De Groene Department of Veterinary Pharmacy, Pharmacology and Toxicology, Utrecht University, Yalelaan 2, PO Box 80.176, NL-3508 TD, Utrecht, the Netherlands
,
L. A. Kleij Research Institute of Toxicology, Pharmacology and Toxicology, Utrecht University, Yalelaan 2, PO Box 80.176, NL-3508 TD, Utrecht, the Netherlands
,
R. F. Witkamp Department of Veterinary Pharmacy, Pharmacology and Toxicology, Utrecht University, Yalelaan 2, PO Box 80.176, NL-3508 TD, Utrecht, the Netherlands
,
W. M. Zweers-zeilmaker Department of Veterinary Pharmacy, Pharmacology and Toxicology, Utrecht University, Yalelaan 2, PO Box 80.176, NL-3508 TD, Utrecht, the Netherlands
,
V. J. Feron TNO-ITV, Utrechtseweg 48, PO Box 360, NL-3700 AJ, Zeist, the Netherlands
&
G. J. Horbach Research Institute of Toxicology, Pharmacology and Toxicology, Utrecht University, Yalelaan 2, PO Box 80.176, NL-3508 TD, Utrecht, the Netherlands
 show all
Pages 1231-1239 | Received 10 Jun 1996, Published online: 22 Sep 2008

Citations (6)

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Read on this site (1)

Slobodan Rendic & Frederick J. Di Carlo. (1997) Human Cytochrome P450 Enzymes: A Status Report Summarizing Their Reactions, Substrates, Inducers, and Inhibitors. Drug Metabolism Reviews 29:1-2, pages 413-580.
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Articles from other publishers (5)

Franziska Lochmann, Aleksandar Nikolajevic, Valentina Stock, Sarah Kammerer, Monica L Fernández-Quintero, Johannes R Loeffler, Klaus R Liedl, Jakob Troppmair, Chris A Mayhew & Veronika Ruzsanyi. (2023) Establishing a cell-based screening workflow for determining the efficiency of CYP2C9 metabolism: moving towards the use of breath volatiles in personalised medicine. Journal of Breath Research 17:4, pages 046001.
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Wendela A Kappers, François M.M van Och, Els M de Groene & G.Jean Horbach. (2000) Comparison of three different in vitro mutation assays used for the investigation of cytochrome P450-mediated mutagenicity of nitro-polycyclic aromatic hydrocarbons. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 466:2, pages 143-159.
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Per Damkier, Lone L. Hansen & Kim Brøsen. (2001) Effect of diclofenac, disulfiram, itraconazole, grapefruit juice and erythromycin on the pharmacokinetics of quinidine. British Journal of Clinical Pharmacology 48:6, pages 829-838.
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M. Monshouwer, G.A.E. van't Klooster, S.M. Nijmeijer, R.F. Witkamp & A.S.J.P.A.M. van Miert. (1998) Characterization of cytochrome P450 isoenzymes in primary cultures of pig hepatocytes. Toxicology in Vitro 12:6, pages 715-723.
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W.M. Zweers‐ZeilmakerG.J. Horbach & R.F. Witkamp. (2002) Effects of non steroidal anti‐inflammatory drugs and sulfonamides on hepatic cytochrome P4502C activity in vitro in goats and cattle . Journal of Veterinary Pharmacology and Therapeutics 21:2, pages 154-157.
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