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Review Article

Molecular mechanisms of paraquat-induced acute lung injury: a current review

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Pages 130-134 | Received 30 Mar 2013, Accepted 04 Jul 2013, Published online: 07 Jan 2014

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Jiajun Xu, Jiantao Zhen, Jingfa Zhu & Qingming Lin. (2016) Tumor necrosis factor-α induced protein 6 attenuates acute lung injury following paraquat exposure. Toxicology Mechanisms and Methods 26:1, pages 32-35.
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Hongguang Gao, Dan Du & Yu Cao. (2014) Effects of alcohol before, during and after acute paraquat poisoning in rats. Toxin Reviews 33:4, pages 221-226.
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Zhiqiang Zhang, Qing Nian, Gang Chen, Shuqing Cui, Yuzhen Han & Jinying Zhang. (2020) Klotho Alleviates Lung Injury Caused by Paraquat via Suppressing ROS/P38 MAPK-Regulated Inflammatory Responses and Apoptosis. Oxidative Medicine and Cellular Longevity 2020, pages 1-13.
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Da-Zhuang Sun, Chun-Qing Song, Yong-Min Xu, Rui Wang, Wei Liu, Zhi Liu & Xue-Song Dong. (2018) Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells. Toxicology in Vitro 53, pages 148-159.
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Yifei Liu, Zhengyi Li, Xiaoxu Xue, Yong Wang, Yijie Zhang & Junpeng Wang. (2018) Apigenin reverses lung injury and immunotoxicity in paraquat-treated mice. International Immunopharmacology 65, pages 531-538.
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Hanting Fan, Huijie Huang, Li Hu, Wenjia Zhu, Yanfang Yu, Jiaqian Lou, Lingli Hu & Feng Chen. (2018) The activation of STIM1 mediates S-phase arrest and cell death in paraquat induced acute lung intoxication. Toxicology Letters 292, pages 123-135.
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Zun-Qi Liu, Hai-Shi Wang & Yan Gu. (2016) Hypokalemia is a biochemical signal of poor prognosis for acute paraquat poisoning within 4 hours. Internal and Emergency Medicine 12:6, pages 837-843.
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Linshen Xie, Dingzi Zhou, Jingyuan Xiong, Jia You, Ye Zeng & Lijun Peng. (2016) Paraquat induce pulmonary epithelial?mesenchymal transition through transforming growth factor-?1-dependent mechanism. Experimental and Toxicologic Pathology 68:1, pages 69-76.
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Qiong Shi, Xiufang Song, Juanli Fu, Chuanyang Su, Xiaomin Xia, Erqun Song & Yang Song. (2015) Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice. International Immunopharmacology 29:2, pages 722-729.
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Rong Yao, Yarong He, Zhi Zeng, Zongan Liang & Yu Cao. (2015) Protective effect of adiponectin on paraquat-induced pulmonary fibrosis in mice. Molecular & Cellular Toxicology 11:2, pages 247-255.
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Jing Tang, Zhenbao Liu, Yue Zhang, Ling Wang, Dai Li, Jinsong Ding & Xuehua Jiang. (2015) Fluorofenidone-loaded PLGA microspheres for targeted treatment of paraquat-induced acute lung injury in rats. RSC Advances 5:38, pages 30153-30159.
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