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Research Article

Cytotoxicity and genotoxicity of titanium dioxide nanoparticles in UVA-irradiated normal peripheral blood lymphocytes

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Pages 277-284 | Received 08 Jul 2010, Accepted 03 Dec 2010, Published online: 07 Jun 2011

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Niusha Abbasi Gamasaee, Hawzheen A. Muhammad, Elahe Tadayon, Mahsa Ale-Ebrahim, Mirsasan Mirpour, Majid Sharifi, Abbas Salihi, Mudhir Sabir Shekha, Asaad A. B. Alasady, Falah Mohammad Aziz, Keivan Akhtari, Anwarul Hasan & Mojtaba Falahati. (2020) The effects of nickel oxide nanoparticles on structural changes, heme degradation, aggregation of hemoglobin and expression of apoptotic genes in lymphocytes. Journal of Biomolecular Structure and Dynamics 38:12, pages 3676-3686.
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Clayton Wright, Anand Krishnan V. Iyer, Liying Wang, Nianqiang Wu, Juan S. Yakisich, Yon Rojanasakul & Neelam Azad. (2017) Effects of titanium dioxide nanoparticles on human keratinocytes. Drug and Chemical Toxicology 40:1, pages 90-100.
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Masanori Horie, Sakiko Sugino, Haruhisa Kato, Yosuke Tabei, Ayako Nakamura & Yasukazu Yoshida. (2016) Does photocatalytic activity of TiO2 nanoparticles correspond to photo-cytotoxicity? Cellular uptake of TiO2 nanoparticles is important in their photo-cytotoxicity. Toxicology Mechanisms and Methods 26:4, pages 284-294.
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Nana Asare, Nur Duale, Hege H. Slagsvold, Birgitte Lindeman, Ann Karin Olsen, Joanna Gromadzka-Ostrowska, Sylwia Meczynska-Wielgosz, Marcin Kruszewski, Gunnar Brunborg & Christine Instanes. (2016) Genotoxicity and gene expression modulation of silver and titanium dioxide nanoparticles in mice. Nanotoxicology 10:3, pages 312-321.
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Zuzana Magdolenova, Andrew Collins, Ashutosh Kumar, Alok Dhawan, Vicki Stone & Maria Dusinska. (2014) Mechanisms of genotoxicity. A review of in vitro and in vivo studies with engineered nanoparticles. Nanotoxicology 8:3, pages 233-278.
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Kui Liu, Xialu Lin & Jinshun Zhao. (2013) Toxic effects of the interaction of titanium dioxide nanoparticles with chemicals or physical factors. International Journal of Nanomedicine 8, pages 2509-2520.
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Hongmei Chang, Qianqian Wang, Xiaojia Meng, Xinyu Chen, Yaxin Deng, Li Li, Yaqian Yang, Guanling Song & Huaimiao Jia. (2022) Effect of Titanium Dioxide Nanoparticles on Mammalian Cell Cycle In Vitro : A Systematic Review and Meta-Analysis . Chemical Research in Toxicology 35:9, pages 1435-1456.
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In Young Kim, Tae Geol Lee, Vytas Reipa & Min Beom Heo. (2021) Titanium Dioxide Induces Apoptosis under UVA Irradiation via the Generation of Lysosomal Membrane Permeabilization-Dependent Reactive Oxygen Species in HaCat Cells. Nanomaterials 11:8, pages 1943.
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Fanny Knorr, Alexa Patzelt, Martina Claudia Meinke, Anika Vogt, Ulrike Blume-Peytavi, Eckart Rühl & Jürgen Lademann. 2019. Biological Responses to Nanoscale Particles. Biological Responses to Nanoscale Particles 329 339 .
P. Schulte, V. Leso, M. Niang & I. Iavicoli. (2018) Biological monitoring of workers exposed to engineered nanomaterials. Toxicology Letters 298, pages 112-124.
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Seung-Uk Lee, Ji-Eun Lee, Su-Jin Kim & Jong-Soo Lee. (2018) Effects of titanium dioxide nanoparticles on the inhibition of cellular activity in human Tenon’s fibroblasts under UVA exposure. Graefe's Archive for Clinical and Experimental Ophthalmology 256:10, pages 1895-1903.
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Shunbang Yu, Joanna Bohatko-Naismith, Xudong Zhang, Xiaonan Zhou, Pu Wang & He Wang. (2017) Cellular Responses in Titanium Dioxide Nanoparticle Cytotoxicity Studies: Parts of the Map Waiting to be Composed. Journal of Medicinal Chemistry and Toxicology 2:2, pages 62-70.
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Yu. V. Lozovska, L. A. Naleskina, N. Yu. Lukyanova, I. M. Todor & V. F. Chekhun. (2015) Assessment of the geno- and cytotoxic action of colloidal gold nanoparticles on the bone marrow erythroid cell lines and tumors in animals with Ehrlich ascites carcinoma. Cytology and Genetics 49:1, pages 42-48.
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Kimberly S. Butler, Brendan J. Casey, Garret V.M. Garborcauskas, Benita J. Dair & Rosalie K. Elespuru. (2014) Assessment of titanium dioxide nanoparticle effects in bacteria: Association, uptake, mutagenicity, co-mutagenicity and DNA repair inhibition. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 768, pages 14-22.
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Daniele Nogueira, Montserrat Mitjans, Clarice Rolim & M. Vinardell. (2014) Mechanisms Underlying Cytotoxicity Induced by Engineered Nanomaterials: A Review of In Vitro Studies. Nanomaterials 4:2, pages 454-484.
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Ivo Iavicoli, Veruscka Leso, Maurizio Manno & Paul A. Schulte. (2014) Biomarkers of nanomaterial exposure and effect: current status. Journal of Nanoparticle Research 16:3.
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Da Dong Guo, Hong Sheng Bi, Qiu Xin Wu & Dao Guang Wang. (2012) Titanium Dioxide Nanoparticles Induced Cytotoxicity in Rat Retinal Ganglion Cells under Ultraviolet B Irradiation. Key Engineering Materials 531-532, pages 500-503.
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Lanzhou Chen, Lina Zhou, Yongding Liu, Songqiang Deng, Hao Wu & Gaohong Wang. (2012) Toxicological effects of nanometer titanium dioxide (nano-TiO2) on Chlamydomonas reinhardtii. Ecotoxicology and Environmental Safety 84, pages 155-162.
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Jean Cadet, Stéphane Mouret, Jean-Luc Ravanat & Thierry Douki. (2012) Photoinduced Damage to Cellular DNA: Direct and Photosensitized Reactions†. Photochemistry and Photobiology 88:5, pages 1048-1065.
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Alexandra Jaeger, Dieter G. Weiss, Ludwig Jonas & Ralf Kriehuber. (2012) Oxidative stress-induced cytotoxic and genotoxic effects of nano-sized titanium dioxide particles in human HaCaT keratinocytes. Toxicology 296:1-3, pages 27-36.
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Nana Asare, Christine Instanes, Wiggo J. Sandberg, Magne Refsnes, Per Schwarze, Marcin Kruszewski & Gunnar Brunborg. (2012) Cytotoxic and genotoxic effects of silver nanoparticles in testicular cells. Toxicology 291:1-3, pages 65-72.
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